Methods of inhibiting growth of bacteria, yeast, fungus, and virus with and extracellular products
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A61K-039/00
A61K-039/38
A61K-039/07
A61K-039/108
A61K-008/02
A01N-063/00
A01N-025/34
출원번호
UP-0479064
(2009-06-05)
등록번호
US-7807185
(2010-10-26)
발명자
/ 주소
Farmer, Sean
출원인 / 주소
Ganeden Biotech, Incorporated
대리인 / 주소
Mintz Levin Cohn Ferris Glovsky and Popeo, P.C.
인용정보
피인용 횟수 :
7인용 특허 :
40
초록▼
The present invention discloses compositions derived from an isolated Bacillus species, spores, or an extracellular product of Bacillus coagulans comprising a supernatant or filtrate of a culture of said Bacillus coagulans strain, suitable for topical application to the skin or mucosal membranes of
The present invention discloses compositions derived from an isolated Bacillus species, spores, or an extracellular product of Bacillus coagulans comprising a supernatant or filtrate of a culture of said Bacillus coagulans strain, suitable for topical application to the skin or mucosal membranes of a mammal, which are utilized to inhibit the growth of bacterium, yeast, fungi, virus, and combinations thereof. The present invention also discloses methods of treatment and therapeutic systems for inhibiting the growth of bacterium, yeast, fungi, virus, and combinations thereof, by topical application of therapeutic compositions which are comprised, in part, of isolated Bacillus species, spores, or an extracellular product of Bacillus coagulans comprising a supernatant or filtrate of a culture of said Bacillus coagulans strain. In addition, the present invention also discloses compositions, methods of treatment, and therapeutic systems for inhibiting the growth of bacterium, yeast, fungi, virus, and combinations thereof, comprising an extracellular product of Pseudomonas lindbergii comprising a supernatant or filtrate of a culture of said Pseudomonas lindbergii strain.
대표청구항▼
What is claimed is: 1. A method of inhibiting growth of bacteria, yeast, fungus, or a virus, comprising applying to skin or a mucous membrane of a mammal a composition comprising: an extracellular product of a Pseudomonas lindbergii strain, an extracellular product of a Bacillus coagulans strain, a
What is claimed is: 1. A method of inhibiting growth of bacteria, yeast, fungus, or a virus, comprising applying to skin or a mucous membrane of a mammal a composition comprising: an extracellular product of a Pseudomonas lindbergii strain, an extracellular product of a Bacillus coagulans strain, and an anti-fungal agent selected from the group consisting of Amphotericin B, Carbol-Fuchsin, Ciclopirox, Clotrimzole, Econazole, Haloprogin, Ketoconazole, Mafenide, Miconazole, Naftifine, Nystatin, Oxiconazole, Silver Sulfadiazine, Sulconazole, Terbinafine, Tioconazole, Tolnafiate, and Undecylenic acid, and allowing the composition to contact said skin or mucous membrane for sufficient time to inhibit growth of bacteria, yeast, fungus, or virus. 2. The method of claim 1, wherein said composition comprises approximately 0.5% to approximately 99.9% of said Emu oil, by weight. 3. The method of claim 1, wherein said Bacillus coagulans strain is Bacillus coagulans hammer. 4. The method of claim 1, wherein said Bacillus coagulans strain comprises Bacillus coagulans hammer ATCC Accession Number 31284. 5. The method of claim 1, wherein said composition is in the form of an emulsion, cream, lotion, gel, oil, ointment, aerosol spray, or semi-solid formulation. 6. The method of claim 1, wherein said extracellular product of a Pseudomonas lindbergii strain and said extracellular product of a Bacillus coagulans strain are culture supernatants or filtrates. 7. The method of claim 1, wherein said composition further comprises a carrier, wherein said carrier is selected from the group consisting of trehalose, malto-dextrin, rice flour, micro-crystalline cellulose, magnesium sterate, inositol, fructo-oligosaccharide, gluco-oligosaccharide, dextrose, sucrose, talc, water, physiological salt solution, urea, methanol, ethanol, propanol, butanol, ethylene glycol, propylene glycol, white pertrolatum, isopropyl myristate, lanolin alcohol, mineral oil, lavender oil, nasturtium extract oil, sorbitan mono-oleate, cetylstearyl alcohol, hydroxypropyl cellulose, detergent, sucrose stearate, sucrose cocoate, sucrose distearate, 2-ethyl-1,3-hexanediol, polyoxypropylene-15-stearyl ether, glycerol stearate, glycerin, synthetic spermaceti, cetyl alcohol, butylparaben, propylparaben and methylparaben. 8. The method of claim 1, wherein said extracellular product is a culture supernatant fractionated using a method selected from the group consisting of filtration, liquid chromatography, ion exchange chromatography, and High Performance Liquid Chromatography (HPLC). 9. The method of claim 1, wherein said mammal is a human. 10. The method of claim 1, wherein said composition is applied topically to skin or mucous membrane of a mammal.
연구과제 타임라인
LOADING...
LOADING...
LOADING...
LOADING...
LOADING...
이 특허에 인용된 특허 (40)
Myr-Mkinen Annika (Helsinki FIX) Suomalainen Tarja (Helsinki FIX), Lactobacillus casei ssp. rhamosus, bacterial preparations comprising said strain, and use of said strain and prep.
Ghosh Peter (Fairlight AUX) Whitehouse Michael (Millswood AUX) Dawson Michael (Newton AUX) Turner Athol G. (Forestville AUX), Anti-inflammatory composition derived from emu oil.
Bailly Jean-Claude (Martigues FRX) Bres Philippe (Fos-Sur-Mer FRX) Chabrand Christine (Martigues FRX) Daire Erick (Chateauneuf-Les-Martigues FRX), Catalyst and prepolymer used for the preparation of polyolefins.
Cully Jan (Rosenheim DEX) Vollbrecht Heinz-Rdiger (Altenmarkt DEX), Process for the removal of b
상세보기
Kong Huimin (Beverly MA) Schildkraut Ira (Hamilton MA), Restriction endonuclease obtainable foam bacillus coagulans and a process for producing the same.
Vinopal Robert T. (Mansfield CT) Nelson ; Jr. John D. (Bethlehem CT) Glynn Michael W. (Darien CT) Coughlin Robert W. (Storrs CT) Vieth Robert F. (Manchester CT) Geiger Jon R. (West Hartford CT), Synergistic biocide composition containing pyrithione plus an additive.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.