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특허 상세정보

Microfluidic pumps and mixers driven by induced-charge electro-osmosis

국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판) G01N-027/453    G01N-027/447   
미국특허분류(USC) 204/450; 204/601; 204/600; 204/451
출원번호 UP-0252871 (2005-10-19)
등록번호 US-7691244 (2010-05-20)
발명자 / 주소
출원인 / 주소
대리인 / 주소
    Pearl Cohen Zedek Latzer, LLP
인용정보 피인용 횟수 : 12  인용 특허 : 25
초록

This invention provides devices and apparatuses comprising the same, for the mixing and pumping of relatively small volumes of fluid. Such devices utilize nonlinear electrokinetics as a primary mechanism for driving fluid flow. Methods of cellular analysis and high-throughput, multi-step product formation using, devices of this invention are described.

대표
청구항

What is claimed is: 1. A microfluidic device comprising one or more inlet ports, one or more outlet ports and microfluidic channels in fluid communication with said ports, said channels comprising one or more micropumps and one or more micromixers, wherein: said micropumps comprise a passageway for transmitting an electrolyte fluid; a source providing an AC or pulsed AC electric field or pulsed AC electric field with a DC offset in said microchannel; at least one conductor element that is placed in an orientation that is perpendicular to the axis of sai...

이 특허에 인용된 특허 (25)

  1. Dasgupta Purnendu K. (Lubbock TX). Apparatus for capillary electrophoresis having an auxiliary electroosmotic pump. USP1997085660703.
  2. Blackburn Gary ; Creager Stephen E. ; Fraser Scott ; Irvine Bruce D. ; Meade Thomas J. ; O'Connor Stephen D. ; Terbrueggen Robert H. ; Vielmetter Jost G. ; Welch Thomas W.. Binding acceleration techniques for the detection of analytes. USP2001076264825.
  3. Hayes, Mark A.; Polson, Nolan A.. Control of flow and materials for micro devices. USP2005056890411.
  4. Van Den Berg, Albert. Device and method for controlling a liquid flow. USP2003016508273.
  5. Ajdari Armand (14 ; rue de Bellechasse 75007 Paris FRX) Lewiner Jacques (7 ; avenue de Suresnes 92210 Saint-Cloud FRX) Prost Jacques (50 ; avenue Ledru Rollin 75012 Paris FRX) Viovy Jean-Louis (26 ; . Devices for separating particles contained in a fluid. USP1997015593565.
  6. Paul Phillip H. ; Rakestraw David J.. Electrokinetic micro-fluid mixer. USP2000076086243.
  7. Zanzucchi Peter John ; Burton Charlotte Anna ; McBride Sterling Edward ; Cherukuri Satyam Choudary ; Chiang William ; Levine Aaron W. ; Moroney ; III Richard Morgan. Electrokinetic pumping. USP1999115985119.
  8. Gordon Gary B. (Saratoga CA). Electrophoresis capillary with dispersion-inhibiting cross-section. USP1994065324413.
  9. Johnson Susan A. ; Lattin Gary A. ; McNichols Larry A.. Electrotransport device and method of setting output. USP2000076086572.
  10. Ghowsi Kiumars (Baton Rouge LA). Field-effect electroosmosis. USP1992035092972.
  11. Backhouse Chris J.,CAX. Fluidic devices. USP2001116318970.
  12. Woudenberg, Timothy M.; Kowallis, Reid B.. High density electrophoresis device and method. USP2003126660147.
  13. Ohkawa, Tihiro. Method for manipulating a solution using a ferroelectric electro-osmotic pump. USP2004106805783.
  14. Jacobson, Stephen C.; Ramsey, J. Michael; Culbertson, Christopher T.; Whitten, William B.; Foote, Robert S.. Methods for forming small-volume electrical contacts and material manipulations with fluidic microchannels. USP2004026685809.
  15. Dubrow Robert S. ; Kennedy Colin B. ; Bousse Luc J.. Microfluidic devices incorporating improved channel geometries. USP2000056068752.
  16. Mpholo,Moeketsi; Brown,Benjamin; Smith,Charles Gordon. Microfluidic movement. USP2006067063778.
  17. Squires,Todd M.; Bazant,Martin Z.. Microfluidic pumps and mixers driven by induced-charge electro-osmosis. USP2006077081189.
  18. Parce J. Wallace ; Knapp Michael R.. Microfluidic sampling system and methods. USP2000036042709.
  19. John Wallace Parce ; Anne R. Kopf-Sill ; Luc J. Bousse. Microfluidic systems. USP2002106465257.
  20. John Wallace Parce ; Anne R. Kopf-Sill ; Luc J. Bousse. Microfluidic systems. USP2002046379974.
  21. John Wallace Parce ; Anne R. Kopf-Sill ; Luc J. Bousse. Microfluidic systems. USP2002096447727.
  22. Kayyem, Jon Faiz. Microfluidic systems in the electrochemical detection of target analytes. USP2005096942771.
  23. John Wallace Parce. Micropump. USP2002056394759.
  24. Mathies Richard A. ; Woolley Adam T.. Miniature reaction chamber and devices incorporating same. USP2000106132580.
  25. Pace Salvatore J. (Wilmington DE). Silicon semiconductor wafer for analyzing micronic biological samples. USP1990034908112.

이 특허를 인용한 특허 피인용횟수: 12

  1. Ducharme, Richard W.; Sugg, David E.. Apparatus and methods for containing and delivering therapeutic agents. USP2013018361054.
  2. Ducharme, Richard W.. Apparatus and methods for delivering therapeutic agents. USP2017129839772.
  3. Liu, Ai Qun; Chin, Lip Ket. Immersion refractometer. USP2016039291547.
  4. Sugioka, Hideyuki. Liquid driver system using a conductor and electrode arrangement to produce an electroosmosis flow. USP2012098272844.
  5. Sugioka, Hideyuki. Liquid mixing apparatus. USP2015129221023.
  6. Wang, Shau-Chun; Chau, Lai-Kwan; Hsieh, Wen-Hsin; Lee, Chia-Yu. Microfluidic device with microstructure, and sensing system and method using same. USP2013018349275.
  7. Klotzkin, David. Simultaneous, single-detector fluorescence detection of multiple analytes with frequency-specific lock-in detection. USP2014058729502.
  8. Ducharme, Richard W. Systems and methods for delivering therapeutic agents. USP2015089101744.
  9. Ducharme, Richard W.; Sugg, David E.; Skelton, Eugene E.; Bruggemann, Martin; Bryce, Lyndsey. Systems and methods for delivering therapeutic agents. USP2016069375533.
  10. Ducharme, Richard W.; Sugg, David E.; Skelton, Eugene; Bruggemann, Martin; Bryce, Lyndsey. Systems and methods for delivering therapeutic agents. USP2014058728032.
  11. Ducharme, Richard W.; Sugg, David E.; Skelton, Eugene; Bruggemann, Martin; Bryce, Lyndsey. Systems and methods for delivering therapeutic agents. USP2012028118777.
  12. Gittard, Shaun D.. Therapeutic agents for delivery using a catheter and pressure source. USP2018019867931.