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Kafe 바로가기국가/구분 | United States(US) Patent 등록 |
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국제특허분류(IPC7판) |
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출원번호 | US-0697079 (2007-04-05) |
등록번호 | US8067054 (2011-11-16) |
발명자 / 주소 |
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출원인 / 주소 |
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대리인 / 주소 |
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인용정보 | 피인용 횟수 : 4 인용 특허 : 436 |
A method of making a drug eluting stent comprises forming a porous stent body surface layer by ion implantation, applying a layer of ceramic particles on the porous layer and compressing the layer of ceramic particles. The layer of ceramic particles can be compressed to successively higher densities
A method of making a drug eluting stent comprises forming a porous stent body surface layer by ion implantation, applying a layer of ceramic particles on the porous layer and compressing the layer of ceramic particles. The layer of ceramic particles can be compressed to successively higher densities. Drugs can be loaded into the layer of ceramic materials at a relatively low density before the layer of ceramic materials is compressed to a higher density to achieve a desired low drug release rate.
I claim: 1. A method of making a stent, the method comprising steps of:implanting at least one type of ion into a metallic stent body material in at least one surface portion of the stent body material to produce at least one porous layer at the surface portion, the at least one porous layer compris
I claim: 1. A method of making a stent, the method comprising steps of:implanting at least one type of ion into a metallic stent body material in at least one surface portion of the stent body material to produce at least one porous layer at the surface portion, the at least one porous layer comprising a plurality of open pores with a first average size for at least 50 volume percent of the open pores;depositing a layer of ceramic particles on the porous layer, the ceramic particles having a second average size for at least 50 volume percent of the ceramic particles, the second average size being smaller than one tenth of the first average size; andcompressing the layer of ceramic particles to form a plurality of protuberances and/or recesses on a surface of the layer of ceramic particles, wherein compressing the layer of ceramic particles comprises compressing using a solid surface having a plurality of protuberances and/ or recesses.
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