IPC분류정보
국가/구분 |
United States(US) Patent
등록
|
국제특허분류(IPC7판) |
|
출원번호 |
US-0731882
(2007-03-30)
|
등록번호 |
US-8088157
(2012-01-03)
|
우선권정보 |
DE-198 40 645 (1998-09-05) |
발명자
/ 주소 |
- Fierens, Joost J.
- Schaffner, Silvio R.
- Gianotti, Marc
- Seibold, Gerd
- Von Oepen, Randolf
|
출원인 / 주소 |
- Abbott Laboratories Vascular Enterprises Limited
|
대리인 / 주소 |
|
인용정보 |
피인용 횟수 :
3 인용 특허 :
212 |
초록
▼
Apparatus and methods for stenting are provided comprising a stent attached to a porous biocompatible material that is permeable to endothelial cell ingrowth, but impermeable to release of emboli of predetermined size. Preferred stent designs are provided, as well as preferred manufacturing techniqu
Apparatus and methods for stenting are provided comprising a stent attached to a porous biocompatible material that is permeable to endothelial cell ingrowth, but impermeable to release of emboli of predetermined size. Preferred stent designs are provided, as well as preferred manufacturing techniques. Apparatus and methods are also provided for use at a vessel branching. Moreover, embodiments of the present invention may comprise a coating configured for localized delivery of therapeutic agents. Embodiments of the present invention are expected to provide enhanced embolic protection, improved force distribution, and improved recrossability, while reducing a risk of restenosis and thrombus formation.
대표청구항
▼
1. A covered endoprosthesis comprising: a generally tubular member having inner and outer surfaces defining a wall, a pattern within the wall defining a web structure configured for expansion from a collapsed position to an expanded position; anda membrane disposed about at least a portion of the tu
1. A covered endoprosthesis comprising: a generally tubular member having inner and outer surfaces defining a wall, a pattern within the wall defining a web structure configured for expansion from a collapsed position to an expanded position; anda membrane disposed about at least a portion of the tubular member, a plurality of pores being formed in the membrane, at least some of the pores having a maximum width of about 100 um to reduce release of emboli larger than a predetermined size from the wall into a lumen upon expansion of the tubular member into the lumen from the collapsed position to the expanded position and having a minimum width to enable endothelial cell ingrowth. 2. The covered endoprosthesis according to claim 1, wherein the membrane is formed by a weaving, knitting or braiding process. 3. The covered endoprosthesis according to claim 1, wherein the pores have a minimum width of approximately 30 μm or more. 4. The covered endoprosthesis of claim 1, wherein the membrane further includes a coating. 5. The covered endoprosthesis of claim 4, wherein the coating comprises a therapeutic agent. 6. The covered endoprosthesis according to claim 1, wherein the membrane is disposed about at least a portion of the outer surface of the tubular member. 7. The covered endoprosthesis according to claim 6, wherein the membrane is further disposed about at least a portion of the inner surface of the tubular member. 8. The covered endoprosthesis according to claim 1, wherein one or more of the plurality of pores is sized to allow blood flow therethrough. 9. The covered endoprosthesis according to claim 8, further including a radial opening formed in the web pattern, wherein at least one of the one or more pores sized to allow blood flow therethrough are positioned within the radial opening. 10. The covered endoprosthesis according to claim 1, wherein the tubular member is self-expanding. 11. The covered endoprosthesis according to claim 1, wherein the tubular member is balloon expandable. 12. The covered endoprosthesis according to claim 1, wherein the pores formed in the membrane are uneven in size and placement. 13. A covered endoprosthesis comprising: a generally tubular member having inner and outer surfaces defining a wall and first end and second ends, a pattern within the wall defining a web structure configured for expansion from a collapsed position to an expanded position; anda membrane disposed about at least a portion of the tubular member, a plurality of pores being formed in the membrane, at least some of the pores having a maximum width of about 100 μm to reduce release of emboli larger than a predetermined size from the wall into a lumen upon expansion into the lumen of the tubular member from the collapsed position to the expanded position and having a minimum width to enable endothelial cell ingrowth, the pores having different sizes in different positions between the first and the second ends of the tubular member. 14. The covered endoprosthesis according to claim 13, wherein the membrane is formed by a weaving, knitting or braiding process. 15. The covered endoprosthesis according to claim 13, wherein the membrane includes a coating comprising a therapeutically beneficial agent. 16. An apparatus for stenting comprising: a stent having first and second ends and a lumen extending therebetween, the stent configured for expansion from a collapsed position to an expanded position; anda material disposed about a surface of the stent, the material having a plurality of pores formed along its length, at least some of the pores having a maximum width of about 100 μm to reduce release of emboli larger than a predetermined size and having a minimum width of about 30 μm to enable endothelial cell ingrowth. 17. The apparatus for stenting according to claim 16, wherein the plurality of pores are formed along the entire length of the stent. 18. The apparatus for stenting according to claim 16, wherein the material is disposed about an exterior surface of the stent. 19. The apparatus according to claim 16, further comprising a therapeutic coating disposed on the material.
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