초록 ▼

The present invention provides methods and systems for modulating a patient's neurological disease state. In one embodiment, the system comprises one or more sensors that sense at least one signal that comprise a characteristic that is indicative of a neurological disease state. A signal processing

The present invention provides methods and systems for modulating a patient's neurological disease state. In one embodiment, the system comprises one or more sensors that sense at least one signal that comprise a characteristic that is indicative of a neurological disease state. A signal processing assembly is in communication with the one or more sensors and processes the at least one signal to estimate the neurological disease state and to generate a therapy to the patient that is based at least in part on the estimated neurological disease state. A treatment assembly is in communication with the signal processing assembly and delivers the therapy to a nervous system component of the patient.

대표청구항 ▼

What is claimed is: 1. A method of modulating a patient'neurological disease state, the method comprising: sensing at least one neurological signal from the patient; processing the at least one neurological signal using a disease state processor to estimate the neurological disease state; generatin

What is claimed is: 1. A method of modulating a patient'neurological disease state, the method comprising: sensing at least one neurological signal from the patient; processing the at least one neurological signal using a disease state processor to estimate the neurological disease state; generating a therapy output, wherein the generated therapy output is a function of the estimated neurological disease state; delivering the therapy output to the patient; and communicating the estimated neurological disease state to the patient using a patient interface module external to the patient's body. 2. The method of claim 1 wherein delivering the therapy output is carried out with an electrode array. 3. The method of claim 2 further comprising coupling the electrode array to a peripheral nerve. 4. The method of claim 3 wherein the peripheral nerve comprises a vagus nerve. 5. The method of claim 2 further comprising positioning the electrode array intracranially. 6. The method of claim 1 wherein communicating the estimated neurological disease state to the patient comprises displaying of a time history of the estimated neurological disease state. 7. The method of claim 1 wherein said processing the at least one neurological signal using the disease state processor comprises estimating a future neurological disease state. 8. The method of claim 1 wherein sensing is carried out with one or more sensors and processing is carried out with a signal processing assembly, the method comprising implanting the signal processing assembly within the patient's body. 9. The method of claim 1 wherein generating the therapy output is carried out with a control law. 10. A method of modulating a patient'epilepsy disease state, the method comprising: sensing at least one neurological signal from a nervous system component of the patient; processing the at least one neurological signal using a disease state processor to estimate the patient'epilepsy disease state; communicating the patient'estimated epilepsy disease state to the patient using a patient interface module external to the patient'body; generating an electrostimulation therapy output that is based at least in part on the estimated epilepsy disease state; and delivering the electrostimulation therapy output to a vagus nerve of the patient.