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Solid micro-perforators and methods of use 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • B29C-041/46
출원번호 US-0528059 (2003-09-15)
등록번호 US8062573 (2011-11-07)
국제출원번호 PCT/US03/30881 (2003-09-15)
§371/§102 date 20050315 (20050315)
국제공개번호 WO04/024224 (2004-03-25)
발명자 / 주소
  • Kwon, Sung-Yun
출원인 / 주소
  • TheraJect, Inc.
대리인 / 주소
    Sherr & Vaughn, PLLC
인용정보 피인용 횟수 : 25  인용 특허 : 50

초록

Porous microperforators (210A), preferably in an array of multiple perforators are employed for delivery of a drug, where the micro-perforators may dissolve in situ. Suitable micro-perforators may include multiple layers of dissolvable materials to effect sequential drug delivery. In further aspects

대표청구항

What is claimed is: 1. A method of manufacture of a micro-perforator, comprising:providing a solidifiable material, and forming the solidifiable material, optionally in admixture with a diagnostic or therapeutic agent into a desired micro-perforator shape;wherein the step of forming the solidifiable

이 특허에 인용된 특허 (50)

  1. Cox Brian J. (10191 Lebanon Dr. Cupertino CA 95014), Anal patch for fecal incontinence.
  2. Sherman Faiz Feisal ; Yuzhakov Vadim Vladimirovich ; Gartstein Vladimir ; Owens Grover David, Apparatus and method for manufacturing an intracutaneous microneedle array.
  3. Yuzhakov Vadim Vladimirovich ; Sherman Faiz Feisal ; Owens Grover David ; Gartstein Vladimir, Apparatus and method for using an intracutaneous microneedle array.
  4. Leighton Stephen B. (Maplewood NJ) Brownstein Michael J. (Rockville MD), Array-type multiple cell injector.
  5. Nelson Charles W., Attachment unit for hair replacement.
  6. Dunn Richard L. ; English James P. ; Cowsar Donald R. ; Vanderbilt David P., Biodegradable in-situ forming implants and methods of producing the same.
  7. Thomas Buch-Rasmussen DK; S?ren Aasmul DK; James M. Flink DK; Philip Hansen DK; Claus Juul-Mortensen DK; Jens Ulrik Poulsen DK, Cassette for storing and insertion of solid medicine.
  8. Jonathan A. Eppstein ; Michael R. Hatch ; Joseph Papp ; Mark L. Faupel ; Krishna Kumar, Controlled removal of biological membrane by pyrotechnic charge for transmembrane transport.
  9. Julian A. Blair GB, Derivatized carbohydrates, compositions comprised thereof and methods of use thereof.
  10. Cormier Michel J. N. ; Theeuwes Felix T., Device and method for enchancing transdermal sampling.
  11. Cormier Michel J. N. ; Nat Avtar S. ; Neukermans Armand P. ; Block Barry, Device for enhancing transdermal agent delivery or sampling.
  12. Trautman Joseph Creagan ; Cormier Michel J. N. ; Kim Hyunok Lynn ; Zuck Michael G., Device for enhancing transdermal agent flux.
  13. Trautman Joseph Creagan ; Wong Patrick S.-L. ; Daddona Peter E. ; Kim Hyunok Lynn ; Zuck Michael G., Device for enhancing transdermal agent flux.
  14. Zuck Michael G., Device for enhancing transdermal agent flux.
  15. Prausnitz, Mark R.; Allen, Mark G.; Henry, Sebastien; McAllister, Devin V.; Ackley, Donald E.; Jackson, Thomas, Devices and methods for enhanced microneedle penetration of biological barriers.
  16. Roser Bruce Joseph,GBX, Disposable injector device.
  17. Gerstel Martin S. (Palo Alto CA) Place Virgil A. (Palo Alto CA), Drug delivery device.
  18. Panoz Donald E. (Athlone IEX), Drug delivery device.
  19. Eppstein Jonathan A. (Atlanta GA) Eppstein Deborah A. (Salt Lake City UT) Kost Joseph (Omer MA ILX) Langer Robert S. (Newton MA), Enhancement of transdermal monitoring applications with ultrasound and chemical enhancers.
  20. Lebouitz Kyle S. ; Pisano Albert P., Epidermal abrasion device with isotropically etched tips, and method of fabricating such a device.
  21. Simon Robert J. (West Carrolton OH) Rudolf Daniel R. (Yellow Springs OH) Katerberg James A. (Kettering OH) Pipkorn David N. (Centerville OH), Four inch print head assembly.
  22. Lin Liwei (Berkeley CA) Pisano Albert P. (Berkeley CA), IC-processed microneedles.
  23. Lin Liwei ; Pisano Albert P., IC-processed microneedles.
  24. John Willis ; Thaddeus Minior ; Robert Gonnelli, Injection devices.
  25. Vladimir Gartstein ; Dragan Danilo Nebrigic ; Grover David Owens ; Faiz Feisal Sherman ; Vadim Vladimirovich Yuzhakov, Intracutaneous microneedle array apparatus.
  26. Gross Joseph (Rathgar IEX) Kelly John G. (Rathgar IEX), Intradermal drug delivery device and method for intradermal delivery of drugs.
  27. Gross Joseph,IEX ; Kelly John Gerard,IEX, Intradermal drug delivery device and method for intradermal delivery of drugs.
  28. Haaga John R. (3409 N. Hilltop Chagrin Falls OH 44022), Medical needle with bioabsorbable tip.
  29. Godshall Ned Allen ; Anderson R. Rox, Method and apparatus for disruption of the epidermis.
  30. Jarvis Eric E. (Boulder CO), Method for fabricating a substrate having spaced apart microcapillaries thereon.
  31. Talbot Neil H. ; Keller Christopher G. ; Pisano Albert P., Method for fabricating needles via conformal deposition in two-piece molds.
  32. Drew J. Buoni ; Alan R. Kaufman, Method for forming multi-layer laminates with microstructures.
  33. Alexander G. Lastovich ; John D. Evans ; Ronald J. Pettis, Microdevice and method of manufacturing a microdevice.
  34. Mark G. Allen ; Mark R. Prausnitz ; Devin V. McAllister ; Florent Paul Marcel Cros, Microneedle devices and methods of manufacture and use thereof.
  35. Prausnitz, Mark R.; Allen, Mark G.; Gujral, Inder-Jeet, Microneedle drug delivery device.
  36. Pisano Albert P. ; Lebouitz Kyle S., Microneedle with isotropically etched tip, and method of fabricating such a device.
  37. Eppstein Jonathan A. ; Hatch Michael R. ; Yang Difei, Microporation of human skin for drug delivery and monitoring applications.
  38. Daddona Peter E. ; Fieldson Gregory T. ; Nat Avtar S. ; Lin Wei-Qi, Minimally invasive detecting device.
  39. Chacornac ; Georges, Multi-penetration vaccination apparatus.
  40. Ginaven Robert O. (Encinitas CA) Facciotti Daniel (Davis CA), Needle array and method of introducing biological substances into living cells using the needle array.
  41. Sarath Alan (Teaneck NJ) Mawhirt James A. (Brooklyn NY), Needle cartridge.
  42. Bellhouse Brian John,GBX ; Drayson Paul Rudd,GBX ; Greenford John Christopher,GBX ; Sarphie David Francis,GBX, Particle delivery.
  43. Powell Kenneth G. ; Monahan Larry A. ; Sage ; Jr. Burton H., Process of making a molded device.
  44. Lawson Alexis A. ; Lawson Michael, Skin penetration apparatus including multiple needle configuration.
  45. Jang Kwang Kyun,KRX, Skin perforating apparatus for transdermal medication.
  46. Roser Bruce J.,GBX ; Kampinga Jaap,NLX ; Colaco Camilo,GBX ; Blair Julian,GBX, Solid dose delivery vehicle and methods of making same.
  47. Kamen Dean L., System for delivery of drugs by transport.
  48. Eicher Joachim,DEX ; Zierenberg Bernd,DEX, Transcorneal drug-release system.
  49. Lee Hai Bang (Taejeon KRX) Shin Bung Chul (Taejeon KRX), Transdermal administration method of protein or peptide drug and its administration device thereof.
  50. Gross Joseph (Moshav Mazor ILX) Zucker Shlomo (Mihmoret ILX), Transdermal or interdermal drug delivery devices.

이 특허를 인용한 특허 (25)

  1. Corrie, Simon Robert; Kendall, Mark Anthony Fernance, Analyte detection using a needle projection patch.
  2. Liu, Qingchun; Wei, Zhenli, Catalyst compositions and their use for hydrogenation of nitrile rubber.
  3. Liu, Qingchun; Wei, Zhenli, Catalyst compositions and their use for hydrogenation of nitrile rubber.
  4. Kendall, Mark Anthony Fernance; Fernando, Germain; Chen, Xianfeng; Prow, Tarl, Coating method.
  5. Kendall, Mark Anthony Fernance; Fernando, Germain; Chen, Xianfeng; Prow, Tarl, Coating method.
  6. Engqvist, Hakan, Composition for sustained drug delivery comprising geopolymeric binder.
  7. Kendall, Mark Anthony Fernance, Delivery device.
  8. Gharib, Morteza; Aria, Adrianus I.; Sansom, Elijah Bodhi, Drug delivery and substance transfer facilitated by nano-enhanced device having aligned carbon nanotubes protruding from device surface.
  9. Gharib, Morteza; Aria, Adrianus I.; Sansom, Elijah Bodhi, Drug delivery and substance transfer facilitated by nano-enhanced device having aligned carbon nanotubes protruding from device surface.
  10. Sansom, Elijah Bodhi; Gharib, Morteza; Rinderknecht, Derek, Fabrication of anchored carbon nanotube array devices for integrated light collection and energy conversion.
  11. Aria, Adrianus Indrat; Gharib, Morteza; Gani, Adi Wijaya, Method for producing graphene oxide with tunable gap.
  12. Kendall, Mark Anthony Fernance, Method of delivering material or stimulus to a biological subject.
  13. Oh, Sea-Jin; Kwon, Sung-Yun, Method of manufacturing solid solution perforator patches and uses thereof.
  14. Aria, Adrianus Indrat; Lyon, Bradley; Gharib, Morteza, Method to increase the capacitance of electrochemical carbon nanotube capacitors by conformal deposition of nanoparticles.
  15. Le, Anthony; Bourne, Doug; Shastry, Ashutosh; Worsham, Robert Wade; Singh, Parminder, Microprojection applicators and methods of use.
  16. Bourne, Doug; Shastry, Ashutosh; Le, Anthony; Singh, Parminder, Multiple impact microprojection applicators and methods of use.
  17. Lyon, Bradley; Aria, Adrianus I.; Gharib, Morteza, Nano tri-carbon composite systems and manufacture.
  18. Kendall, Mark Anthony Fernance; Ansaldo, Alexander Bernard; Crichton, Michael Lawrence; Falconer, Robert John, Patch applying apparatus.
  19. Kendall, Mark Anthony Fernance; Jenkins, Derek William Kenneth, Patch production.
  20. Kendall, Mark Anthony Fernance; Jenkins, Derek William Kenneth, Patch production.
  21. Aria, Adrianus I.; Lyon, Bradley; Gharib, Morteza, Sharp tip carbon nanotube microneedle devices and their fabrication.
  22. Aria, Adrianus I.; Beizai, Masoud; Gharib, Morteza, Simple method for producing superhydrophobic carbon nanotube array.
  23. Singh, Parminder; Worsham, Robert Wade; Trautman, Joseph C.; Bayamov, Danir; Bowers, Danny Lee; Klemm, Andrew Richard; Klemm, Steven Richard; Chen, Guohua, Solvent-cast microprotrusion arrays containing active ingredient.
  24. Falo, Jr., Louis D.; Erdos, Geza; Ozdoganlar, O. Burak, Tip-loaded microneedle arrays for transdermal insertion.
  25. Engqvist, Håkan; Bredenberg, Susanne; Pettersson, Anders; Lundqvist, Thomas; Dahlgren, Anna; Sågström, Anders, Transdermal drug administration device.
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