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Nucleic acid agents for downregulating H19 and methods of using same 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • C07H-021/04
출원번호 US-0994810 (2006-07-06)
등록번호 US8067573 (2011-11-16)
국제출원번호 PCT/IL2006/000785 (2006-07-06)
§371/§102 date 20080708 (20080708)
국제공개번호 WO07/007317 (2007-01-18)
발명자 / 주소
  • Hochberg, Avraham
  • Matouk, Imad
출원인 / 주소
  • Yissum Research Development Company of the Hebrew University of Jerusalem
대리인 / 주소
    Winston & Strawn LLP
인용정보 피인용 횟수 : 0  인용 특허 : 73

초록 ▼

The present invention provides isolated oligonucleotides capable of down-regulating a level of H19 mRNA in cancer cells. Articles of manufacture comprising agents capable of downregulating H19 mRNA in combination with an additional anti-cancer treatment are disclosed as well as methods of treating c

대표청구항

What is claimed is: 1. An isolated oligonucleotide able to down-regulate H19 mRNA under both normal and hypoxic conditions as set forth in SEQ ID NO: 1.

이 특허에 인용된 특허 (73)

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