초록 ▼

Methods and systems to perform point-of-care, user-initiated fluidic assays, using substantially self-contained, portable, user-initiated fluidic assay systems. Exemplary assays include diagnostic assays and chemical detection assays. Diagnostic assays may include, without limitation, enzyme-linked

Methods and systems to perform point-of-care, user-initiated fluidic assays, using substantially self-contained, portable, user-initiated fluidic assay systems. Exemplary assays include diagnostic assays and chemical detection assays. Diagnostic assays may include, without limitation, enzyme-linked immuno-sorbent assays (ELISA), and may include one or more sexually transmitted disease (STD) diagnostic assays. An exemplary assay system includes a housing having one or more fluid chambers, a fluid controller system to dispense fluid from the one or more fluid chambers, and a user-initiated actuator to control the fluid controller system. The actuator may be configured to move fluid controllers from functionally closed positions to functionally open positions, to control fluid flow from the fluid chambers. The fluid controller system may be configured to dispense fluids serially, and may be configured to mix a plurality of fluids. The housing may include one or more fluid paths amongst the fluid chambers and/or between the fluid chambers and an assay portion, and the fluid controller system may be configured to serially align fluid chamber outlets with corresponding fluid paths. The user-initiated actuator system may include an external user-operated trigger mechanism to initiate the actuator system. The actuator system may include a mechanical actuator system, and may include a compressible spring actuator system. The assay apparatus may include a display window to view assay results. Exemplary methods of preparing portable, user-initiated fluidic assay systems, and methods of using portable, user-initiated fluidic assay systems are disclosed.

대표청구항 ▼

What is claimed is: 1. A portable, point-of-care assay system, comprising:a portable housing having a sample portion, an assay portion, a sample fluid passage between a fluid outlet of the sample portion and a fluid inlet of the assay portion, and a plurality of fluid chambers, each of the plurality

What is claimed is: 1. A portable, point-of-care assay system, comprising:a portable housing having a sample portion, an assay portion, a sample fluid passage between a fluid outlet of the sample portion and a fluid inlet of the assay portion, and a plurality of fluid chambers, each of the plurality of fluid chambers having a fluid chamber outlet;a fluid controller system separating the plurality of fluid chambers and movably disposed within the housing to align each of the plurality of fluid chamber outlets with a corresponding fluid path to one or more of another one of the fluid chambers, the sample portion, and the assay portion; anda user-initiated mechanical actuator coupled to the fluid controller system.