Implant for in-vivo parameter monitoring, processing and transmitting
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A61B-005/00
A61B-005/103
A61B-005/117
출원번호
UP-0374928
(2003-02-24)
등록번호
US-7621878
(2009-12-02)
발명자
/ 주소
Ericson, Milton N.
McKnight, Timothy E.
Smith, Stephen F.
Hylton, James O.
출원인 / 주소
UT Battelle, LLC
대리인 / 주소
Brinks Hofer Gilson & Lione
인용정보
피인용 횟수 :
22인용 특허 :
43
초록▼
The present invention relates to a completely implantable intracranial pressure monitor, which can couple to existing fluid shunting systems as well as other internal monitoring probes. The implant sensor produces an analog data signal which is then converted electronically to a digital pulse by gen
The present invention relates to a completely implantable intracranial pressure monitor, which can couple to existing fluid shunting systems as well as other internal monitoring probes. The implant sensor produces an analog data signal which is then converted electronically to a digital pulse by generation of a spreading code signal and then transmitted to a location outside the patient by a radio-frequency transmitter to an external receiver. The implanted device can receive power from an internal source as well as an inductive external source. Remote control of the implant is also provided by a control receiver which passes commands from an external source to the implant system logic. Alarm parameters can be programmed into the device which are capable of producing an audible or visual alarm signal. The utility of the monitor can be greatly expanded by using multiple pressure sensors simultaneously or by combining sensors of various physiological types.
대표청구항▼
What is claimed is: 1. An implant for monitoring intracranial cerebral spinal fluid pressure of a subject, comprising: a pressure transducer having a deflectable membrane separating a reference chamber and a local intracranial pressure chamber, the local intracranial pressure chamber in fluid commu
What is claimed is: 1. An implant for monitoring intracranial cerebral spinal fluid pressure of a subject, comprising: a pressure transducer having a deflectable membrane separating a reference chamber and a local intracranial pressure chamber, the local intracranial pressure chamber in fluid communication with a shunt to receive cerebral spinal fluid, wherein a deflection of the deflectable membrane indicates a pressure differential between the reference chamber and the local intracranial pressure chamber, the deflection being measured by a strain measurement means, the pressure transducer configured to generate a signal representing the measured deflection; a system controller coupled to the pressure transducer, the system controller including a processor configured to receive and process the generated signal and a transmitter configured to wirelessly transmit said processed signal; a power source coupled to the system controller and configured to power said system controller, wherein the power source includes an energy storage device and an inductive coil; and a single housing adapted to fully enclose the pressure transducer, the system controller, the energy storage device and the inductive coil and sized to be fully implanted at a single location surrounding the shunt within a head of said subject, wherein the inductive coil is configured to receive inductive power from an inductive power source positioned outside the single housing, the inductive power source operable to induce current in said inductive coil to recharge the energy storage device and power the system controller. 2. The implant of claim 1, further comprising a power managing circuit included in the single housing and coupled to the power source and configured to regulate operation of the power source. 3. The implant of claim 2, wherein the power managing circuit is configured to monitor power consumption levels of the implant. 4. The implant of claim 2, wherein said processor performs the following functions to regulate operation of the power source, including: enabling the energy storage device to power the system controller in the absence of inductive power; and selectively enabling inductive power induced in the inductive coil to recharge the energy storage device and power the system controller during wireless transmittal of data from the system controller to a monitoring device external to the single housing. 5. The implant of claim 2, wherein the power managing circuit is configured to monitor at least one of a charge of the energy storage device and a voltage of the power source. 6. The implant of claim 2, wherein the inductive power source includes an energizing coil and a driving circuit having an impedance. 7. The implant of claim 6, wherein the power managing circuit includes a matching circuit having an impedance, wherein the impedance of the matching circuit is configured to optimally match the impedance of the driving circuit of the inductive power source. 8. The implant of claim 2, wherein the power managing circuit is coupled to the system controller and configured to monitor a charge of the energy storage device and a voltage of the power source. 9. The implant of claim 8, wherein the inductive power source is configured to automatically trigger the system controller to wirelessly transmit data representing the charge of the energy storage device and the voltage of the power source via said transmitter. 10. The implant of claim 8, wherein the inductive power source is configured to automatically trigger the system controller to wirelessly transmit data representing the pressure of the cerebral spinal fluid via said transmitter. 11. The implant of claim 1, wherein the inductive coil comprises a planarized coil disposed along a perimeter of the implant to minimize the overall size of the implant. 12. The implant of claim 1, wherein the inductive power of the inductive coil of the power source has a resonant frequency in a range of 100 kHz to 1 MHz. 13. The implant of claim 1, wherein the energy storage device comprises a battery and a capacitive device coupled to the battery. 14. The implant of claim 1, wherein the power source includes a capacitive device. 15. The implant of claim 1, further comprising an antenna included in the single housing and coupled to the system controller, the antenna configured to transmit and receive data. 16. The implant of claim 1, wherein the transmitter is configured to wirelessly transmit a command signal to a shunt valve external to the single housing and coupled to the shunt, the shunt valve operable to shunt cerebral spinal fluid away from a ventricle of the head of said subject. 17. The implant of claim 16, wherein only the energy storage device is operable to power the system controller to monitor the cerebral spinal fluid pressure and transmit the command signal to the shunt valve to compensate for fluctuations in pressure in the absence of inductive power. 18. The implant of claim 1, wherein the inductive power induced in the inductive coil is selectively enabled to recharge the energy storage device and power the system controller during wireless transmittal of data from the system controller to a monitoring device external to the single housing. 19. The implant of claim 1, wherein the pressure transducer includes a plurality of pressure transducers each coupled to the shunt to receive cerebral spinal fluid, and wherein said processor is configured to evaluate the performance of the pressure transducers and detect degradation of the pressure transducers. 20. The implant of claim 19, wherein said processor performs the following functions to evaluate the performance of the pressure transducers and detect degradation of the pressure transducers, including: performing standard-deviation calculations of the deflection of the deflectable membrane of each of the plurality of pressure transducers; determining an average of the deflection of the deflectable membrane of each of the plurality of pressure transducers; determining the differential over time of the deflection of the deflectable membrane of each of the plurality of pressure transducers; and determining the minimum and maximum of the deflection of the deflectable membrane of each of the plurality of pressure transducers. 21. An implant for monitoring intracranial cerebral spinal fluid pressure of a subject, comprising: a pressure transducer coupled to a shunt and configured to generate a signal representing said intracranial cerebral spinal fluid pressure; a system controller coupled to the pressure transducer, the system controller including a processor configured to receive and process the generated signal and a hybrid spread-spectrum transmitter configured to wirelessly transmit said processed signal, the hybrid spread-spectrum transmitter including a spread-spectrum modulation configured to generate a spreading-code signal and to reduce substantially all multi-path reflection errors, wherein the spread-spectrum modulation comprises direct-sequence modulation, frequency-hopping modulation, and time-hopping modulation; a power source coupled to the system controller and configured to power said system controller, wherein the power source includes an energy storage device and an inductive coil; and a single housing adapted to fully enclose the pressure transducer, the system controller, the energy storage device and the inductive coil and sized to be fully implanted at a single location surrounding the shunt within a head of said subject, wherein the inductive coil is configured to receive inductive power from an inductive power source positioned outside the single housing, the inductive power source operable to induce current in said inductive coil to recharge the energy storage device and power the system controller. 22. The implant of claim 21, wherein said hybrid spread-spectrum transmitter is a radio frequency transmitter configured to operate in a frequency including at least one of 902-928 MHz, 2450-2483.5 MHz, 5150-5250 MHz, and 57250-5825 MHz. 23. The implant of claim 21, wherein said hybrid spread-spectrum transmitter is a radio frequency transmitter configured to operate in a frequency greater than 1 GHz. 24. The implant of claim 21, wherein said hybrid spread-spectrum transmitter is an ultrasonic transmitter. 25. The implant of claim 21, wherein said transmitter is configured to transmit a processed signal through multiple-access spread-spectrum transmission including code division, frequency-division and time division multiplexing. 26. The implant of claim 21, further includes an monitoring device external to the single housing and having a receiver configured to receive said processed signal from the hybrid spread-spectrum transmitter. 27. The implant of claim 26, wherein said receiver includes an audible or visual alarm configured to activate upon receipt of said processed signal outside a predetermined tolerance range. 28. The implant of claim 26, wherein the transmitter is configured to wirelessly transmit a command signal to a shunt valve external to the single housing and coupled to the shunt, the shunt valve operable to shunt cerebral spinal fluid away from a ventricle of the head of said subject. 29. The implant of claim 28, wherein only the energy storage device is operable to power the system controller to monitor the cerebral spinal fluid pressure and transmit the command signal to the shunt valve to compensate for fluctuations in pressure in the absence of inductive power. 30. The implant of claim 29, the inductive power induced in the inductive coil is selectively enabled to recharge the energy storage device and power the system controller during wireless transmittal of data from the system controller to a monitoring device external to the single housing. 31. The implant of claim 21, further comprising a plurality of sensors included in the single housing and coupled to the system controller, wherein the sensors are configured to sense physiological parameters.
연구과제 타임라인
LOADING...
LOADING...
LOADING...
LOADING...
LOADING...
이 특허에 인용된 특허 (43)
Goedeke Steven D. (Forest Lake MN) Haubrich Gregory J. (Champlin MN) Keimel John G. (New Brighton MN) Thompson David L. (Fridley MN), Adaptive, performance-optimizing communication system for communicating with an implanted medical device.
Goedeke Steven D. ; Haubrich Gregory J. ; Keimel John G. ; Thompson David L., Adaptive, performance-optimizing communication system for communicating with an implanted medical device.
Russek Linda G. (The Russek Foundation 1200 N. Federal Highway ; Suite 209 Boca Raton FL 33432), Alarm for patient monitor and life support equipment system.
Cox Timothy J. (Lake Jackson TX) Armstrong Randolph K. (Missouri City TX), Apparatus for high speed data communication between an external medical device and an implantable medical device.
Brockway Brian P. (Minneapolis MN) Mills Perry A. (Roseville MN) Miller Jonathan T. (St. Paul MN), Device for chronic measurement of internal body pressure.
Markowitz Raymond S. (Elkins Park PA) Roy Robert E. (Herndon VA) Sun Xiaoguang G. (King of Prussia PA), Medical telemetry system using an implanted passive transponder.
Merritt Donald R. (Brooklyn Center MN) Howard William G. (St. Paul MN) Skarstad Paul M. (Plymouth MN) Weiss Douglas J. (Plymouth MN) Wyborny Paul B. (Coon Rapids MN) Roline Glenn M. (Anoka MN) Nichol, Method and apparatus for determination of end-of-service for implantable devices.
Lai Joseph ; Buyan Lawrence A. ; DuBore Renee S. ; Pate Brian Lewis ; Reuss James L., Method and system for remotely monitoring multiple medical parameters.
Duffin Edwin G. ; Thompson David L. ; Goedeke Steven D. ; Haubrich Gregory J., World wide patient location and data telemetry system for implantable medical devices.
Bertrand, William Jeffrey; Vaccaro, Robert K.; Man Alan Leung, Chun; Ayoub, Michael; Jaquier, Pierre; Mayor, Laetitia; Junker, Thomas; Schmit, Guillaume, Adjustment for hydrocephalus shunt valve.
Cros, Florent; O'Brien, David; Fonseca, Michael; Abercrombie, Matthew; Park, Jin Woo; Singh, Angad, Method of manufacturing implantable wireless sensor for in vivo pressure measurement.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.