IPC분류정보
국가/구분 |
United States(US) Patent
등록
|
국제특허분류(IPC7판) |
|
출원번호 |
UP-0355868
(2006-02-15)
|
등록번호 |
US-7674485
(2010-04-21)
|
발명자
/ 주소 |
- Bhaskaran, Sunil
- Mohan, Vishwaraman
|
출원인 / 주소 |
|
대리인 / 주소 |
|
인용정보 |
피인용 횟수 :
37 인용 특허 :
6 |
초록
▼
A composition for the treatment of diabetes in a subject in need thereof, said composition—comprising Trigonelline of concentration ranging between 20 to 30%, amino acids of concentration ranging between 20 to 60%, and soluble fiber of concentration ranging between 10 to 60%, optionally along
A composition for the treatment of diabetes in a subject in need thereof, said composition—comprising Trigonelline of concentration ranging between 20 to 30%, amino acids of concentration ranging between 20 to 60%, and soluble fiber of concentration ranging between 10 to 60%, optionally along with pharmaceutically acceptable additives, a process thereof and also, a method of treating diabetes.
대표청구항
▼
The invention claimed is: 1. A process for preparing a composition, the composition comprising: trigonelline of concentration ranging between 20 to 30% weight/weight (w/w), amino acids of concentration ranging between 20 to 60% w/w, and soluble fiber of concentration ranging between 10 to 60% w/w,
The invention claimed is: 1. A process for preparing a composition, the composition comprising: trigonelline of concentration ranging between 20 to 30% weight/weight (w/w), amino acids of concentration ranging between 20 to 60% w/w, and soluble fiber of concentration ranging between 10 to 60% w/w, optionally along with pharmaceutically acceptable additives, the process consisting steps of: a. flaking fenugreek (Trigonella foenum-graecum) seeds to obtain flaked seeds, b. extracting the flaked seeds with hydro-alcohol to obtain an extract, c. concentrating the extract under vacuum to remove alcohol to obtain a concentrate, d. extracting the concentrate with n-hexane to remove fats and lipids to obtain a defatted concentrate, e. diluting the defatted concentrate to obtain a diluted extract, f. filtering of the diluted extract to remove insolubles to obtain a resultant, g. subjecting the resultant to column chromatography wherein amino-acids, and trigonelline are eluted, and h. adding fiber of fenugreek into the amino acids and trigonelline to obtain the composition. 2. A process as claimed in claim 1, wherein the flaked seeds are extracted at a temperature ranging between 20 to 70° C. 3. A process as claimed in claim 1, wherein the flaked seeds are of size of about 15 millimeter(mm). 4. A process as claimed in claim 1, wherein the hydro-alcohol is isopropyl alcohol and water in equal ratio. 5. A process as claimed in claim 1, wherein the flaked seeds are extracted for a time duration ranging between 3 to 24 hours. 6. A process as claimed in claim 1, wherein the amino acids are selected from the group consisting of 1-arginine, leucine, isoleucine, and 4-hydroxyisoleucine. 7. A process as claimed in claim 1, wherein the column chromatography is ion exchange chromatography. 8. A process as claimed in claim 1, wherein the fiber is galactomannan. 9. A process as claimed in claim 2, wherein the flaked seeds are extracted at a temperature of 35° C. 10. A process as claimed in claim 5, wherein the flaked seeds are extracted for a time duration of 12 hours.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.