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Metering assembly and method of dispensing fluid

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • F16K-031/00
출원번호 US-0952683 (2007-12-07)
등록번호 US8016260 (2011-08-30)
발명자 / 주소
  • Mukaddam, Kabir James
  • Ezu Hu, Jennifer
  • Stevenson, Jeremy
출원인 / 주소
  • Formulatrix, Inc.
대리인 / 주소
    Wolf, Greenfield & Sacks, P.C.
인용정보 피인용 횟수 : 3  인용 특허 : 76

초록

A metering assembly includes a fluidic chip and metering chambers. Selectable outlet valves communicate with each metering chamber to provide a discrete dispensed volume. The valves may be commonly controlled and may be formed as multi-level valves. The valves may be grouped into common substrate va

대표청구항

What is claimed is: 1. A microfluidic valve comprising:a multi-level unitary elastomeric valve member comprising:a flexible membrane portion having a first membrane thickness;a base membrane portion integrally formed with the flexible membrane portion, the base membrane portion surrounding the flexi

이 특허에 인용된 특허 (76)

  1. Wolk Jeffrey A. ; McReynolds Richard J. ; Parce J. Wallace, Alignment of multicomponent microfabricated structures.
  2. Knapp Michael ; Parce John Wallace ; Bousse Luc J. ; Kopf-Sill Anne R., Closed-loop biochemical analyzers.
  3. Michael Knapp ; John Wallace Parce ; Luc J. Bousse ; Anne R. Kopf-Sill, Closed-loop biochemical analyzers.
  4. Yoshino, Kenro; Hanada, Toshihiro, Constant pressure regulator.
  5. Chow Calvin Y. H. ; Parce John Wallace ; McReynolds Richard J. ; Kennedy Colin B. ; Bousse Luc J., Controller/detector interfaces for microfluidic systems.
  6. Demers Robert Richard, Device for delivering defined volumes.
  7. M체ller Chorus,Birgit; Peters,Ralf Peter; Bartos,Holger, Device for parallel metering of liquids.
  8. Pelrine,Ronald E.; Kornbluh,Roy D., Devices and methods for controlling fluid flow using elastic sheet deflection.
  9. Kopf-Sill, Anne R.; Sundberg, Steven A.; Chow, Andrea W.; Poglitsch, Claudia L., Dilutions in high throughput systems with a single vacuum source.
  10. Paul A. Kearsley ; Tye Fowler ; Barry T. Hixon, Evaporator with hot air bath and method of use.
  11. Chow Andrea W. ; Dubrow Robert S. ; Parce J. Wallace ; Sundberg Steven A. ; Wolk Jeffrey A., External material accession systems and methods.
  12. Kennedy Colin, Fabrication of microfluidic circuits by printing techniques.
  13. Brown,Timothy B.; Kurth,Richard, Flow control of photo-polymerizable resin.
  14. Stehr Manfred,DEX, Fluid pump without non-return valves.
  15. Lee, Michael; Yi, Yong, Fluidic rotary mixer square icon for a display screen.
  16. Lee, Michael; Yi, Yong, Fluidic taper icon for a display screen.
  17. Lee, Ernest C. W.; Nagle, Robert; McReynolds, Richard J.; Chazan, David; Dubrow, Robert S., Fluorescence standard for use in microfluidic instruments.
  18. Wada, H. Garrett; Kopf-Sill, Anne R.; Alajoki, Marja Liisa; Parce, J. Wallace; Wang, Benjamin N.; Chow, Andrea W.; Dubrow, Robert S., Focusing of microparticles in microfluidic systems.
  19. Koehler,Jeffrey A.; Patel,Paren P., Frit material and bonding method for microfluidic separation devices.
  20. Wada, H. Garrett; Sundberg, Steven A., High throughput methods, systems and apparatus for performing cell based screening assays.
  21. Downs, Robert C.; Weselak, Mark R., Massively parallel fluid dispensing systems and methods.
  22. Jensen Morten J., Method and apparatus for measuring low power signals.
  23. Gates James D. ; Pan Jeffrey Y. ; Huang Tung-Ming ; Ver Lee Donald ; Alcock Alan J. ; Li Conan K. N. ; Egan Karen A., Method and apparatus for metering a fluid.
  24. Wolk Jeffrey A., Method of making a capillary for electrokinetic transport of materials.
  25. Moles Donald R., Method of making a fluid flow module.
  26. Parce John Wallace ; Kopf-Sill Anne R., Methods and apparatus for in situ concentration and/or dilution of materials in microfluidic systems.
  27. Dong,Wesley Bryan, Methods and apparatus for minimizing evaporation of sample materials from multiwell plates.
  28. Andrea W. Chow ; Anne R. Kopf-Sill ; Calvin Y. H. Chow, Methods and software for designing microfluidic devices.
  29. Nikiforov Theo T. ; Jeong Sang, Methods and systems for enhanced fluid transport.
  30. Nikiforov, Theo T., Methods and systems for identifying nucleotides by primer extension.
  31. Chien,Ring Ling, Methods and systems for measuring internal dimensions of microscale structures.
  32. Mehta, Tammy Burd, Methods and systems for performing multiple reactions by interfacial mixing.
  33. Nikiforov,Theo T.; Zhou,Aileen, Methods and systems for reducing background signal in assays.
  34. Wolk, Jeffrey A.; Kazakova, Irina; Jensen, Morten J., Methods, systems, and software for performing measurements.
  35. Sasaki Yasuhiko,JPX ; Yoshimura Yasuhiro,JPX ; Koide Akira,JPX ; Miyake Ryo,JPX ; Watanabe Naruo,JPX ; Terayama Takao,JPX ; Mitsumaki Hiroshi,JPX ; Ishida Yasuhiko,JPX ; Morioka Tomonari,JPX, Micro pump and method of producing the same.
  36. Xu,Guolin; Saw,Lin Kiat; Ting,Dor Ngi, Micro-pump.
  37. Okandan, Murat, Microelectromechanical flow control apparatus.
  38. Webster, James Russell, Microfluidic actuator.
  39. Stephen D. O'Connor ; Christoph D. Karp ; Marci Pezzuto ; Eugene Dantsker, Microfluidic branch metering systems and methods.
  40. Michael Knapp ; John Wallace Parce ; Luc J. Bousse ; Anne R. Kopf-Sill, Microfluidic devices and methods for optimizing reactions.
  41. Michael Knapp ; John Wallace Parce ; Luc J. Bousse ; Anne R. Kopf-Sill, Microfluidic devices and methods for separation.
  42. McReynolds,Richard J.; Chazan,David, Microfluidic devices and methods of their manufacture.
  43. Kennedy Colin B., Microfluidic devices and systems.
  44. Unger, Marc A.; Chou, Hou-Pu; Manger, Ian D.; Fernandes, Dave; Yi, Yong, Microfluidic devices for introducing and dispensing fluids from microfluidic systems.
  45. Dubrow Robert S. ; Kennedy Colin B. ; Bousse Luc J., Microfluidic devices incorporating improved channel geometries.
  46. Pezzuto, Marci; O'Connor, Stephen D., Microfluidic devices with porous regions.
  47. Chow Andrea W. ; Kopf-Sill Anne R. ; Parce J. Wallace ; Sundberg Steven A., Microfluidic devices, systems and methods for performing integrated reactions and separations.
  48. Karp,Christoph D., Microfluidic metering systems and methods.
  49. Michael Knapp ; John Wallace Parce ; Luc J. Bousse ; Anne R. Kopf-Sill, Microfluidic methods for non-thermal nucleic acid manipulations.
  50. O'Connor, Stephen D.; Karp, Christoph D., Microfluidic regulating device.
  51. Knapp, Michael; Parce, John Wallace; Bousse, Luc J.; Kopf-Sill, Anne R., Microfluidic sequencing methods.
  52. Chow, Andrea W.; Kopf-Sill, Anne R.; Parce, J. Wallace, Microfluidic systems and methods for determining modulator kinetics.
  53. Michael Knapp ; John Wallace Parce ; Luc J. Bousse ; Anne R. Kopf-Sill, Microfluidic systems and methods of genotyping.
  54. Kopf-Sill Anne R. ; Parce John Wallace, Microfluidic systems incorporating varied channel dimensions.
  55. Sittler Fred C. (Victoria MN) Nelson Cynthia R. (Anoka MN), Micromachined valve with polyimide film diaphragm.
  56. Parce John Wallace, Micropump.
  57. O'Connor, Stephen D.; Karp, Christoph D.; Dantsker, Eugene; Pezzuto, Marci, Modular microfluidic systems.
  58. Kennedy Colin B., Multiplexed microfluidic devices and systems.
  59. Javier A. Farinas, Optical detection of transmembrane potential changes.
  60. Kopf-Sill Anne R. ; Chow Andrea W., Optimized high-throughput analytical system.
  61. Gamble,Ronald C.; Osechinskiy,Sergey I., Parallel fluid processing systems and methods.
  62. J. Wallace Parce ; Andrea W. Chow, Prevention of surface adsorption in microchannels by application of electric current during pressure-induced flow.
  63. Shuck,Gary L., Process for filling microfluidic channels.
  64. McNeely, Michael R.; Spute, Mark K., Remote valving for microfluidic flow control.
  65. Jerman John H. (Palo Alto CA), Semiconductor transducer or actuator utilizing corrugated supports.
  66. Unno,Garrett, Software for the controlled sampling of arrayed materials.
  67. Bardell, Ronald; Weigl, Bernhard H.; Battrell, C. Frederick, Split focusing cytometer.
  68. Tsai Ming-Jye,TWX, Thermally buckling control microvalve.
  69. Chow, Calvin Y. H., Total analyte quantitation.
  70. van Lintel Harald T. G. (Enschede NLX), Valve equipped with a position detector and a micropump incorporating said valve.
  71. Webster Milo E. (Braintree MA), Valve with flexible sheet member.
  72. Webster Milo E. (Braintree MA), Valve with flexible sheet member.
  73. Webster Milo E. (Braintree MA), Valve with flexible sheet member.
  74. Webster Milo E. (Yarmouth Port MA), Valve with flexible sheet member and two port non-flexing backer member.
  75. Chow Calvin Y. H. ; Parce J. Wallace, Variable control of electroosmotic and/or electrophoretic forces within a fluid-containing structure via electrical forc.
  76. Chien,Ring Ling, Voltage/current testing equipment for microfluidic devices.

이 특허를 인용한 특허 (3)

  1. Mukaddam, Kabir; Alimsijah, Pratomo, Fluid delivery system, and associated apparatus and method.
  2. Mathies, Richard A.; Kim, Jungkyu; Jensen, Erik C., Lifting gate polydimethylsiloxane microvalves and pumps for microfluidic control.
  3. Mukaddam, Kabir James; Hu, Jennifer Ezu; Stevenson, Jeremy, Metering assembly and method of dispensing fluid.
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