Methods and systems for modulating acoustic energy delivery
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
B06B-001/00
G01N-029/00
출원번호
UP-0486050
(2009-06-17)
등록번호
US-7811525
(2010-11-01)
발명자
/ 주소
Laugharn, Jr., James A.
Garrison, Brevard S.
McKnight, Robert
Yates, Douglas A.
출원인 / 주소
Covaris, Inc.
대리인 / 주소
Wolf, Greenfield & Sacks, P.C.
인용정보
피인용 횟수 :
7인용 특허 :
72
초록▼
The present invention provides systems, methods, and devices for using acoustic energy. In some embodiments, a fluid bath may be provided in the system where the fluid bath quality may be monitored using acoustic energy. An assessment of fluid bath quality can be determined through a comparison that
The present invention provides systems, methods, and devices for using acoustic energy. In some embodiments, a fluid bath may be provided in the system where the fluid bath quality may be monitored using acoustic energy. An assessment of fluid bath quality can be determined through a comparison that is made of an initial power signal of the acoustic energy with a reflected power signal of the acoustic energy.
대표청구항▼
The invention claimed is: 1. A method for determining fluid bath quality using acoustic energy, the method comprising: providing a fluid bath, the fluid bath having a fluid bath quality; providing at least one sample in a vessel, the vessel being in contact with the fluid bath; generating focused a
The invention claimed is: 1. A method for determining fluid bath quality using acoustic energy, the method comprising: providing a fluid bath, the fluid bath having a fluid bath quality; providing at least one sample in a vessel, the vessel being in contact with the fluid bath; generating focused acoustic energy directed through the fluid bath, the focused acoustic energy having a frequency of between about 100 kilohertz and about 100 megahertz and having a focal zone having a width of less than about 2 centimeters; monitoring an initial power signal from the focused acoustic energy; monitoring a reflected power signal from the focused acoustic energy after the focused acoustic energy is reflected off of a surface; and determining the fluid bath quality based upon a comparison of the initial power signal to the reflected power signal. 2. The method of claim 1, wherein the width corresponds to a diameter of the focal zone. 3. The method of claim 1, wherein the focal zone is cigar-shaped. 4. The method of claim 1, wherein the focal zone is ellipsoidal shaped. 5. The method of claim 1, wherein the focal zone has a width of less than about 1 centimeter. 6. The method of claim 1, wherein the focal zone has a width of less than about 1 millimeter. 7. The method of claim 1, wherein the focused acoustic energy includes multiple focal zones. 8. The method of claim 1, further comprising propagating the focused acoustic energy exterior to the vessel, the focused acoustic energy originating from an acoustic source spaced from and exterior to the vessel. 9. The method of claim 1, wherein the at least one sample comprises a solid. 10. The method of claim 1, wherein the at least one sample comprises a fluid. 11. The method of claim 1, wherein the at least one sample comprises a solid disposed in a solution. 12. The method of claim 1, wherein the fluid bath quality is such that the focused acoustic energy propagates through the fluid bath without cavitation. 13. The method of claim 1, wherein the fluid bath comprises water. 14. The method of claim 1, wherein the fluid bath comprises at least one of ethylene glycol or propylene glycol. 15. The method of claim 1, wherein the fluid bath comprises a mixture of fluids, each fluid having a different freezing temperature. 16. The method of claim 1, further comprising automatically stopping a treatment process after determining that the fluid bath quality is insufficient for processing. 17. The method of claim 1, wherein the surface comprises a surface of the vessel. 18. The method of claim 1, wherein determining the fluid bath quality involves comparing a plateau amplitude of the initial power signal with a plateau amplitude of the reflected power signal. 19. The method of claim 18, further comprising determining a power ratio value of the fluid bath based on calculation of a ratio between the plateau amplitude of the reflected power signal and the plateau amplitude of the initial power signal, wherein the fluid bath is determined to be of a sufficient bath quality if the power ratio value is at least approximately 1.2. 20. The method of claim 18, further comprising determining a figure of merit of the fluid bath based on calculation of a difference between a maximum value observed for the reflected power signal and a minimum value observed for the reflected power signal and dividing the difference by the plateau amplitude of the initial power signal, wherein the fluid bath is determined to be of a sufficient bath quality if the figure of merit is at least approximately 0.8.
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