Medical fluid pumping system having real time volume determination
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A61M-031/00
A61M-001/00
B01D-011/00
B01D-061/00
출원번호
UP-0773773
(2007-07-05)
등록번호
US-7776006
(2010-09-06)
발명자
/ 주소
Childers, Robert W.
Hopping, Peter A.
출원인 / 주소
Baxter International Inc.
Baxter Healthcare S.A.
대리인 / 주소
K&L Gates LLP
인용정보
피인용 횟수 :
66인용 특허 :
106
초록▼
A medical fluid pumping system includes a medical fluid pump; a first pressure chamber connected fluidly to the medical fluid pump; a second pressure chamber connected fluidly to the medical fluid pump; first and second pressure sensors connected operably to the first and second pressure chambers, r
A medical fluid pumping system includes a medical fluid pump; a first pressure chamber connected fluidly to the medical fluid pump; a second pressure chamber connected fluidly to the medical fluid pump; first and second pressure sensors connected operably to the first and second pressure chambers, respectively; and at least one processor operable with the pressure sensors to calculate a volume of gas in the medical fluid pump prior to a pump-out stroke using a reading from the first pressure sensor after exposing the pump to gas pressure from the first pressure chamber and to use the calculated volume of gas in combination with a known volume of the second pressure chamber and a pressure decay reading taken via the second pressure sensor during the pump-out stroke to calculate at least one volume of fluid pumped during the pump-out stroke.
대표청구항▼
The invention claimed is: 1. A medical fluid pumping system comprising: a medical fluid pump; a first pressure chamber separate from and connected fluidly to the medical fluid pump; a second pressure chamber separate from and connected fluidly to the medical fluid pump; first and second pressure se
The invention claimed is: 1. A medical fluid pumping system comprising: a medical fluid pump; a first pressure chamber separate from and connected fluidly to the medical fluid pump; a second pressure chamber separate from and connected fluidly to the medical fluid pump; first and second pressure sensors connected operably to the first and second pressure chambers, respectively; at least one processor operable with the pressure sensors to calculate a volume of gas in the medical fluid pump prior to a pump-out stroke using a reading from the first pressure sensor after exposing the pump to gas pressure from the first pressure chamber and to use the calculated volume of gas in combination with a known volume of the second pressure chamber and a pressure decay reading taken via the second pressure sensor during the pump-out stroke to calculate at least one volume of fluid pumped during the pump-out stroke; and wherein the medical fluid pump is exposed to gas pressure from the second pressure chamber to perform the pump-out stroke. 2. The medical fluid pumping system of claim 1, wherein the gas is air. 3. The medical fluid pumping system of claim 1, which includes a reference chamber connected fluidly to the medical fluid pump, the reference chamber used to calculate the volume of gas in the medical fluid pump. 4. The medical fluid pumping system of claim 3, which includes a thermal coupling of the medical fluid pump to the reference chamber, tending to make a temperature of gas in the pump at least substantially equal to a temperature of gas in the reference chamber. 5. The medical fluid pumping system of claim 3, which includes at least one valve selected from the group consisting of: (i) a vent valve between the reference chamber and atmosphere; (ii) a valve between the medical fluid pump and the reference chamber; (iii) a valve between the medical fluid pump and the first pressure chamber; and (iv) a valve between the medical fluid pump and the second pressure chamber. 6. The medical fluid pumping system of claim 3, wherein the volume of gas in the medical fluid pump Vgas is calculated according to an equation Vgas=(Pref, final−Pref, initial)/(Ppress1, initial−Ppress1, final)*Vref, wherein (i) Pref,final is a final pressure in the reference chamber after the medical fluid pump is exposed to gas pressure from the first pressure chamber; (ii) Pref,initial is an initial pressure in the reference chamber before the medical fluid pump is exposed to gas pressure from the first pressure chamber; (iii) Ppress1, initial is an initial pressure in the first pressure chamber before the medical fluid pump is exposed to gas pressure from the first pressure chamber; (iv) Ppress1, final is a final pressure in the first pressure chamber after the medical fluid pump is exposed to gas pressure from the first pressure chamber; and (V) Vref is the volume of the reference chamber. 7. The medical fluid pumping system of claim 1, wherein the at least one volume of fluid pumped during the pump-out stroke Vfluid,t is calculated according to an equation Vfluid,t=(Ppress2, initial/Ppress2,t−1)(Vpress2+Vgas), wherein (i) wherein Ppress2,initial is an initial pressure of the second pressure chamber prior to the pump-out stroke; (ii) Ppress2,t is a pressure of the second pressure chamber at a time t during the pump-out stroke; (iii) Vpress2 is a known volume of the second pressure chamber; and (iv) Vgas is the calculated volume of gas in the medical fluid pump. 8. The medical fluid pumping system of claim 1, wherein the medical fluid pump has at least one characteristic selected from the group consisting of: (i) being operated via positive and negative pressures; and (ii) being part of a medical fluid cassette. 9. The medical fluid pumping system of claim 1, wherein the medical fluid pump is a first medical fluid pump, and which includes a second medical fluid pump. 10. The medical fluid pumping system of claim 9, wherein the second medical fluid pump has at least one characteristic selected from the group consisting of: (i) being configured to perform a pump-in stroke when the first medical fluid pump is performing the pump-out stroke; (ii) being operated via positive and negative pressure; (iii) being a membrane pump; (iv) being part of a medical fluid cassette; (v) being connected fluidly to the same first pressure chamber as the first medical fluid pump; (vi) being connected fluidly to a different second pressure chamber as the first medical fluid pump; and (vii) being connected fluidly to a separate reference chamber from a reference chamber connected fluidly to the first fluid pump. 11. The medical fluid pumping system of claim 9, wherein the at least one processor is further configured to calculate a volume of gas in the second medical fluid pump prior to its pump-out stroke and to use the calculated volume of gas during its pump-out stroke to determine at least one partial stroke volume of fluid pumped. 12. The medical fluid pumping system of claim 11, the second medical fluid pump connected fluidly to the first pressure chamber and a third pressure chamber, the third pressure chamber connected operably to a third pressure sensor, the processor using a reading from the first pressure sensor to calculate the volume of gas prior to the second pump-out stroke of the second pump and a reading from the third pressure sensor to calculate the partial stroke fluid volume. 13. The medical fluid pumping system of claim 1, wherein the at least one processor is further configured to calculate a volume of gas in the medical fluid pump after the pump-out stroke using a reading from the first pressure sensor after exposing the pump to gas pressure from the first pressure chamber. 14. The medical fluid pumping system of claim 13, wherein the at least one processor is further configured to calculate a total volume of fluid pumped via the pump-out stroke by subtracting the volume of gas in the medical fluid pump after the pump-out stroke from the volume of gas in the medical fluid pump prior to the pump-out stroke. 15. A medical fluid pumping system comprising: a medical fluid pump; a first pressure chamber separate from and connected fluidly to the medical fluid pump; a second pressure chamber separate from and connected fluidly to the medical fluid pump; first and second pressure sensors connected operably to the first and second pressure chambers, respectively; at least one processor operable with the pressure sensors to calculate a volume of gas in the medical fluid pump prior to a pump-out stroke using a reading from the first pressure sensor after exposing the pump to gas pressure from the first pressure chamber and to use the calculated volume of gas in combination with a known volume of the second pressure chamber and a pressure decay reading taken via the second pressure sensor during the pump-out stroke to calculate at least one volume of fluid pumped during the pump-out stroke; wherein the at least one processor is further configured to: (a) calculate a volume of gas in the medical fluid pump after the pump-out stroke using a reading from the first pressure sensor after exposing the pump to gas pressure from the first chamber; and (b) calculate a total volume of fluid pumped via the pump-out stroke by subtracting the volume of gas in the medical fluid pump after the pump-out stroke from the volume of gas in the medical fluid pump prior to the pump-out stroke; and wherein the total volume of fluid pumped via the pump-out stroke is a first total volume, and which includes a second total volume of fluid pumped calculated by the processor using a final pressure decay reading taken via the second pressure senor, the at least one processor further configured to compare the first and second total fluid volumes pumped via the pump-out stroke. 16. A medical fluid pumping system comprising: a medical fluid pump; a pressure chamber connected fluidly to the medical fluid pump; a pressure sensor connected operably to the pressure chamber; and at least one processor operable with the pressure sensor to calculate at least one volume of fluid pumped during a pump-out stroke Vfluid,t according to an equation Vfluid,t=(Ppress, initial/Ppress,t−1)(Vpress+Vgas), wherein (i) Ppress,initial is an initial pressure of the pressure chamber prior to the pump-out stroke; (ii) Ppress,t is a pressure of the pressure chamber at a time t during the pump-out stroke; (iii) Vpress is a known volume of the pressure chamber; and (iv) Vgas is a volume of gas in the medical fluid pump prior to the pump-out stroke. 17. The medical fluid pumping system of claim 16, the pressure chamber a first pressure chamber, the pressure sensor a first pressure sensor and which includes a second pressure chamber and a second pressure sensor operable with the second pressure chamber, and wherein Vgas is determined using a reading from the second pressure sensor after exposing the pump to gas pressure from the second pressure chamber prior to the pump-out stroke. 18. The medical fluid pumping system of claim 17, the processor further configured to calculate a total volume of fluid pumped using Vgas and a final volume of air in the pressure chamber using a final reading from the second pressure sensor after exposing the pump to gas pressure from the second pressure chamber after the pump-out stroke. 19. The medical fluid pumping system of claim 18, wherein the total volume of fluid pumped via the pump-out stroke is a first total volume, and which includes a second total volume of fluid pumped calculated by the processor using a final pressure decay reading taken via the first pressure senor, the at least one processor further configured to compare the first and second total fluid volumes pumped via the pump-out stroke. 20. The medical fluid pumping system of claim 19, wherein the comparison of the first and second total volumes pumped is used in at least one pumping procedure selected from the group consisting of: (i) determining if a line occlusion has occurred; (ii) determining if air is in the system; (iii) determining fluid flowrate; and (iv) determining if dialysis fluid components have been mixed properly. 21. The medical fluid pumping system of claim 16, wherein the medical fluid pump is exposed to gas pressure from the pressure chamber to perform the pump-out stroke. 22. The medical fluid pumping system of claim 16, the pressure chamber a first pressure chamber, the pressure sensor a first pressure sensor, which includes a second pressure chamber and a second pressure sensor operable with the second pressure chamber, and which includes a reference chamber connected fluidly to the medical fluid pump, and wherein the at least one processor is configured to calculate Vgas according to an equation Vgas=(Pref, final−Pref, initial)/(Ppress1, initial−Ppress1, final)*Vref, wherein (i) Pref,final is a final pressure in the reference chamber after the medical fluid pump is exposed to gas pressure from the second pressure chamber; (ii) Pref,initial is an initial pressure in the reference chamber before the medical fluid pump is exposed to gas pressure from the second pressure chamber; (iii) Ppress1, initial is an initial pressure in the second pressure chamber before the medical fluid pump is exposed to gas pressure from the second pressure chamber; (iv) Ppress1, final is a final pressure in the second pressure chamber after the medical fluid pump is exposed to gas pressure from the first pressure chamber; and (v) Vref is the volume of the reference chamber. 23. The medical fluid pumping system of claim 16, the at least one processor configured to calculate a flowrate by subtracting a volume Vfluid,t at a first time from a volume Vfluid,t at a second time and dividing the difference by the time period from the first time to the second time. 24. A medical fluid pumping system comprising: a medical fluid pump; a pressure chamber connected fluidly to the medical fluid pump; a pressure sensor connected operably to the pressure chamber; and at least one processor operable with the pressure sensor to calculate at least one volume of fluid pumped during a pump-fill stroke Vfluid,t according to an equation Vfluid,t=(Ppress, initial/Ppress,t−1)(Vpress+Vgas), wherein (i) Ppress,initial is an initial negative pressure of the pressure chamber prior to the pump-fill stroke; (ii) Ppress,t is a negative pressure of the pressure chamber at a time t during the pump-fill stroke; (iii) Vpress is a known volume of the pressure chamber; and (iv) Vgas is a volume of gas in the medical fluid pump under negative pressure prior to the pump-fill stroke. 25. The medical fluid pumping system of claim 24, the pressure chamber a first pressure chamber, the pressure sensor a first pressure sensor, which includes a second pressure chamber and a second pressure sensor operable with the second pressure chamber, and wherein Vgas is determined using a negative pressure reading from the second pressure sensor after exposing the pump to negative gas pressure from the second pressure chamber prior to the pump-fill stroke. 26. The medical fluid pumping system of claim 25, the processor further configured to calculate a total volume of fluid pumped using Vgas and a final volume of air in the pressure chamber using a final negative pressure reading from the second pressure sensor after exposing the pump to negative gas pressure from the second pressure chamber after the pump-fill stroke. 27. The medical fluid pumping system of claim 26, wherein the total volume of fluid pumped via the pump-fill stroke is a first total volume, and which includes a second total volume of fluid pumped calculated by the processor using a final negative pressure decay reading taken via the first pressure senor, the at least one processor further configured to compare the first and second total fluid volumes pumped via the pump-fill stroke. 28. The medical fluid pumping system of claim 27, wherein the comparison of the first and second total volumes pumped is used in at least one pumping procedure selected from the group consisting of: (i) determining if a line occlusion has occurred; (ii) determining if air is in the system; and (iii) determining fluid flowrate. 29. The medical fluid pumping system of claim 24, wherein the medical fluid pump is exposed to negative gas pressure from the pressure chamber to perform the pump-fill stroke. 30. The medical fluid pumping system of claim 24, the pressure chamber a first pressure chamber, the pressure sensor a first pressure sensor, which includes a second pressure chamber and a second pressure sensor operable with the second pressure chamber, and which includes a reference chamber connected fluidly to the medical fluid pump, and wherein the at least one processor is configured to calculate Vgas according to an equation Vgas=(Pref, final−Pref, initial)/(Ppress1, initial−Ppress1, final)*Vref, wherein (i) Pref,final is a final negative pressure in the reference chamber after the medical fluid pump is exposed to negative gas pressure from the second pressure chamber; (ii) Pref,initial is an initial pressure in the reference chamber before the medical fluid pump is exposed to negative gas pressure from the second pressure chamber; (iii) Ppress1, initial is an initial negative pressure in the second pressure chamber before the medical fluid pump is exposed to negative gas pressure from the second pressure chamber; (iv) Ppress1, final is a final negative pressure in the second pressure chamber after the medical fluid pump is exposed to negative gas pressure from the first pressure chamber; and (V) Vref is the volume of the reference chamber. 31. The medical fluid pumping system of claim 24, the at least one processor configured to calculate a flowrate by subtracting a volume Vfluid,t at a first time from a volume Vfluid,t at a second time and dividing a resulting difference by a time period from the first time to the second time. 32. The medical fluid pumping system of claim 15, wherein the comparison of the first and second total volumes pumped is used in at least one pumping procedure selected from the group consisting of: (i) determining if a line occlusion has occurred; (ii) determining if air is present in the system; (iii) determining fluid flowrate; and (iv) determining if dialysis fluid components have been mixed properly.
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이 특허에 인용된 특허 (106)
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