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Detection of nucleic acid sequence differences using the ligase detection reaction with addressable arrays

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • C12Q-001/68
출원번호 US-0725248 (2010-03-16)
등록번호 US7892747 (2011-02-08)
발명자 / 주소
  • Barany, Francis
  • Barany, George
  • Hammer, Robert P.
  • Kempe, Maria
  • Blok, Herman
  • Zirvi, Monib
출원인 / 주소
  • Cornell Research Foundation, Inc.
대리인 / 주소
    Nixon Peabody LLP
인용정보 피인용 횟수 : 9  인용 특허 : 81

초록

The present invention describes a method for identifying one or more of a plurality of sequences differing by one or more single base changes, insertions, deletions, or translocations in a plurality of target nucleotide sequences. The method includes a ligation phase, a capture phase, and a detectio

대표청구항

What is claimed: 1. A method for identifying a plurality of target nucleotide sequences in a sample, said method comprising:providing a sample potentially containing a plurality of target nucleotide sequences;providing a plurality of composite oligonucleotide probes characterized by having a target-

이 특허에 인용된 특허 (81)

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  56. Van Ness Jeffrey ; Tabone John C. ; Howbert J. Jeffry ; Mulligan John T., Methods and compositions for determining the sequence of nucleic acid molecules.
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  78. Barany Francis ; Zebala John ; Nickerson Deborah ; Kaiser ; Jr. Robert J. ; Hood Leroy, Thermostable ligase mediated DNA amplification system for the detection of genetic diseases.
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이 특허를 인용한 특허 (9)

  1. Barany, Francis; Barany, George; Hammer, Robert P.; Kempe, Maria; Blok, Herman; Zirvi, Monib, Detection of nucleic acid sequence differences using the ligase detection reaction with addressable arrays.
  2. Barany, Francis; Barany, George; Hammer, Robert P.; Kempe, Maria; Blok, Herman; Zirvi, Monib, Detection of nucleic acid sequence differences using the ligase detection reaction with addressable arrays.
  3. Barany, Francis; Barany, George; Hammer, Robert P.; Kempe, Maria; Blok, Herman; Zirvi, Monib, Detection of nucleic acid sequence differences using the ligase detection reaction with addressable arrays.
  4. Barany, Francis; Barany, George; Hammer, Robert P.; Kempe, Maria; Blok, Herman; Zirvi, Monib, Detection of nucleic acid sequence differences using the ligase detection reaction with addressable arrays.
  5. Barany, Francis; Barany, George; Hammer, Robert P.; Kempe, Maria; Blok, Herman; Zirvi, Monib, Detection of nucleic acid sequence differences using the ligase detection reaction with addressable arrays.
  6. Etchebarne, Brett Eric, Method of detecting sepsis-related microorganisms and detecting antibiotic-resistant sepsis-related microorganisms in a fluid sample.
  7. Jiang, Zhengwen; Yu, Feng; Li, Caihua, Multiplex nucleic acid analysis.
  8. Vigneault, Francois; Briggs, Adrian Wrangham, Single cell bar-coding for antibody discovery.
  9. Vigneault, Francois; Wrangham Briggs, Adrian, Single cell bar-coding for antibody discovery.
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