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Method and material for enhanced tissue-biomaterial integration

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-031/715
출원번호 US-0369578 (2006-03-07)
등록번호 US7897165 (2011-02-15)
발명자 / 주소
  • Elisseeff, Jennifer
  • Wang, Dong-an
  • Ratcliffe, Anthony
출원인 / 주소
  • Synthasome, Inc.
대리인 / 주소
    Bose McKinney & Evans LLP
인용정보 피인용 횟수 : 5  인용 특허 : 39

초록

The present invention relates to the covalent binding of a hydrogel to an extracellular matrix (ECM). The integration of the hydrogel with the tissue is superior to that in previous techniques. Moreover, unlike previous techniques, the present invention does not require a photoinitiator. Potential t

대표청구항

What is claimed is: 1. A method of integrating a hydrogel to the extracellular matrix of a bone, comprising the steps of:(a) priming the surface of a bone by treating the bone with a priming agent to create a primed bone, wherein the priming agent comprises a polysaccharide with at least one produce

이 특허에 인용된 특허 (39)

  1. Stephen C. Rowe ; Jeffrey A. Hubbell ; Stephen J. Herman ; Vae Sun ; Michael F. Lang ; George E. Selecman ; Frederick F. Ahari, Apparatus and method for local application of polymeric material to tissue.
  2. Re, Paul; Johanson, Mark A.; Marshall, Peter F., Apparatus and method for the repair of articular cartilage defects.
  3. Mansmann Kevin A., Arthroscopic replacement of cartilage using flexible inflatable envelopes.
  4. Swartz Stephen J. (603 Harding Rd. Little Silver NJ 07739), Arthroscopically implantable prosthesis.
  5. Barrera Denise (Oakdale MN) Langer Robert S. (Newton MA) Lansbury ; Jr. Peter T. (Brookline MA) Vacanti Joseph P. (Winchester MA), Biodegradable polymers for cell transplantation.
  6. Pressato, Daniele; Pavesio, Alessandra; Callegaro, Lanfranco, Biomaterials for preventing post-surgical adhesions comprised of hyaluronic acid derivatives.
  7. Simon, Timothy M.; Aberman, Harold M.; Jackson, Douglas W., Cartilage repair plug.
  8. Hubbell, Jeffrey A.; Pathak, Chandrashekhar P.; Sawhney, Amarpreet S.; Desai, Neil P.; Hill, Jennifer L.; Hossainy, Syed F. A., Coating substrates by polymerizing macromers having free radical-polymerizable substituents.
  9. Olof Mikael Trollsas ; Donald G. Wallace ; Frank A. DeLustro, Compositions and systems for forming crosslinked biomaterials and associated methods of preparation and use.
  10. Caplan Arnold I. ; Haynesworth Stephen E., Connective tissue regeneration using human mesenchymal stem cell preparations.
  11. Stephen J. Chudzik ; David L. Clapper, Crosslinkable macromers.
  12. Soon-Shiong Patrick ; Desai Neil P. ; Sandford Paul A. ; Heintz Roswitha A. ; Sojomihardjo Soebianto, Crosslinkable polysaccharides, polycations and lipids useful for encapsulation and drug release.
  13. Melanson David A. ; Levine Marc Alan ; Spiridigliozzi John C. ; Bromander Thomas S. ; Pichon Dean M. ; Selecman George ; Nedder David J., Device for priming for improved adherence of gels to substrates.
  14. Soon-Shiong Patrick (Los Angeles CA) Desai Neil P. (Los Angeles CA) Sandford Paul A. (Los Angeles CA) Heintz Roswitha A. (Los Angeles CA) Sojomihardjo Soebianto (Pasadena CA), Gel compositions prepared from crosslinkable polysaccharides, polycations and/or lipids and uses therefor.
  15. Hubbell Jeffrey A. (Austin TX) Pathak Chandrashekhar P. (Waltham MA) Sawhney Amarpreet S. (Newton MA) Desai Neil P. (Los Angeles CA) Hill-West Jennifer L. (Austin TX) Hossainy Syed F. A. (Austin TX), Gels for encapsulation of biological materials.
  16. Hubbell Jeffrey A. ; Pathak Chandrashekhar P. ; Sawhney Amarpreet S. ; Desai Neil P. ; Hill Jennifer L. ; Hossainy Syed F. A., Gels for encapsulation of biological materials.
  17. Hubbell Jeffrey A. ; Pathak Chandrashekhar P. ; Sawhney Amarpreet S. ; Desai Neil P. ; Hill Jennifer L. ; Hossainy Syed F. A., Gels for encapsulation of biological materials.
  18. Hubbell Jeffrey A. ; Pathak Chandrashekhar P. ; Sawhney Amarpreet S. ; Desai Neil P. ; Hossainy Syed F. A., Gels for encapsulation of biological materials.
  19. Sittinger, Michael; Schultz, Olaf; Burmester, Gerd-Rudiger, Implantable substrates for the healing and protection of connecting tissue, preferably cartilage.
  20. Richard J. Zdrahala ; Ivanka J. Zdrahala, In vivo tissue engineering with biodegradable polymers.
  21. Radice, Marco; Pastorello, Andrea; Pavesio, Alessandra; Callegaro, Lanfranco, Injectable hyaluronic acid derivative with pharmaceuticals/cells.
  22. Hubbell Jeffrey A., Injectable hydrogel compositions.
  23. Li Shu-Tung (Oakland NJ) Stone Kevin R. (Mill Valley CA), Meniscal augmentation device.
  24. Mansmann, Kevin A., Meniscus-type implant with hydrogel surface reinforced by three-dimensional mesh.
  25. Geistlich, Peter; Schloesser, Lothar; Boyne, Phillip J., Method and membrane for mucosa regeneration.
  26. Pathak, Chandrashekhar P.; Barman, Shikha P.; Philbrook, C. Michael; Sawhney, Amarpreet S.; Coury, Arthur J.; Avila, Luis Z.; Kieras, Mark T., Multiblock biodegradable hydrogels for drug delivery and tissue treatment.
  27. Hubbell Jeffrey A. (Austin TX) Pathak Chandrashekhar P. (Waltham MA) Sawhney Amarpreet S. (Newton MA) Desai Neil P. (Los Angeles CA) Hill Jennifer L. (Austin TX), Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers.
  28. Hubbell Jeffrey A. (Austin TX) Pathak Chandrashekhar P. (Waltham MA) Sawhney Amarpreet S. (Newton MA) Desai Neil P. (Los Angeles CA) Hill-West Jennifer L. (Austin TX), Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers.
  29. Hubbell Jeffrey A. ; Pathak Chandrashekhar P. ; Sawhney Amarpreet S. ; Desai Neil P. ; Hill-West Jennifer L., Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers.
  30. Hubbell Jeffrey A. ; Pathak Chandrashekhar P. ; Sawhney Amarpreet S. ; Desai Neil P. ; Hill-West Jennifer L., Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers.
  31. Hubbell, Jeffrey A.; Pathak, Chandrashekhar P.; Sawhney, Amarpreet S.; Desai, Neil P.; Hill, Jennifer L., Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers.
  32. Wallace, Donald G.; Cruise, Gregory M.; Rhee, Woonza M.; Schroeder, Jacqueline Anne; Coker, III, George T.; Maroney, Marcee M.; Trollsas, Olof Mikael, Rapid-gelling biocompatible polymer composition and associated methods of preparation and use.
  33. Langer Robert S. ; Elisseeff Jennifer H. ; Anseth Kristi ; Sims Derek, Semi-interpenetrating or interpenetrating polymer networks for drug delivery and tissue engineering.
  34. Joos, Ulrich, Surface structure for intraosseous implant.
  35. Venkatram R. Shastri ; Ivan Martin ; Robert S. Langer ; Joachim Seidel, Three-dimensional polymer matrices.
  36. Vacanti Charles A. ; Cao Yi Lin ; Langer Robert S. ; Vacanti Joseph P. ; Paige Keith ; Upton Joseph, Tissue engineered tendons and ligaments.
  37. Griffith-Cima Linda ; Atala Anthony ; Vacanti Charles A. ; Paige Keith T., Tissue formation by injecting a cell-polymeric solution that gels in vivo.
  38. Jeffrey A. Hubbell CH; Chandrashekhar P. Pathak ; Amarpreet Sawhney ; Neil Desai ; Syed Hossainy ; Jennifer L. Hill-West, Treating medical conditions by polymerizing macromers to form polymeric materials.
  39. Burns James W. (Holliston MA) Cox Steven (Boston MA) Walts Alan E. (Reading MA), Water insoluble derivatives of hyaluronic acid.

이 특허를 인용한 특허 (5)

  1. Panitch, Alyssa; Paderi, John Eric; Park, Kinam; Stuart, Katherine Allison; Higbee, Steve, Collagen-binding synthetic peptidoglycans, preparation, and methods of use.
  2. Panitch, Alyssa; Paderi, John Eric; Sharma, Shaili; Stuart, Katherine Allison; Vazquez-Portalatin, Nelda Marie, Extracellular matrix-binding synthetic peptidoglycans.
  3. Panitch, Alyssa; Paderi, John Eric; Sharma, Shaili; Stuart, Katherine Allison; Vazquez-Portalatin, Nelda Marie, Extracellular matrix-binding synthetic peptidoglycans.
  4. Panitch, Alyssa; Bernhard, Jonathan C.; Paderi, John E.; Sharma, Shaili, Hyaluronic acid-binding synthetic peptidoglycans, preparation, and methods of use.
  5. Grinstaff, Mark; Cooper, Benjamin Goldman, Injectable tissue supplement.
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