Method of treating biological and chemical agents with gas phase, electronically excited states of oxygen
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A62B-007/08
A62B-007/00
A61L-009/00
B01J-019/08
A61L-002/00
A62C-031/00
B05B-007/04
B05B-007/08
B05B-007/02
C02F-001/76
C02F-001/72
C02F-001/68
H01S-003/22
H01S-003/14
A24B-001/02
A24B-001/00
출원번호
UP-0795715
(2004-03-08)
등록번호
US-7595020
(2009-10-12)
발명자
/ 주소
Emanuel, George
출원인 / 주소
KSY Corporation
대리인 / 주소
Storm LLP
인용정보
피인용 횟수 :
0인용 특허 :
10
초록▼
An improved singlet oxygen generator (SOG) and method of using gas phase electronically excited states of oxygen for bio-medical and chemical treatment applications are disclosed. According to the invention, both gas phase O2(1Σ) and O2(1Δ) are used for medical treatment, sterilization, an
An improved singlet oxygen generator (SOG) and method of using gas phase electronically excited states of oxygen for bio-medical and chemical treatment applications are disclosed. According to the invention, both gas phase O2(1Σ) and O2(1Δ) are used for medical treatment, sterilization, and deactivation of biological and chemical agents, including diseased tissue and biological and chemical weapons. The improved SOG is compact and scalable, portable, capable of operating in a zero-gravity or low gravity environment, may use gaseous diluent or buffer gas, and is capable of operating at pressures as high as one atmosphere. The SOG is capable of operating within a short distance of the target site for the electronically excited states of oxygen, which are delivered to the target site via a conduit. The SOG and delivery system provide higher yields of electronically excited oxygen with longer lifetimes suitable for bio-medical applications.
대표청구항▼
The invention claimed is: 1. A method of treating a chemical species or pathogen, the method comprising: feeding a flow of basic hydrogen peroxide (BHP) to a Singlet Delta Oxygen generator (SOG) having an inner wall that includes a curved inner wall portion so that the BHP flows as a liquid layer a
The invention claimed is: 1. A method of treating a chemical species or pathogen, the method comprising: feeding a flow of basic hydrogen peroxide (BHP) to a Singlet Delta Oxygen generator (SOG) having an inner wall that includes a curved inner wall portion so that the BHP flows as a liquid layer along a surface of the inner wall of the SOG; contacting the liquid layer with chlorine to produce Singlet Delta Oxygen; separating Singlet Delta Oxygen from the liquid layer by utilizing centrifugal forces generated by flowing the liquid layer along a surface of the curved inner wall portion of the SOG; exhausting the Singlet Delta Oxygen through an outlet at a total pressure that is greater than ambient pressure and exhausting the liquid layer via a different outlet; directing the exhausted flow of Singlet Delta Oxygen through a duct; and contacting the chemical species or pathogen with Singlet Delta Oxygen. 2. The method of claim 1, wherein the step of directing further comprises introducing a diluent to the flow of Singlet Delta Oxygen at a partial pressure sufficient to provide a total pressure that is greater than ambient pressure. 3. The method of claim 2 wherein the diluent is argon. 4. The method of claim 1 wherein the pathogen is a tumor. 5. The method of claim 1 wherein the pathogen is a biofilm. 6. The method of claim 1 wherein the chemical species or pathogen is a chemical or biological weapon. 7. The method of claim 6 wherein the chemical species or pathogen is treated without first identifying the species or pathogen. 8. The method of claim 1 wherein the SOG is external to the chemical species or pathogen being treated. 9. The method of claim 1, wherein the method further comprises transporting the SOG to the chemical species or pathogen. 10. The method of claim 1, wherein the step of directing further comprises directing the flow of Singlet Delta Oxygen through a hose. 11. The method of claim 1, wherein the step of contacting to produce Singlet Delta Oxygen comprises providing stoichiometrically sufficient moles of chlorine to react with about 80% to about 95% of hydroxide in the fluid fed to the SOG. 12. The method of claim 1, wherein the step of feeding so that the BHP moves as a liquid layer comprises feeding so that the liquid layer has a thickness about 15 mm or less. 13. The method of claim 1, wherein the contacting with chlorine comprises introducing, and rapidly mixing, chlorine vapor as bubbles into the liquid layer and reacting BHP with the chlorine vapor. 14. The method of claim 1, wherein the step of feeding comprises feeding at a pressure greater than about 400 Torr. 15. The method of claim 1, wherein the step of feeding comprises feeding at a pressure greater than about 600 Torr. 16. The method of claim 1, further comprising, prior to the step of feeding a flow of BHP, cooling the BHP to a temperature where the water vapor pressure thereof is below 4.6 Torr. 17. The method of claim 1, wherein the step of exhausting comprises exhausting a fluid comprising Singlet Delta Oxygen that is substantially free of chlorine. 18. The method of claim 1, wherein a time period from the step of feeding the fluid to the step of exhausting the liquid layer is less than about 20 milliseconds. 19. A method of treating a chemical species or pathogen, the method comprising: feeding a fluid comprising basic hydrogen peroxide (BHP) and hydroxides at a pressure greater than about 400 Torr to a Singlet Delta Oxygen generator (SOG) having an inner wall, the inner wall including a curved inner wall portion, so that the BHP moves as a liquid layer along the inner wall of the SOG; flowing the fluid as a liquid layer in contact with and along the inner wall of the SOG; injecting chlorine vapor into the SOG while flowing the fluid as a liquid layer; contacting the fluid flowing as a liquid layer with the injected chlorine vapor and thereby mixing the chlorine vapor in the form of chlorine bubbles in the liquid layer, to react to produce Singlet Delta Oxygen; utilizing centrifugal forces generated when flowing the liquid layer along the curved inner wall portion of the SOG to separate Singlet Delta Oxygen from the liquid layer; exhausting a fluid product comprising Singlet Delta Oxygen, substantially free of chlorine, through an outlet of the SOG proximate the curved inner wall portion of the SOG; and contacting the chemical species or pathogen with the fluid product. 20. The method of claim 19, wherein the step of injecting chlorine comprises injecting chlorine uniformly along a length of the SOG. 21. The method of claim 19, wherein the step of injecting chlorine comprises injecting sufficient moles of chlorine to react with about 80% to about 95% of the molar flow rate of hydroxide in the fluid fed to the SOG. 22. The method of claim 19, wherein the step of feeding comprises feeding at a pressure greater than about 600 Torr. 23. The method of claim 19, further comprising, prior to the step of feeding a flow of BHP, cooling the BHP to a temperature where the water vapor pressure thereof is below 4.6 Torr.
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