초록 ▼

A nutritional supplement, prepared food product, or direct food additive for ingestion by mammals, and methods for preparing such products, are provided. Products of the invention comprise an oxidation-resistant fat-based composition substantially free of exogenous solubilizing and dispersing agents

A nutritional supplement, prepared food product, or direct food additive for ingestion by mammals, and methods for preparing such products, are provided. Products of the invention comprise an oxidation-resistant fat-based composition substantially free of exogenous solubilizing and dispersing agents for phytosterols. The fat-based composition includes greater than 25% and less than 75% by weight of one or more triglyceride-based edible oil or fat, and greater than 25% and less than 75% by weight of one or more non-esterified phytosterols. The fat-based composition, when exposed to air, contains a reduced amount of oxidative by-products compared to a similar fat-based composition lacking non-esterified phytosterols. Also provided are methods for reducing plasma cholesterol in mammals, and methods for protecting plasma lipoproteins and cholesterol from oxidation by ingestion of products of the invention.

대표청구항 ▼

What is claimed is: 1. A product comprising: a fat-based composition substantially free of exogenous solubilizing and dispersing agents for phytosterols, wherein said fat-based composition comprises: greater than 25% and less than 75% by weight of one or more triglyceride-based edible oil or fat;

What is claimed is: 1. A product comprising: a fat-based composition substantially free of exogenous solubilizing and dispersing agents for phytosterols, wherein said fat-based composition comprises: greater than 25% and less than 75% by weight of one or more triglyceride-based edible oil or fat; and greater than 25% and less than 75% by weight of one or more non-esterified phytosterols that have been converted to triglyceride-recrystallized phytosterols; wherein said product is edible; wherein said product is useful as a component of a dietary supplement; and wherein said one or more triglyceride-based edible oil or fat comprises at least 10% by weight omega-3 fatty acids. 2. The product of claim 1, wherein said fat-based composition is exposed to air and contains a reduced amount of oxidative by-products compared to an otherwise similar fat-based composition lacking said non-esterified phytosterols. 3. The product of claim 1, wherein said one or more triglyceride-based edible oil or fat is selected from the group consisting of vegetable oils, vegetable fats, animal oils, animal fats, and mixtures thereof. 4. The product of claim 1, wherein said one or more triglyceride-based edible oil or fat is further selected from the group consisting of safflower oil, sunflower oil, corn oil, cottonseed oil, soybean oil, canola oil, peanut oil, coconut oil cocoa butter, palm oil, palm olein, palm super-olein, palm kernel oil, algae oil, flaxseed oil, and combinations thereof. 5. The product of claim 1, wherein said one or more triglyceride-based edible oil or fat is selected from the group consisting of butter, anhydrous milk fat, tallow, lard, mutton fat, poultry fat, fish oil, and combinations thereof. 6. The product of claim 5, wherein said one or more triglyceride-based edible oil or fat is cholesterol-free or cholesterol-reduced. 7. The product of claim 1 wherein said one or more triglyceride-based edible oil or fat is selected from the group consisting of natural vegetable and animal fats, structurally rearranged or otherwise modified vegetable and animal fats, and combinations thereof. 8. The product of claim 1 wherein one or more of said one or more non-esterified phytosterols is selected from the group consisting of vegetable oil-derived phytosterols, tall oil-derived phytosterols, and combinations thereof. 9. The product of claim 1 wherein one or more of said one or more non-esterified phytosterols is selected from the group consisting of beta-sitosterol, beta-sitostanol, campesterol, campestanol, stigmasterol, stigmastanol, brassicasterol, brassicastanol, clionasterol, clionastanol, and combinations thereof. 10. The product of claim 1, wherein said triglyceride-recrystallized phytosterols are formed by heating said fat-based composition either alone or combined in said product to a temperature and for a time sufficient to dissolve said one or more non-esterified phytosterols, and subsequently cooling said fat-based composition to allow said triglyceride-recrystallized phytosterols to be formed. 11. The product of claim 1, wherein said product comprises a member selected from the group consisting of margarines, spreads, butter, frying shortenings, baking shortenings, mayonnaises, salad dressings, dairy products, nut butters, seed butters, kernel butters, peanut butter, chocolate, fried snack foods, leavened bakery products comprising a flour, potato chips, French fries, corn chips, tortilla chips, popcorn, crackers, condiments, and sauces. 12. The product of claim 11, wherein said leavened bakery product is selected from the group consisting of cakes, muffins, donuts, pastries, breads and rolls. 13. The product of claim 11, wherein said condiment is selected from the group consisting of tomato catsup, mustard, barbecue sauce, steak sauce, Worchestershire sauce, cocktail sauce, tartar sauce, and pickle relish. 14. The product of claim 11, wherein said sauce is selected from the group consisting of tomato-based pasta sauce, pizza sauce, prepared chili, and dessert sauce. 15. The product of claim 1, wherein the oxidation rate of said fat-based composition is at least 20% lower than the oxidation rate for the same one or more triglyceride-based edible oil or fat lacking phytosterols. 16. The product of claim 1 wherein said omega-3 fatty acids are selected from the group consisting of DHA, EPA, alpha-linolenic acid, and combinations thereof. 17. The product of claim 1 wherein said one or more triglyceride-based edible oil or fat is selected from the group consisting of fish oil, cholesterol-reduced fish oil cholesterol-free fish oil, algae oil, flaxseed oil, and combinations thereof. 18. The product of claim 1 wherein said fat-based composition is packaged in edible gelatin capsules. 19. A method for reducing plasma cholesterol levels in mammals, comprising: regularly ingesting a product comprising: a fat-based composition substantially free of exogenous solubilizing and dispersing agents for phytosterols, wherein said fat-based composition comprises: greater than 25% and less than 75% by weight of one or more triglyceride-based edible oil or fat; and greater than 25% and less than 75% by weight of one or more non-esterified phytosterols that have been converted to triglyceride-recrystallized phytosterols; wherein said product is edible; wherein said product is useful as a component of a member of the group consisting of prepared foods, dietary supplements, and direct food additives; and wherein the plasma concentration of carotenoids comprising alpha-and beta-carotene is maintained essentially constant while said plasma cholesterol levels are reduced. 20. The method of claim 19 wherein between 0.4 g and 4.0 g of said non-esterified phytosterols are ingested daily by humans. 21. The method of claim 19 wherein said triglyceride-recrystallized phytosterols arc formed by heating said one or more triglyceride-based edible oil or fat and said one or more non-esterified phytosterols to a temperature of at least 60° C. for a period of time sufficient to dissolve said non-esterified phytosterols, and subsequently cooling said composition to room temperature to cause said triglyceride-recrystallized phytosterols to be formed. 22. A method for reducing plasma cholesterol levels in mammals, comprising: regularly ingesting a product comprising: a fat-based composition substantially free of exogenous solubilizing and dispersing agents for phytosterols, wherein said fat-based composition comprises: greater than 25% and less than 75% by weight of one or more triglyceride-based edible oil or fat; and greater than 25% and less than 75% by weight of one or more non-esterified phytosterols that have been converted to triglyceride-recrystallized phytosterols; wherein said product is edible; wherein said product is useful as a component of a member of the group consisting of prepared foods, dietary supplements, and direct food additives; wherein said one or more triglyceride-based edible oil or fat comprises at least 10% by weight omega-3 fatty acids comprising DHA or DHA in combination with EPA, and wherein the levels of plasma triglycerides and cholesterol are simultaneously reduced. 23. A method for protecting plasma lipoproteins and cholesterol from oxidation in mammals, comprising: regularly ingesting a product comprising: a fat-based composition substantially free of exogenous solubilizing and dispersing agents for phytosterols, wherein said fat-based composition comprises: greater than 25% and less than 75% by weight of one or more triglyceride-based edible oil or fat; and greater than 25% and less than 75% by weight of one or more non-esterified phytosterols that have been converted to triglyceride-recrystallized phytosterols; wherein said product is edible; and wherein said product is useful as a component of a member of the group consisting of prepared foods, dietary supplements, and direct food additives. 24. The method of claim 23 wherein between 0.4 g and 4.0 g of said non-esterified phytosterols are ingested daily by humans. 25. The method of claim 23 wherein said triglyceride-recrystallized phytosterols are formed by heating said one or more triglyceride-based edible oil or fat and said one or more non-esterified phytosterols to a temperature of at least 60° C. for a period of time sufficient to dissolve said non-esterified phytosterols, and subsequently cooling said composition to room temperature to cause said triglyceride-recrystallized phytosterols to be formed. 26. A product comprising: a fat-based composition substantially free of exogenous solubilizing and dispersing agents for phytosterols, wherein said fat-based composition comprises: greater than 25% and less than 75% by weight of one or more triglyceride-based edible oil or fat; and greater than 50% and less than 75% by weight of one or more non-esterified phytosterols that have been converted to triglyceride-recrystallized phytosterols. 27. The product of claim 26, wherein said fat-based composition comprises greater than 60% and less than 75% by weight of one or more non-esterified phytosterols that have been converted to triglyceride-recrystallized phytosterols. 28. The product of claim 26, wherein said product is edible; wherein said product is useful as a component of a member of the group consisting of prepared foods, dietary supplements, and direct food additives. 29. The product of claim 28, useful as a dietary supplement wherein said one or more triglyceride-based edible oil or fat comprises at least 10% by weight omega-3 fatty acids. 30. The product of claim 29, wherein said omega-3 fatty acids are selected from the group consisting of DHA, EPA, alpha-linolenic acid, and combinations thereof. 31. The product of claim 29, wherein said one or more triglyceride-based edible oil or fat is selected from the group consisting of fish oil, cholesterol-reduced fish oil, cholesterol-free fish oil, algae oil, flaxseed oil, and combinations thereof. 32. The product of claim 29, wherein said fat-based composition is packaged in edible gelatin capsules. 33. The product of claim 26, wherein said fat-based composition is exposed to air and contains a reduced amount of oxidative by-products compared to an otherwise similar fat-based composition lacking said non-esterified phytosterols. 34. The product of claim 26, wherein said one or more triglyceride-based edible oil or fat is selected from the group consisting of vegetable oils, vegetable fats, animal oils, animal fats, and mixtures thereof. 35. The product of claim 26, wherein said one or more triglyceride-based edible oil or fat is further selected from the group consisting of safflower oil, sunflower oil, corn oil, cottonseed oil, soybean oil, canola oil, peanut oil, coconut oil, cocoa butter, palm oil, palm olein, palm super-olein, palm kernel oil, algae oil, flaxseed oil, and combinations thereof. 36. The product of claim 26, wherein said one or more triglyceride-based edible oil or fat is selected from the group consisting of butter, anhydrous milk fat, tallow, lard, mutton fat, poultry fat, fish oil, and combinations thereof. 37. The product of claim 36, wherein said one or more triglyceride-based edible oil or fat is cholesterol-free or cholesterol-reduced. 38. The product of claim 26, wherein said one or more triglyceride-based edible oil or fat is selected from the group consisting of natural vegetable and animal fats, structurally rearranged or otherwise modified vegetable and animal fats, and combinations thereof. 39. The product of claim 26, wherein one or more of said one or more non-esterified phytosterols is selected from the group consisting of vegetable oil-derived phytosterols, tall oil-derived phytosterols, and combinations thereof. 40. The product of claim 26, wherein one or more of said one or more non-esterified phytosterols is selected from the group consisting of beta-sitosterol, beta-sitostanol, campesterol, campestanol, stigmasterol, stigmastanol, brassicasterol, brassicastanol, clionasterol, chonastanol, and combinations thereof. 41. The product of claim 26, wherein said triglyceride-recrystallized phytosterols are formed by heating said fat-based composition either alone or combined in said product to a temperature and for a time sufficient to dissolve said one or more non-esterified phytosterols, and subsequently cooling said fat-based composition to allow said triglyceride-recrystallized phytosterols to be formed. 42. The product of claim 26, wherein said product comprises a member selected from the group consisting of margarines, spreads, butter, flying shortenings, baking shortenings, mayonnaises, salad dressings, dairy products, nut butters, seed butters, kernel butters, peanut butter, chocolate, fried snack foods, leavened bakery products comprising a flour, potato chips, French fries, corn chips, tortilla chips, popcorn, crackers, condiments, and sauces. 43. The product of claim 42, wherein said leavened bakery product is selected from the group consisting of cakes, muffins, donuts, pastries, breads and rolls. 44. The product of claim 42, wherein said condiment is selected from the group consisting of tomato catsup, mustard, barbecue sauce, steak sauce, Worchestershire sauce, cocktail sauce, tartar sauce, and pickle relish. 45. The product of claim 42, wherein said sauce is selected from the group consisting of tomato-based pasta sauce, pizza sauce, prepared chili, and dessert sauce. 46. The product of claim 26, wherein the oxidation rate of said fat-based composition is at least 20% lower than the oxidation rate for the same one or more triglyceride-based edible oil or fat lacking phytosterols.