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다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
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Kafe 바로가기국가/구분 | United States(US) Patent 등록 |
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국제특허분류(IPC7판) |
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출원번호 | UP-0363508 (2002-06-12) |
등록번호 | US-7682318 (2010-04-21) |
국제출원번호 | PCT/US2002/019054 (2002-06-12) |
§371/§102 date | 20030903 (20030903) |
국제공개번호 | WO02/100252 (2002-12-19) |
발명자 / 주소 |
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출원인 / 주소 |
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대리인 / 주소 |
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인용정보 | 피인용 횟수 : 121 인용 특허 : 1037 |
Blood samples can be collected without substantial contamination from ambient air, such that the blood sample may be analyzed accurately for gaseous components such as oxygen and carbon dioxide. An embodiment of the device has integrated actuation, lancing, and sample acquisition components, which i
Blood samples can be collected without substantial contamination from ambient air, such that the blood sample may be analyzed accurately for gaseous components such as oxygen and carbon dioxide. An embodiment of the device has integrated actuation, lancing, and sample acquisition components, which in some embodiments are miniaturized and/or disposable.
The invention claimed is: 1. A device for collecting blood from the skin of a patient, the device comprising a housing having a sampling site, the sampling site defining an opening and having a concave depression, a lancet having a lancet tip adjacent the opening, and a lancet driver operably dispo
The invention claimed is: 1. A device for collecting blood from the skin of a patient, the device comprising a housing having a sampling site, the sampling site defining an opening and having a concave depression, a lancet having a lancet tip adjacent the opening, and a lancet driver operably disposed to the lancet to drive the lancet tip through the opening to lance the skin when the lancet driver is actuated, a sample acquisition module that includes the lancet, a sample chamber and a biosensor, the sample acquisition module being removably coupled to the lancet driver to provide that the sample acquisition module is disposable and the lancet driver is reusable; a manually adjustable penetrating member depth selector positioned at an exterior of the housing, wherein the penetrating member depth selector allows user selection of one of several penetration depth settings to limit penetrating depth of the lancet; the device being configured to allow actuation of the lancet driver, lancing of the skin, collection of the blood, and movement of the blood to the sample reservoir to be integrated. 2. The device of claim 1, wherein the sampling site is adapted to conform to the skin of the patient to form a substantially airtight seal at the opening when the skin is firmly pressed against the sampling site. 3. The device of claim 1, further comprising a sampling port and a pierceable membrane, the sampling port having a first end contiguous with the opening and a second end opposite the first end relatively nearer to the lancet tip than the first end, the pierceable membrane adjacent to the second end between the lancet tip and the opening. 4. The device of claim 3, wherein the membrane is resealable. 5. The device of claim 3, wherein the sampling port has a surface, wherein at least a portion of the sampling port surface is hydrophilic. 6. The device of claim 3, wherein the membrane has a surface, wherein at least a portion of the membrane surface is hydrophobic. 7. The device of claim 1, further comprising at least one capillary channel in fluid communication with the opening and the sample reservoir, the capillary channel having a surface, at least a portion of the capillary channel surface being hydrophilic. 8. The device of claim 7, having at least two capillary channels, wherein at least one of the capillary channels is a primary capillary channel and at least one of the capillary channels is a supplemental capillary channel, each capillary channel having a cross-sectional area, wherein the cross-sectional area of the at least one primary capillary channel is at least twice the cross sectional area of the at least one supplemental capillary channel. 9. The device of claim 1, wherein the device further comprises testing means in fluid communication with the opening. 10. The device of claim 1, wherein the device has dimensions smaller than about 80 mm by 30 mm by 10 mm thick. 11. The device of claim 1, further comprising a backup lancet operably disposed to, the sampling site. 12. The device of claim 1, further comprising a backup lancet having a backup lancet tip, the backup lancet maintained within the housing, the sampling site defining a backup opening adjacent the backup lancet tip, the backup opening in fluid communication with the sample reservoir. 13. The device of claim 1, further comprising a backup reservoir in fluid communication with the sampling site. 14. The device of claim 1, further comprising a backup lancet having a backup lancet tip, the backup lancet maintained within the housing, the sampling site defining a backup opening adjacent the backup lancet tip, the sample acquisition module further comprising a backup reservoir in fluid communication with the backup opening. 15. The device of claim 1, wherein the concave depression is dimensioned to form a substantially air tight seal with a finger tip to allow the blood to be collected without substantial contamination from ambient air. 16. A device for collecting blood from the skin of a patient, the device comprising: a housing having a sampling site, the sampling site defining an opening and having a concave depression; a lancet having a lancet tip adjacent the opening; a lancet driver operably disposed to the lancet to drive the lancet tip through the opening to lance the skin when the lancet driver is actuated; a sample acquisition module that includes the lancet, a sample chamber and a biosensor, the sample acquisition module being removably coupled to the lancet driver to provide that the sample acquisition module is disposable and the lancet driver is reusable; a manually adjustable penetrating member depth selector positioned at an exterior of the housing; the device being configured to allow actuation of the lancet driver, lancing of the skin, collection of the blood, and movement of the blood to the sample reservoir to be integrated and; at least one capillary channel in fluid communication with the opening and the sample reservoir, the capillary channel having a surface, at least a portion of the capillary channel surface being hydrophilic, wherein the sample reservoir comprises a chamber in fluid communication with the opening, the chamber having a perimeter, and a flexible diaphragm attached to the perimeter of the chamber, the flexible diaphragm capable of moving within the chamber under the influence of a pressure source, said movement of the diaphragm serving to facilitate transport of the blood through the at least one capillary channel.
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