IPC분류정보
국가/구분 |
United States(US) Patent
등록
|
국제특허분류(IPC7판) |
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출원번호 |
US-0184594
(2005-07-19)
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등록번호 |
US7872095
(2011-01-03)
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발명자
/ 주소 |
- Radhakrishnan, Balasingam
- Aggarwal, Diti
- Ferro, Michelle
- James, Kenneth D.
- Malkar, Navdeep B.
- Miller, Mark A.
- Puskas, Monica
- Ekwuribe, Nnochiri N.
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출원인 / 주소 |
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대리인 / 주소 |
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인용정보 |
피인용 횟수 :
4 인용 특허 :
192 |
초록
▼
An insulin compound coupled to a modifying moiety having a formula:—X—R1—Y-PAG-Z—R (Formula VI)where,X, Y and Z are independently selected linking groups and each is optionally present, and X, when present, is coupled to the insulin compound by a covalent bond,either R1 or R2 is is a lower alkyl, o
An insulin compound coupled to a modifying moiety having a formula:—X—R1—Y-PAG-Z—R (Formula VI)where,X, Y and Z are independently selected linking groups and each is optionally present, and X, when present, is coupled to the insulin compound by a covalent bond,either R1 or R2 is is a lower alkyl, optionally including a carbonyl group, and when R1 is a lower alkyl, R2 is a capping group, andPAG is a linear or branched carbon chain incorporating one or more alkalene glycol moieties, and optionally incorporating one or more additional moieties selected from the group consisting of —S—, —O—, —N—, and —C(O)—, andwhere the modifying moiety has a maximum number of 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, or 25 heavy atoms.
대표청구항
We claim: 1. An insulin compound coupled to a modifying moiety having a formula:—X—R1—Y-PAG-Z—R2 (Formula VI)
We claim: 1. An insulin compound coupled to a modifying moiety having a formula:—X—R1—Y-PAG-Z—R2 (Formula VI)
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