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다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
NTIS 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
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Kafe 바로가기국가/구분 | United States(US) Patent 등록 |
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국제특허분류(IPC7판) |
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출원번호 | UP-0504856 (2006-08-16) |
등록번호 | US-7766949 (2010-08-24) |
발명자 / 주소 |
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출원인 / 주소 |
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인용정보 | 피인용 횟수 : 0 인용 특허 : 335 |
A device and method for providing body cooling for treating fever. The cooling device applies cooling to blood flowing in a vein or artery, e.g., the vena cavae, that is then distributed throughout the body.
The invention claimed is: 1. A method for treating fever in a patient's body intravascularly, comprising: providing a catheter having a cooling element attached to a distal end thereof, wherein said cooling element comprises a plurality of heat transfer segments each having a plurality of exterior
The invention claimed is: 1. A method for treating fever in a patient's body intravascularly, comprising: providing a catheter having a cooling element attached to a distal end thereof, wherein said cooling element comprises a plurality of heat transfer segments each having a plurality of exterior surface irregularities being shaped and arranged to create repetitively changing directions of flow in surrounding fluid; inserting the catheter through the vascular system of a patient with a fever to place the cooling element in a vein that drains into the heart of a patient; circulating fluid through the cooling element; transferring heat from the blood in the vein to the cooling element; and thereby lowering the temperature of the patient. 2. The method of claim 1, wherein the surface irregularities each include a helical ridge and a helical groove formed on each heat transfer segment, the helical ridge on each heat transfer segment having an opposite helical twist to the helical ridges on adjacent heat transfer segments. 3. The method of claim 1, wherein each of the plurality of heat transfer segments are connected to adjacent heat transfer segments by a flexible joint. 4. The method of claim 1, further wherein the flexible joint includes a bellows. 5. The method of claim 1, further comprising inducing mixing in the blood of the vascular system of the patient. 6. The method of claim 1, further comprising administering a thermoregulatory drug to the patient. 7. The method of claim 6, wherein the thermoregulatory drug is selected from the group consisting of clonidine, meperidine, propofol, magnesium, dexmedetomidine, and combinations thereof. 8. The method of claim 1, wherein the cooling element is disposed in a vein selected from the group consisting of the superior vena cava, the inferior vena cava, the femoral, the iliac, the subclavian, the braichiocephalic, or combinations of these. 9. A method for determining duration of a intravascular fever treatment, comprising: providing a catheter having a cooling element attached to a distal end thereof, wherein said cooling element comprises a plurality of heat transfer segments each having a plurality of exterior surface irregularities being shaped and arranged to create repetitively changing directions of flow in surrounding fluid; inserting the catheter through the vascular system of a patient with a fever to place the cooling element in a vein that drains into the heart of a patient; circulating fluid through the cooling element, and measuring a starting power withdrawn and starting body temperature at the beginning of the circulating; transferring heat from the blood in the vein to the cooling element, and thereby lowering the temperature of the patient; measuring a power withdrawn and body temperature during the circulating; measuring a power withdrawn at substantially the time when the body temperature equals a normothermic temperature; calculating a Tabsence of cooling from the power withdrawn at substantially the time when the body temperature equals a normothermic temperature, the normothermic temperature, the starting power withdrawn and the starting body temperature; and comparing the Tabsence of cooling with the normothermic temperature, and continuing the circulating if Tabsence of cooling is greater than the normothermic temperature, and discontinuing the circulating if Tabsence of cooling is less than the normothermic temperature. 10. The method of claim 9, wherein the surface irregularities each include a helical ridge and a helical groove formed on each heat transfer segment, the helical ridge on each heat transfer segment having an opposite helical twist to the helical ridges on adjacent heat transfer segments. 11. The method of claim 9, wherein each of the plurality of heat transfer segments are connected to adjacent heat transfer segments by a flexible joint. 12. The method of claim 9, further wherein the flexible joint includes a bellows. 13. A computer program, residing on a computer-readable medium, containing instructions for causing a chiller console, circulating set, and intravascularly inserted catheter having a heat transfer element at a distal end thereof to: circulate fluid through a heat transfer element, wherein said heat transfer element includes a plurality of heat transfer segments each having a plurality of exterior surface irregularities being shaped and arranged to create repetitively changing directions of flow in surrounding fluid, and measuring a starting power withdrawn and starting body temperature corresponding to a body temperature of a patient at the beginning of the circulating; transfer heat from the blood in the vasculature to the heat transfer element, and thereby lowering the body temperature of a patient; measure a power withdrawn and body temperature during the circulating; measure a power withdrawn at substantially the time when the body temperature equals a normothermic temperature; calculate a Tabsence of cooling from: the power withdrawn at substantially the time when the body temperature equals a normothermic temperature, the normothermic temperature, the starting power withdrawn, and the starting body temperature; and compare the Tabsence of cooling with the normothermic temperature, and continuing the circulating if Tabsence of cooling is greater than the normothermic temperature, and discontinuing the circulating if Tabsence of cooling is less than the normothermic temperature. 14. The method of claim 13, wherein the surface irregularities each include a helical ridge and a helical groove formed on each heat transfer segment, the helical ridge on each heat transfer segment having an opposite helical twist to the helical ridges on adjacent heat transfer segments. 15. The method of claim 13, wherein each of the plurality of heat transfer segments are connected to adjacent heat transfer segments by a flexible joint. 16. The method of claim 13, further wherein the flexible joint includes a bellows.
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