An ultrafiltration device adapted to be worn on a portion of the body of a patient includes a blood inlet tube leading from a first blood vessel, a blood pump, an anticoagulant reservoir for infusing anticoagulants into the blood, a blood filter including a substrate through which the blood is circu
An ultrafiltration device adapted to be worn on a portion of the body of a patient includes a blood inlet tube leading from a first blood vessel, a blood pump, an anticoagulant reservoir for infusing anticoagulants into the blood, a blood filter including a substrate through which the blood is circulated and filtered, a fluid bag for storing the excess fluid and a blood outlet tube leading to a second blood vessel.
대표청구항▼
What is claimed is: 1. A portable, wearable ultrafiltration device comprising: a blood inlet for receiving blood flow from a patient; a pulsatile blood pump connected to the blood inlet, the pulsatile pump configured to pump blood from the patient in a pulsatile manner through the ultrafiltration d
What is claimed is: 1. A portable, wearable ultrafiltration device comprising: a blood inlet for receiving blood flow from a patient; a pulsatile blood pump connected to the blood inlet, the pulsatile pump configured to pump blood from the patient in a pulsatile manner through the ultrafiltration device at a flow rate between 10 and 70 ml/min.; a blood filter for filtering excess body fluid from said blood, the blood filter including a filter inlet connected to the pulsatile blood pump and a fixed semiporous filter material having a first surface in contact with the patient's blood and a second surface on which fluid from the patient's blood is received, the pulsatile pump pumping the patient's blood to and through the filter with sufficient pressure to force fluid from the blood through the semiporous filter material, the blood filter having a blood side and a fluid side configured so that the only fluid on the fluid side of the blood filter is fluid separated from the blood passing through the blood side of the blood filter, the rate of fluid separation from the blood is configured to be adjusted by a combination of the flow rate being between 10 and 70 ml/min and by variably controlling a continuous fluid flow from the blood filter; a blood outlet connected to the blood filter, the blood outlet receiving blood from the blood filter and conducting the blood back to the patient; and a fluid bladder including a bladder inlet connected to the fluid side of the blood filter, the fluid bladder receiving and collecting fluid from the fluid side of the blood filter, the wearable ultrafiltration device constructed and configured to operate while in various three-dimensional orientations on the body of the patient. 2. The portable, wearable ultrafiltration device of claim 1 wherein the device weighs less than five (5) pounds. 3. The portable, wearable ultrafiltration device of claim 1 wherein the pulsatile pump pumps blood through the filter in a pulsed manner at a flow rate of between 15 and 200 ml/min. 4. The portable, wearable ultrafiltration device of claim 1, further comprising: an anticoagulant reservoir; and a first micropump for pumping anticoagulant from said anticoagulant reservoir into said blood at a location between said blood inlet and said blood filter. 5. The portable, wearable ultrafiltration device of claim 1, further comprising a microcontroller programmed to control said pulsatile pump flow rate and a variable continuous fluid flow from the blood filter. 6. The portable, wearable ultrafiltration device of claim 5, further comprising a moisture sensor inside a covering about said ultrafiltration device, said moisture sensor providing a moisture signal to said microcontroller when moisture is sensed inside said covering. 7. The portable, wearable ultrafiltration device of claim 6, wherein said microcontroller provides a signal that turns said pulsatile pump off after receiving said moisture signal when moisture is sensed inside said covering. 8. The portable, wearable ultrafiltration device of claim 5, further comprising a bladder sensor for sensing a fullness of said fluid bladder, said bladder sensor configured to provide a full signal to said microcontroller when said bladder sensor senses that said fluid bladder is full. 9. The portable, wearable ultrafiltration device of claim 5, further comprising a battery device configured to power the wearable ultrafiltration device continuously for at least six to twenty-four hours. 10. The portable, wearable ultrafiltration device of claim 1, wherein said fluid bladder contains an absorbent material that reduces the movement of the fluid within said fluid bladder. 11. A portable, wearable ultrafiltration device comprising: a blood inlet for receiving blood flow from a patient; a pulsatile pump connected to the blood inlet for pumping blood from the blood inlet to and through the ultrafiltration device, the pulsatile pump establishing an adjustable pulsed blood flow rate of between 10 and 200 ml/min; a blood filter for filtering an ultrafiltrate fluid from said blood, the blood filter including a filter inlet connected to the pulsatile blood pump and a fixed semiporous filter material having a first surface in contact with the patient's blood and a second surface on which ultrafiltrate fluid from the patient's blood is received, the pulsatile pump configured to pump the patient's blood through the filter with sufficient pressure to force excess body fluid from the blood through the semiporous filter material, the blood filter having a blood side and a fluid side configured such that the only fluid on the fluid side of the blood filter is ultrafiltrate fluid separated from the blood passing through the blood side of the blood filter, the rate of ultrafiltrate removal being both continuous and adjustable by a combination of varying the blood flow rate between 10 and 200 ml/min and by controlling a continuous and variable ultrafiltrate flow from said blood filter, a blood outlet for returning said blood to said patient; and a fluid reservoir configured to receive said ultrafiltrate fluid from said blood filter and for temporarily storing said ultrafiltrate fluid; said ultrafiltration device configured to operate while in various three-dimensional orientations. 12. The portable, wearable ultrafiltration device of claim 11 further comprising a pump having an inlet connected to the fluid side of the blood filter and an outlet connected to the fluid reservoir, the pump pumping ultrafiltrate fluid from the blood filter to the fluid reservoir. 13. The portable, wearable ultrafiltration device of claim 11 further comprising an anticoagulant reservoir; and a micropump, the micropump pumping anticoagulant from said anticoagulant reservoir into the blood before the blood enters the blood filter. 14. The portable, wearable ultrafiltration device of claim 13 wherein the micropump pumps anticoagulant from the anticoagulant reservoir into the blood at a location between said blood pump and the blood filter. 15. The portable, wearable ultrafiltration device of claim 11 wherein the blood filter comprises a plurality of miniaturized blood filters connected in series. 16. The portable, wearable ultrafiltration device of claim 11 wherein the blood filter comprises a plurality of miniaturized blood filters connected in parallel. 17. The portable, wearable ultrafiltration device of claim 11 wherein the pulsatile pump further comprises a double channel pulsatile pump. 18. A portable, wearable ultrafiltration device comprising: a blood inlet for receiving blood flow from a patient; a battery device powered pulsatile blood pump connected to the blood inlet such that blood from the patient is pumped by the pulsatile pump through said ultrafiltration device; a blood filter for filtering overload body fluid from said blood, the blood filter including a blood side and a fluid side, the blood side having a blood filter inlet connected to the pulsatile blood pump and a blood filter outlet, the fluid side having a fluid outlet, the blood filter further comprising a fixed semiporous filter material having a first surface on the blood side of the blood filter in contact with the patient's blood and a second surface on the fluid side on which overload body fluid from the patient's blood is received, the pulsatile pump configured to pump the patient's blood through the filter with sufficient pressure to force overload body fluid from the blood through the semiporous filter material, the fluid side configured with no fluid inlet such that the only fluid on the fluid side of the blood filter is the overload body fluid separated from the blood that passes from the blood side of the blood filter to the fluid side of the filter through the semiporous filter material; the blood filter outlet receiving blood from the blood filter and conducting the blood back to the patient; and a fluid reservoir including a reservoir inlet connected to the blood filter and configured to receive the overload body fluid separated from the patient's blood, said overload body fluid being removed from the patient's blood at a continuous and an adjustable rate that can be varied by a combination of varying a pumping rate of the battery powered pulsatile pump and variably occluding a continuous overload body fluid flow from being received by the fluid reservoir; the wearable ultrafiltration device being configured to operate while in various three-dimensional orientations while being completely worn on the body of the patient. 19. The portable, wearable ultrafiltration device of claim 18 wherein the semiporous filter material comprises a plurality of hollow fibers having fixed ends.
연구과제 타임라인
LOADING...
LOADING...
LOADING...
LOADING...
LOADING...
이 특허에 인용된 특허 (34)
Gorsuch, Reynolds G.; Venkat, Kris, Apparatus and method for selective reduction of segmental intracellular and extracellular edema.
Yao Shang J. (5 Bayard Road - Apt. 920 Pittsburgh PA 15213) Wolfson Sidney K. (205 Buckingham Road Pittsburgh PA 15215), Blood and tissue detoxification apparatus.
Greenwood Roger N. (London GBX) Aldridge Colin (London GBX) Tattershall James E. (London GBX) Barrett Rodney V. (Bristol GBX), Blood purification apparatus.
Loughnane Michael H. (Lafayette Hill PA) Wiesmann William P. (Bethesda MD) Pearce Frederick J. (Olney MD) Kearney George P. (Durham NC), High effieciency balanced oscillating shuttle pump.
Levin, Howard R.; Gelfand, Mark; Bernard, Steve, Method and apparatus for ultrafiltration utilizing a long peripheral access venous cannula for blood withdrawal.
Sherman John D. ; Bem David S. ; Lewis Gregory J., Process for removing toxins from bodily fluids using zirconium or titanium microporous compositions.
Blott, Patrick Lewis; Greener, Bryan; Hartwell, Edward Yerbury; Walker, Tina Michelle; Nicolini, Derek; Lee-Webb, Julian, Apparatus for aspirating, irrigating and cleansing wounds.
Robinson, Thomas Patrick; Clemens, Charles E.; Mishelevich, David Jacob; Braig, James Roswell; Fulkerson, Barry Neil; Ghidoli, Daniele; Joseph, Russell Thomas, Disposable apparatus and kit for conducting dialysis.
Robinson, Thomas Patrick; Clemens, Charles E.; Mishelevich, David Jacob; Braig, James Roswell; Fulkerson, Barry Neil; Ghidoli, Daniele; Joseph, Russell Thomas, Disposable apparatus and kit for conducting dialysis.
Robinson, Thomas Patrick; Clemens, Charles E.; Mishelevich, David Jacob; Braig, James Roswell; Fulkerson, Barry Neil; Ghidoli, Daniele; Joseph, Russell Thomas, Disposable apparatus and kit for conducting dialysis.
DiPerna, Paul M.; Brown, David; Rosinko, Mike; Kincade, Dan; Michaud, Michael; Nadworny, John; Kruse, Geoffrey A.; Ulrich, Thomas R., Infusion pump system with disposable cartridge having pressure venting and pressure feedback.
DiPerna, Paul M.; Brown, David; Rosinko, Mike; Kincade, Dan; Michaud, Michael; Nadworny, John; Kruse, Geoffrey A.; Ulrich, Thomas R., Infusion pump system with disposable cartridge having pressure venting and pressure feedback.
Verhoef, Erik T.; DiPerna, Paul M.; Rosinko, Mike; Williamson, Mark; Kruse, Geoffrey A.; Ulrich, Thomas R.; Lamb, Phil; Saint, Sean; Michaud, Michael; Trevaskis, William, Infusion pump system with disposable cartridge having pressure venting and pressure feedback.
Fulkerson, Barry Neil; Fazio, Joe; Huang, Alec; Kelly, Brian Thomas; Nolan, Tam; Smith, Mark, Load suspension and weighing system for a dialysis machine reservoir.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.