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Fatty acid phenolic conjugates 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • C07H-017/06
출원번호 US-0691816 (2007-03-27)
등록번호 US8008458 (2011-08-15)
발명자 / 주소
  • Zaloga, Gary P.
  • Siddiqui, Rafat
  • Stillwell, William
출원인 / 주소
  • Indiana University Health Inc.
대리인 / 주소
    Woodard, Emhardt, Moriarty, McNett & Henry LLP
인용정보 피인용 횟수 : 17  인용 특허 : 12

초록

This invention relates to a biologically active formulation containing a conjugate of a fatty acid and a complex phenol. The fatty acid can be selected from a variety of fatty acids including acids have between 12 and 24 carbon atoms. The phenol can be a polynuclear phenol, a polyphenol or a polyfun

대표청구항

What is claimed is: 1. A method of treating mammalian cells, the method comprising administering to the cells a pharmaceutical formulation comprising a phenolic ester of a fatty acid in an amount effective to induce cytotoxicity in at least a portion of the cells.

이 특허에 인용된 특허 (12)

  1. Parker Roger A. ; Edwards Michael L. ; Vaal Mark J. ; Matt James E. ; Chen Kim S. ; Yates Mark T. ; Wright Paul S. ; Busch Steven J., Alkyl-4-silylheterocyclic phenols and thiophenols useful as antioxidant agents.
  2. Sakai Takeshi,JPX ; Kitano Hideo,JPX ; Yu Fu-Gong,JPX ; Nakayama Shinji,JPX ; Kojima Kaoru,JPX ; Kimura Hitomi,JPX ; Nakanishi Yoshikuni,JPX ; Katayama Kaoru,JPX ; Tominaga Takanari,JPX ; Shimanaka K, Apoptosis inducers.
  3. Guthrie Najla,CAX ; Kurowska Elzbieta Maria,CAX, Compositions and methods for treatment of neoplastic diseases with combinations of limonoids, flavonoids and tocotrienols.
  4. Perrier Eric,FRX ; Mariotte Anne-Marie,FRX ; Boumendjel Ahcene,FRX ; Bresson-Rival Delphine,FRX, Flavonoide esters and their use notably in cosmetics.
  5. Alvin Guttag, Ibuprofen-aspirin and hydroxymethylacylfulvene analogs.
  6. Weithmann Klaus-Ulrich (Hofheim am Taunus DEX) Wess Gnther (Erlensee DEX) Seiffge Dirk (Mainz DEX), Lipid-selective antioxidants and their preparation and use.
  7. Weithmann Klaus-Ulrich (Hofheim am Taunus DEX) Wess Gnther (Erlensee DEX) Seiffge Dirk (Mainz DEX), Lipid-selective antioxidants and their preparation and use.
  8. Packer Lester ; Tirosh Oren ; Sen Chandan K. ; Roy Sashwati, Lipoic acid analogs.
  9. Mark Empie ; Eric Gugger, Method of preparing and using isoflavones for the treatment of cancer.
  10. Young, Charles, Methods and compositions for inhibiting the proliferation of prostate cancer cells.
  11. Romanczyk ; Jr. Leo J. ; Hammerstone ; Jr. John F. ; Buck Margaret M., Methods of using procyanidin antioxidants.
  12. Uwe Schonrock DE; Heiner Max DE, Use of a content of catechins or a content of green tea extract in cosmetic preparations for tanning the skin.

이 특허를 인용한 특허 (17)

  1. Zemel, Michael; Bruckbauer, Antje; Baggett, Brooke, Compositions and methods for increasing energy metabolism.
  2. Zemel, Michael; Grindstaff, II, E. Douglas; Bruckbauer, Antje, Compositions and methods for modulating metabolic pathways.
  3. Zemel, Michael; Grindstaff, II, E. Douglas; Bruckbauer, Antje, Compositions and methods for modulating metabolic pathways.
  4. Zemel, Michael; Grindstaff, II, E. Douglas; Bruckbauer, Antje, Compositions and methods for modulating metabolic pathways.
  5. Zemel, Michael; Grindstaff, II, E. Douglas; Bruckbauer, Antje, Compositions and methods for modulating metabolic pathways.
  6. Zemel, Michael; Grindstaff, II, E. Douglas; Bruckbauer, Antje, Compositions and methods for modulating metabolic pathways.
  7. Zemel, Michael; Grindstaff, II, E. Douglas; Bruckbauer, Antje, Compositions and methods for modulating metabolic pathways.
  8. Zemel, Michael; Grindstaff, II, E. Douglas; Bruckbauer, Antje, Compositions and methods for modulating metabolic pathways.
  9. Zemel, Michael; Grindstaff, II, E. Douglas; Bruckbauer, Antje, Compositions and methods for modulating metabolic pathways.
  10. Zemel, Michael; Bruckbauer, Antje, Compositions and methods for the reduction or prevention of hepatic steatosis.
  11. Zemel, Michael; Bruckbauer, Antje, Compositions and methods for the reduction or prevention of hepatic steatosis.
  12. Zemel, Michael; Bruckbauer, Antje, Compositions, methods and kits for reducing lipid levels.
  13. Zemel, Michael; Bruckbauer, Antje, Compositions, methods and kits for reducing lipid levels.
  14. Zemel, Michael B.; Grindstaff, II, E. Douglas, Compositions, methods, and kits for regulating energy metabolism.
  15. Zemel, Michael; Grindstaff, II, E. Douglas, Compositions, methods, and kits for regulating energy metabolism.
  16. Zemel, Michael; Grindstaff, II, E. Douglas, Compositions, methods, and kits for regulating energy metabolism.
  17. Zemel, Michael; Grindstaff, II, E. Douglas, Compositions, methods, and kits for regulating energy metabolism.
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