$\require{mediawiki-texvc}$

연합인증

연합인증 가입 기관의 연구자들은 소속기관의 인증정보(ID와 암호)를 이용해 다른 대학, 연구기관, 서비스 공급자의 다양한 온라인 자원과 연구 데이터를 이용할 수 있습니다.

이는 여행자가 자국에서 발행 받은 여권으로 세계 각국을 자유롭게 여행할 수 있는 것과 같습니다.

연합인증으로 이용이 가능한 서비스는 NTIS, DataON, Edison, Kafe, Webinar 등이 있습니다.

한번의 인증절차만으로 연합인증 가입 서비스에 추가 로그인 없이 이용이 가능합니다.

다만, 연합인증을 위해서는 최초 1회만 인증 절차가 필요합니다. (회원이 아닐 경우 회원 가입이 필요합니다.)

연합인증 절차는 다음과 같습니다.

최초이용시에는
ScienceON에 로그인 → 연합인증 서비스 접속 → 로그인 (본인 확인 또는 회원가입) → 서비스 이용

그 이후에는
ScienceON 로그인 → 연합인증 서비스 접속 → 서비스 이용

연합인증을 활용하시면 KISTI가 제공하는 다양한 서비스를 편리하게 이용하실 수 있습니다.

Method of inducing and/or enhancing an immune response to tumor antigens 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-048/00
출원번호 US-0693754 (2000-10-20)
발명자 / 주소
  • Berinstein, Neil
  • Tartaglia, James
  • Moingeon, Philippe
  • Barber, Brian
출원인 / 주소
  • Sanofi Pasteur Limited
대리인 / 주소
    Patrick J., Halloran
인용정보 피인용 횟수 : 3  인용 특허 : 66

초록

An improved method of inducing and/or enhancing an immune response to a tumor antigen is disclosed. The method involves administering the tumor antigen, nucleic acid coding therefor, vectors and/or cells comprising said nucleic acid, or vaccines comprising the aforementioned to a lymphatic site.

대표청구항

We claim: 1. A method for inducing an immune response to a tumor antigen in a human being comprising administering a tumor antigen in a first form directly into at least one lymph node and subsequently administering the tumor antigen in a second form different from the first form directly into the a

이 특허에 인용된 특허 (66)

  1. Chamberlain Jeffrey S. ; Hartigan-O'Connor Dennis J., Adenovirus vectors.
  2. Chamberlain Jeffrey S. ; Kumar-Singh Rajendra, Adenovirus vectors.
  3. Schlom, Jeffrey; Barzaga, Elene; Zaremba, Sam, Agonist and antagonist peptides of carcinoembryonic antigen (CEA).
  4. Johnston Robert E. ; Davis Nancy L. ; Smith Jonathan F. ; Pushko Peter ; Parker Michael ; Ludwig George, Alphavirus RNA replicon systems.
  5. Dubensky ; Jr. Thomas W. ; Polo John M. ; Ibanez Carlos E. ; Chang Stephen M. W. ; Jolly Douglas J. ; Driver David A., Alphavirus structural protein expression cassettes.
  6. Dubensky ; Jr. Thomas W. ; Polo John M. ; Ibanez Carlos E. ; Chang Stephen M. W. ; Jolly Douglas J. ; Driver David A. ; Belli Barbara A., Alphavirus vector constructs.
  7. Wang Rong-Fu ; Rosenberg Steven A., Alternative open reading frame DNA of a normal gene and a novel human cancer antigen encoded therein.
  8. Wang Rong-Fu ; Rosenberg Steven A., Alternative open reading frame DNA of a normal gene and a novel human cancer antigen encoded therein.
  9. Paoletti Enzo ; Perkus Marion E. ; Taylor Jill ; Tartaglia James ; Norton Elizabeth K. ; Riviere Michel,FRX ; de Taisne Charles,FRX ; Limbach Keith J. ; Johnson Gerard P. ; Pincus Steven E. ; Cox Wil, Alvac canarypox virus recombinants comprising heterlogous inserts.
  10. Wang Rong Fu ; Rosenberg Steven A., Antibodies specific for TRP-2 a human tumor antigen recognized by cytotoxic T lymphocytes.
  11. Levy, John, Avoidance of undesirable replication intermediates in plasmid propagation.
  12. Levy,John, Avoidance of undesirable replication intermediates in plasmid propagation.
  13. Paoletti Enzo ; Tartaglia James ; Cox William I., Canarypox virus expressing cytokine and/or tumor-associated antigen DNA sequence.
  14. Guo, Yajun, Cellular vaccines and immunotherapeutics and methods for their preparation.
  15. Slingluff, Craig L.; Hunt, Donald F.; Engelhard, Victor H.; Kittlesen, David, Cysteine-depleted peptides recognized by A3-restricted cytotoxic lymphocytes, and uses therefor.
  16. Garoff Henrik,SEX ; Liljestrom Peter,SEX, DNA expression systems based on alphaviruses.
  17. Schlom Jeffrey ; Kantor Judith ; Hodge James W., Enhanced immune response to an antigen by a composition of a recombinant virus expressing the antigen with a recombinant virus expressing an immunostimulatory molecule.
  18. Schlom, Jeffrey; Kantor, Judith; Hodge, James W., Enhanced immune response to an antigen by a composition of a recombinant virus expressing the antigen with a recombinant virus expressing an immunostimulatory molecule.
  19. Schlom, Jeffrey; Kantor, Judith; Hodge, James W., Enhanced immune response to an antigen by a composition of a recombinant virus expressing the antigen with a recombinant virus expressing an immunostimulatory molecule.
  20. Simard,John J. L.; Diamond,David C.; Qiu,Zhiyong; Lei,Xiang Dong, Expression vectors encoding epitopes of target-associated antigens and methods for their design.
  21. Rice Charles M. ; Kolykhalov Alexander A., Functional DNA clone for hepatitis C virus (HCV) and uses thereof.
  22. Panicali Dennis L. ; Schlom Jeffrey, Generation of human cytotoxic T-cells specific for carcinoma self-associated antigens and uses thereof.
  23. Panicali Dennis L. ; Schlom Jeffrey, Generation of human cytotoxic T-cells specific for carcinoma self-associated antigens and uses thereof.
  24. Paoletti Enzo (Delmar NY) Perkus Marion E. (Altamont NY), Genetically engineered vaccine strain.
  25. Wang Rong Fu ; Rosenberg Steven A., Identification of TRP-2 as a human tumor antigen recognized by cytotoxic T lymphocytes.
  26. Wang Rong-Fu ; Rosenberg Steven A., Identification of TRP-2 as a human tumor antigen recognized by cytotoxic T lymphocytes.
  27. Paoletti Enzo (Delmar NY) Panicali Dennis (Averill Park NY), Immunogenic composition comprising synthetically modified vaccinia virus.
  28. Paoletti Enzo (Delmar NY) Tartaglia James (Schenectady NY), Interferon sensitive recombinant poxvirus vaccine.
  29. Boon Thierry (Brussels BEX) van der Bruggen Pierre (Brussels BEX) De Plaen Etienne (Brussels BEX) Lurquin Christophe (Brussels BEX) Traversari Catia (Milan ITX), Isolated nonapeptides derived from MAGE genes and uses thereof.
  30. Chen Yao-tseng ; Scanlan Matthew ; Gure Ali ; Old Lloyd J., Isolated nucleic acid molecule encoding an esophageal cancer associated antigen, the antigen itself, and uses thereof.
  31. van den Eynde Benoit,BEX ; van der Bruggen Pierre,BEX ; Boon-Falleur Thierry,BEX, Isolated nucleic acid molecules coding for tumor rejection antigen precursor MAGE-3 and uses thereof.
  32. Boon-Falleur Thierry (Brussels BEX) van der Bruggen Pierre (Brussels BEX) De Plaen Etienne (Brussels BEX) Lurquin Christophe (Brussels BEX) Traversari Catia (Milan ITX) Gaugler Beatrice (Brussels BEX, Isolated nucleic acid molecules which encode MAGE derived nonapeptides.
  33. Topalian, Suzane L.; Rosenberg, Steven A.; Robbins, Paul F., MHC-class II restricted melanoma antigens and their use in therapeutic methods.
  34. Kawakami Yutaka ; Rosenberg Steven A., Melanoma antigens and their use in diagnostic and therapeutic methods.
  35. Kawakami Yutaka ; Rosenberg Steven A., Melanoma antigens and their use in diagnostic and therapeutic methods.
  36. Paoletti Enzo (Delmar NY) Panicali Dennis (Averill Park NY), Method for immunizing animals with synthetically modified vaccinia virus.
  37. Simard, John J. L.; Diamond, David C., Method of epitope discovery.
  38. K?ndig, Thomas M.; Simard, John J. L., Method of inducing a CTL response.
  39. Kundig,Thomas M.; Simard,John L., Method of inducing a CTL response.
  40. K��ndig,Thomas M.; Simard,John J. L., Method of inducing a CTL response.
  41. Cheever Martin A. ; Disis Mary L., Methods for eliciting or enhancing reactivity to HER-2/neu protein.
  42. Paoletti Enzo ; Panicali Dennis, Methods using modified vaccinia virus.
  43. Havermans,Cornelis Christianus Franciscus; Fransen,Renatus Ignatius Jos?phus, Milking installation.
  44. Paoletti Enzo ; Perkus Marion E. ; Taylor Jill ; Tartaglia James ; Norton Elizabeth K. ; Riviere Michel,FRX ; de Taisne Charles,FRX ; Limbach Keith J. ; Johnson Gerard P. ; Pincus Steven E. ; Cox Wil, Modified recombinant vaccinia virus and expression vectors thereof.
  45. Paoletti Enzo (Delmar NY) Panicali Dennis (Averill Park NY), Modified vaccinia virus.
  46. Paoletti Enzo (Delmar NY) Panicali Dennis (Averill Park NY), Modified vaccinia virus and methods for making and using the same.
  47. Paoletti Enzo (Delmar NY) Perkus Marion E. (Altamont NY) Taylor Jill (Albany NY) Tartaglia James (Schenectady NY) Norton Elizabeth K. (Latham NY) Riviere Michel (Ecully FRX) de Taisne Charles (Lyons , NYVAC vaccinia virus recombinants comprising heterologous inserts.
  48. Mekalanos John J. (Framingham MA), Non-toxinogenic vibrio cholerae mutants.
  49. Boon Thierry (Brussels BEX) van der Bruggen Pierre (Brussels BEX) Van den Eynde Benoit (Brussels BEX) Van Pel Aline (Brussels BEX) De Plaen Etienne (Brussels BEX) Lurquin Christophe (Brussels BEX) Ch, Nucleotide sequence encoding the tumor rejection antigen precursor, MAGE-1.
  50. Paoletti, Enzo; Tartaglia, James; Cox, William I., Pox virus comprising DNA sequences encoding CEA and B7 antigen.
  51. Altenburger Werner (Riehen CHX), Recombinant MVA vaccinia virus.
  52. Gregory Richard J. ; Wills Ken N. ; Maneval Daniel C., Recombinant adenoviral vector and methods of use.
  53. Enzo Paoletti, Recombinant avipox virus.
  54. Paoletti Enzo (Albany NY), Recombinant avipox virus and immunological use thereof.
  55. Paoletti Enzo (Delmar NY), Recombinant avipox virus and method to induce an immune response.
  56. Cohen Lawrence K. (Brighton MA) Panicali Dennis L. (Acton MA), Recombinant fowlpox virus and recombination vector.
  57. Panicali, Dennis L.; Bernards, Rene, Recombinant pox virus for immunization against tumor-associated antigens.
  58. Schlom, Jeffrey; Hodge, James; Panicali, Dennis, Recombinant vector expressing multiple costimulatory molecules and uses thereof.
  59. Schlom Jeffrey (Potomac MD) Kantor Judith A. (Rockville MD), Recombinant virus expressing human carcinoembryonic antigen and methods of use thereof.
  60. Dow, Steven W.; Elmslie, Robyn E.; Schwarze, Jurgen Karl Johannes, Systemic immune activation method using nucleic acid-lipid complexes.
  61. Chaux, Pascal; Luiten, Rosalie; Demotte, Nathalie; Duffour, Marie-Therese; Lurquin, Christophe; Traversari, Catia; Stroobant, Vincent; Cornelis, Guy; Boon-Falleur, Thiery; van der Bruggen, Pierre, Tumor antigens and CTL clones isolated by a novel procedure.
  62. Chaux, Pascal; Luiten, Rosalie; Demotte, Nathalie; Duffour, Marie-Therese; Lurquin, Christophe; Traversari, Catie; Stroobant, Vincent; Cornelis, Guy R.; Boon-Falleur, Thierry; van der Bruggen, Pierre, Tumor antigens and CTL clones isolated by a novel procedure.
  63. Rosalie Luiten BE; Marie-Therese Duffour BE; Nathalie Demotte BE; Pierre van der Bruggan BE; Guy Cornelius BE; Vincent Stroobant BE; Christophe Lurquin BE; Thierry Boon-Falleur BE, Tumor antigens and CTL clones isolated by a novel procedure.
  64. Brown Joseph P. (Seattle WA) Estin Charles D. (Bainbridge Island WA) Plowman Gregory D. (Seattle WA) Rose Timothy M. (Seattle WA) Hellstrom Karl E. (Seattle WA) Hellstrom Ingegerd (Seattle WA) Purchi, Vaccines against melanoma.
  65. Bumol Thomas F. (Sportsman J. Richard Carmel IN) Gadski Robert A. (Sportsman J. Richard Indianapolis IN) Hamilton Amy E. (Sportsman J. Richard Indianapolis IN) Sportsiman J. Richard (Sportsman J. Ric, Vectors and DNAS for expression of a human adenocarcinoma antigen.
  66. Tartaglia James ; Cox William I. ; Gettig Russell Robert ; Martinez Hector ; Paoletti Enzo ; Pincus Steven E., Vectors having enhanced expression, and methods of making and uses thereof.

이 특허를 인용한 특허 (3)

  1. Parrington, Mark; Zhang, Linong; Rovinski, Benjamin; Gritz, Linda R.; Greenhalgh, Patricia, Modified CEA nucleic acid and expression vectors.
  2. Jones, Frank R; Gabitzsch, Elizabeth, Replication defective adenovirus vector in vaccination.
  3. Berinstein, Neil; Gallichan, Scott; Lovitt, Corey; Parrington, Mark; Radvanyi, Laszlo; Singh-Sandhu, Devender, Tumor antigens for prevention and/or treatment of cancer.
섹션별 컨텐츠 바로가기

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

AI-Helper 아이콘
AI-Helper
안녕하세요, AI-Helper입니다. 좌측 "선택된 텍스트"에서 텍스트를 선택하여 요약, 번역, 용어설명을 실행하세요.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.

선택된 텍스트

맨위로