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T1R3 transgenic animals, cells and related methods 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A01K-067/027
  • A01K-067/00
  • G01N-033/00
  • C12Q-003/00
  • A01N-001/00
  • C12N-005/07
출원번호 UP-0892632 (2004-07-15)
등록번호 US-7803982 (2010-10-21)
발명자 / 주소
  • Margolskee, Robert
  • Rong, Minqing
  • Damak, Sami
출원인 / 주소
  • The Mount Sinai School of Medicine of New York University
대리인 / 주소
    Nixon Peabody LLP
인용정보 피인용 횟수 : 0  인용 특허 : 57

초록 ▼

The present invention relates to the discovery, identification and characterization of a receptor protein, referred to herein as T1R3, which is expressed in taste receptor cells and associated with the perception of bitter and sweet taste. The invention encompasses transgenic animals and cells that

대표청구항 ▼

What is claimed is: 1. A transgenic mouse comprising an endogenous T1R3 gene in the mouse's germ and somatic cells that has been rendered nonfunctional by recombination with a heterologous nucleotide sequence, wherein the mouse (i) is homozygous for nonfunctional endogenous T1R3, (ii) is essentiall

이 특허에 인용된 특허 (57)

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