초록 ▼

Method and device for the creation of vaccines using ultrasonic waves, comprised of an ultrasound generator and a transducer to produce ultrasonic waves, is disclosed. The transducer has a specific ultrasound tip depending upon the type of delivery method utilized and depending on the shape of the v

Method and device for the creation of vaccines using ultrasonic waves, comprised of an ultrasound generator and a transducer to produce ultrasonic waves, is disclosed. The transducer has a specific ultrasound tip depending upon the type of delivery method utilized and depending on the shape of the vial containing the solution of the virus, bacterium, or other infectious agent. The apparatus delivers ultrasonic waves to solution either directly through the insertion of the ultrasound tip into the solution, through a coupling medium adjacent to the vial or near the vial, or through an air or gas medium. The ultrasound waves have the effect of destroying the viable virus, bacterium, or other infectious agent and of releasing the appropriate antigens, thus resulting in a vaccine for that virus, bacterium, or other infectious agent.

대표청구항 ▼

I claim: 1. An device for creating vaccines comprising: an ultrasound generator driving an ultrasound transducer; the ultrasound transducer having a distal end attached to an ultrasound tip; the ultrasound tip emitting ultrasonic waves at a frequency and an amplitude to produce an ultrasound dosage

I claim: 1. An device for creating vaccines comprising: an ultrasound generator driving an ultrasound transducer; the ultrasound transducer having a distal end attached to an ultrasound tip; the ultrasound tip emitting ultrasonic waves at a frequency and an amplitude to produce an ultrasound dosage; a container for holding a solution with an infectious agent; a central orifice within the ultrasound tip through which solution is added to the container; a means for controlling the ultrasound dosage so that all portions of the solution achieve approximately the same ultrasound dosage; the ultrasound dosage releasing antigens from the infectious agent; and the ultrasound dosage degrading the infectious agent viability. 2. An device for creating vaccines comprising: an ultrasound generator driving an ultrasound transducer; the ultrasound transducer having a distal end attached to an ultrasound tip; the ultrasound tip emitting ultrasonic waves at a frequency and an amplitude to produce an ultrasound dosage; a container for holding a solution with an infectious agent; a central orifice within the ultrasound tip through which solution is added to the container; a means for controlling the ultrasound dosage so that all portions of the solution achieve approximately the same ultrasound dosage; the ultrasound dosage releasing antigens from the infectious agent; and the ultrasound dosage inactivating the infectious agent viability. 3. The device according to claim 1 having a carousel for holding a plurality of containers. 4. The device according to claim 1 having a substantially automated production process. 5. The device according to claim 1 wherein the amplitude of the ultrasonic waves is at least 2 microns. 6. The device according to claim 1 wherein the amplitude of the ultrasonic waves is in the range of 3 to 250 microns. 7. The device according to claim 1 wherein the amplitude of the ultrasonic waves is approximately 80 microns. 8. The device according to claim 1 wherein the frequency of the ultrasonic waves is in the range of 16 kHz to 20 MHz. 9. The device according to claim 1 wherein the frequency of the ultrasonic waves is in the range of 30 kHz to 120 kHz, 10. The device according to claim 1 wherein the frequency of the ultrasonic waves is in the range of approximately 50 kHz. 11. The device according to claim 1 wherein the container may hold at least 0.1 grams of solution. 12. The device according to claim 1 wherein the container may hold between 5 and 10 grams of solution. 13. The device according to claim 1 wherein the ultrasonic energy is delivered for a duration of at least a fraction of a second. 14. The device according to claim 1 wherein the ultrasonic energy is delivered for a duration in the range of 5 to 10 seconds. 15. The device according to claim 1 wherein at least a portion of the ultrasound tip has a distal end shape selected from the group consisting of; a sphere, a rectangular prism, a flat surface, a bulbous and a curved surface. 16. The device according to claim 1 wherein the shape of the ultrasound tip mirrors the shape of the vial in which it is inserted. 17. The device according to claim 1 wherein the frequency is selected from the group consisting of continuous, pulsed and modulated. 18. The device according to claim 1 wherein a driving wave form of the ultrasound transducer is selected from the group consisting of sinusoidal, rectangular, trapezoidal and triangular wave forms.