초록 ▼

This is a method and an apparatus for the treatment or introduction of contrast fluids into tissue, particularly cardiac tissue. The apparatus includes a catheter having an elongated flexible body and a tissue infusion apparatus including a hollow infusion needle configured to secure the needle into

This is a method and an apparatus for the treatment or introduction of contrast fluids into tissue, particularly cardiac tissue. The apparatus includes a catheter having an elongated flexible body and a tissue infusion apparatus including a hollow infusion needle configured to secure the needle into the tissue when the needle is at least partially inserted into the tissue to help prevent inadvertent removal of the needle from the tissue. This permits the selected treatment or contrast fluid to be confined to a specific site. The catheter may also include a visualization assembly including a transducer at the distal end of the body.

대표청구항 ▼

I claim as my invention: 1. A method for delivering a therapeutic compound to an endocardial delivery site, said method comprising: advancing an elongated catheter body comprising an electrode at a distal end through a blood vessel into a cardiac chamber having the endocardial delivery site to be t

I claim as my invention: 1. A method for delivering a therapeutic compound to an endocardial delivery site, said method comprising: advancing an elongated catheter body comprising an electrode at a distal end through a blood vessel into a cardiac chamber having the endocardial delivery site to be treated; sensing electrical signals originating in the cardiac chamber using a plurality of electrodes on the catheter body to identify the location of the distal end within the cardiac chamber to guide the distal end to the endocardial delivery site; advancing an end of a hollow penetrating structure from the elongated catheter body while in the cardiac chamber into cardiac tissue at the endocardial delivery site; and delivering the therapeutic compound into the tissue at the endocardial delivery site through the hollow penetrating structure. 2. The method as in claim 1, wherein the plurality of electrodes comprise a plurality of ring electrodes on the elongated catheter body. 3. The method as in claim 1, wherein the plurality of electrodes comprise a tip electrode on the catheter body. 4. The method as in claim 1, further comprising steering the catheter to engage the location of the cardiac delivery site. 5. The method as in claim 4, wherein steering comprises pulling cables to steer a distal portion of the catheter body. 6. The method as in claim 1, further comprising securing the end of the hollow penetrating structure into tissue at the cardiac delivery site while the therapeutic compound is being delivered. 7. The method as in claim 6, wherein securing comprises penetrating an element selected from the group consisting of a corkscrew-shaped distal end, a barb, and a pre-curved end of the hollow penetrating structure into tissue at the cardiac delivery site. 8. A method for delivering a therapeutic compound to an endocardial cardiac delivery site, said method comprising: advancing an elongated catheter body through a blood vessel into a cardiac chamber; producing an electrocardiogram to identify a location within the cardiac chamber in need of the therapeutic compound; advancing an end of a hollow penetrating structure from the elongated catheter body while in the cardiac chamber into cardiac tissue at the identified location; and delivering the therapeutic compound into the tissue at the identified location through the hollow penetrating structure at the location.