초록 ▼

Certain embodiments of the invention include forming a material in situ by introducing into a space within a patient a water soluble polymer precursor of at least about 10,000 molecular weight solubilized in a flowable aqueous solution. Functional groups on the polymer precursor undergo covalent bon

Certain embodiments of the invention include forming a material in situ by introducing into a space within a patient a water soluble polymer precursor of at least about 10,000 molecular weight solubilized in a flowable aqueous solution. Functional groups on the polymer precursor undergo covalent bonding in situ to form a solid and nonbiodegradable material having a swellability less than about 20% v/v and a Young's modulus of at least about 100 kPa within about 30 seconds to about 30 minutes of initiating a chemical reaction of the functional groups to form the solid material.

대표청구항 ▼

It is claimed: 1. A method of forming a material in situ in a biocompatible expandable member comprising: increasing a volume of an expandable member of a medical device within a patient by delivering a water soluble polymer precursor in a flowable aqueous solution into the expandable member, wherei

It is claimed: 1. A method of forming a material in situ in a biocompatible expandable member comprising: increasing a volume of an expandable member of a medical device within a patient by delivering a water soluble polymer precursor in a flowable aqueous solution into the expandable member, wherein functional groups on the polymer precursor undergo covalent bonding to form a solid and substantially non biodegradable material having a swellability of less than about 20% v/v and a Young's modulus of at least about 100 kiloPascals within about 30 seconds to about 30 minutes of initiating a chemical reaction of the functional groups to form the solid material.