초록 ▼

Disclosed herein is an analyte sensing biointerface that comprises a sensing electrode incorporated within a non-conductive matrix comprising a plurality of passageways extending through the matrix to the sensing electrode. Also disclosed herein are methods of manufacturing a sensing biointerface an

Disclosed herein is an analyte sensing biointerface that comprises a sensing electrode incorporated within a non-conductive matrix comprising a plurality of passageways extending through the matrix to the sensing electrode. Also disclosed herein are methods of manufacturing a sensing biointerface and methods of detecting an analyte within tissue of a host using an analyte sensing biointerface.

대표청구항 ▼

What is claimed is: 1. A glucose sensor configured for implantation in a host, comprising:a biocompatible matrix comprising a plurality of passageways distributed throughout the biocompatible matrix, each of the plurality of passageways having interior surfaces;a working electrode distributed throug

What is claimed is: 1. A glucose sensor configured for implantation in a host, comprising:a biocompatible matrix comprising a plurality of passageways distributed throughout the biocompatible matrix, each of the plurality of passageways having interior surfaces;a working electrode distributed throughout at least some of the interior surfaces of the plurality of passageways; anda membrane disposed on the working electrode and distributed within the interior surfaces of the plurality of passageways, and wherein the membrane is configured to control a rate of diffusion of glucose through the membrane, and wherein the membrane comprises an enzyme configured to react with glucose to produce a species configured to electrochemically react at the working electrode.