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Method for producing tissue scaffold having aligned fibrils

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • B29C-047/40
  • B29C-047/20
출원번호 UP-0072167 (2008-02-25)
등록번호 US-7727441 (2010-06-22)
발명자 / 주소
  • Yost, Michael J.
  • Gore, C. Michael
  • Terracio, Louis
  • Goodwin, Richard L.
  • Goldsmith, Edie C.
출원인 / 주소
  • University of South Carolina
대리인 / 주소
    Dority & Manning, P.A.
인용정보 피인용 횟수 : 0  인용 특허 : 45

초록

A tubular tissue scaffold is described which comprises a tube having a wall, wherein the wall includes biopolymer fibrils that are aligned in a helical pattern around the longitudinal axis of the tube where the pitch of the helical pattern changes with the radial position in the tube wall. The scaff

대표청구항

What is claimed is: 1. A method of producing a tubular tissue scaffold, the method comprising: feeding a gel dispersion comprising a biopolymer into an extruder, wherein the extruder has counter-rotating members configured to produce a tube from the gel dispersion while providing a radial shear for

이 특허에 인용된 특허 (45)

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  15. Chang King-Ming,TWX ; Jean Long-Shuenn,TWX ; Liu Yu-Tai,TWX ; Chen Chun-Chieh,TWX ; Chang Ken-Yuan,TWX ; Chiang Shu-Fang,TWX, Highly efficient cell-cultivating device.
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  17. al ; vol. 44 ; No. 4 ; (1993) ; "Cold acclimated buds of Vitis spp. express boiling-stable polypeptides analogous to fish antifreeze proteins"., Implant matrix.
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  42. Tranquillo Robert T. ; Mooradian Daniel L. ; Girton Timothy Sanuel ; Guido Stefano,ITX, Tissue-equivalent rods containing aligned collagen fibrils and schwann cells.
  43. Zilla, Peter Paul; Bezuidenhout, Deon; Dower, Theresa Yvonne, Transmural concentric multilayer ingrowth matrix within well-defined porosity.
  44. Brauker, James Howard; Butters, Leslie Charles; Davidson, Daniel Francis; Ulm, Mark Joseph, Vascular graft with improved flow surfaces.
  45. Fujio Miyawaki JP, Ventricular assist device capable of promoting recovery of cardiac function.
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