Cytokine modulators and related method of use
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A61K-036/45
A61K-036/73
A61K-036/906
출원번호
UP-0938093
(2004-09-10)
등록번호
US-7838050
(2011-01-22)
발명자
/ 주소
Randolph, Russell K.
Roh-Schmidt, Haeri
Murray, Mary A.
Crawford, Aaron W.
Gellenbeck, Kevin W.
Pusateri, Donald J.
출원인 / 주소
Access Business Group International LLC
대리인 / 주소
Brinks Hofer Gilson & Lione
인용정보
피인용 횟수 :
7인용 특허 :
45
초록▼
A composition for modulating cytokines to regulate an inflammatory or immunomodulatory response. The composition can include at least one of rosehips, blueberry, blackberry, elderberry, cranberry, rosemary, clove, feverfew, nettle root, artichoke, reishi mushroom, olive extract, green tea extract, g
A composition for modulating cytokines to regulate an inflammatory or immunomodulatory response. The composition can include at least one of rosehips, blueberry, blackberry, elderberry, cranberry, rosemary, clove, feverfew, nettle root, artichoke, reishi mushroom, olive extract, green tea extract, grape seed extract, resveratrol, Aframomum melegueta, boswellia serrata extract, boswellia forte, ipriflavone, tocotrienols, evening primrose oil, INM-176, borage oil, krill oil, at least one type of xanthophyll (e.g., astaxanthin), green coffee extract and ferulic acid. Specifically, a composition of the invention can include: rosehips and at least one of blackberry, blueberry, elderberry, and optionally krill oil; or rosehips, resveratrol and at least one of Aframomum melegueta and astaxanthin. Based on the cytokine modulation and cytokine response inhibition of the composition, it can be used to regulate an immunomodulatory and/or inflammatory response, and subsequently treat diseases and/or abnormal conditions associated with inflammatory response, for example, cardiovascular conditions, arthritis, osteoporosis and Alzheimer's disease.
대표청구항▼
The embodiments of the invention in which an exclusive property or privilege is claimed are defined as follows: 1. A composition comprising a combination of dried rosehips (Rosa canina) or an extract, oil, or powder of rosehips and a dried blueberry (Vaccinium) or an extract or powder of blueberry
The embodiments of the invention in which an exclusive property or privilege is claimed are defined as follows: 1. A composition comprising a combination of dried rosehips (Rosa canina) or an extract, oil, or powder of rosehips and a dried blueberry (Vaccinium) or an extract or powder of blueberry to provide a daily dosage of about 50-5000 rosehips and about 40-2000 mg blueberry wherein the combination inhibits secretion of an interleukin cytokine in a subject; and wherein the composition further comprises at least one of blackberry (Rubus), elderberry (Sambucus), resveratrol, and Aframomum melegueta. 2. The composition of claim 1, wherein the composition further comprises blackberry to provide a daily dosage of about 100-1000 mg blackberry. 3. The composition of claim 1 or claim 2, wherein the composition further comprises resveratrol. 4. The composition of claim 2, wherein the composition further comprises one or more of the following: elderberry, resveratrol, and Aframomum melegueta, and if present to provide a daily dosage of about 200-1000 mg elderberry, about 100-1000 mg resveratrol, and about 150-1500 mg Aframomum melegueta. 5. The composition of claim 1, wherein the composition provides a daily dosage of about 1200 mg rosehips and about 164 mg blueberry. 6. The composition of claim 1, wherein the composition provides a daily dosage of about 1200 mg rosehips and about 330 mg blueberry. 7. The composition of claim 6 further comprising blackberry to provide a daily dosage of about 165 mg blackberry.
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이 특허에 인용된 특허 (45)
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Kharazmi Arsalan,DKX ; Winther Kaj,DKX ; Rein Eydbj.o slashed.rg,DKX, Rose-hip formulations as anti-inflammatory natural medicine for alleviating/reducing symptoms associated with inflammation and arthritis.
Krempin, David W.; Murray, Mary A.; Lin, Yumei; Gellenbeck, Kevin W.; da Costa, Silvia R.; Wilkins, Leon M.; Roh-Schmidt, Haeri; Rana, Jatinder; Rebhun, John F.; Fast, David J., Anti-resorptive and bone building dietary supplements and methods of use.
Katevas, Dimitri Sclabos; Toro Guerra, Raul R.; Chiong Lay, Mario M., Solvent-free process for obtaining phospholipids and neutral enriched krill oils.
Sclabos Katevas, Dimitri; Toro Guerra, Raúl R.; Chiong Lay, Mario M., Solvent-free process for obtaining phospholipids and neutral enriched krill oils.
Sclabos Katevas, Dimitri; Toro Guerra, Raúl R.; Chiong Lay, Mario M., Solvent-free process for obtaining phospholipids and neutral enriched krill oils.
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