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Production of nanocapsules and microcapsules by layer-wise polyelectrolyte self-assembly 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-009/14
  • A61K-009/16
  • A61K-009/48
출원번호 US-0502182 (2006-08-10)
등록번호 US-8092836 (2012-01-10)
우선권정보 DE-198 12 083 (1998-03-19); EP-98113181 (1998-07-15); DE-199 07 552 (1999-02-22)
발명자 / 주소
  • Donath, Edwin
  • Sukhorukov, Gleb B.
  • Lerche, Karl-Heinz
  • Voigt, Andreas
  • Bäumler, Hans
  • Caruso, Frank
  • Möhwald, Helmuth
출원인 / 주소
  • Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V.
대리인 / 주소
    Fanelli Haag PLLC
인용정보 피인용 횟수 : 6  인용 특허 : 34

초록

The invention relates to capsules coated with a polyelectrolyte shell and methods for the production thereof.

대표청구항

1. A capsule having a polyelectrolyte shell comprising alternating layers of cationic and anionic polyelectrolytes and wherein said capsule has a diameter of up to 10 μm and contains a lipid. 2. The capsule according to claim 1, having a diameter of ≦5 μm. 3. The capsule according to claim 1, prepar

이 특허에 인용된 특허 (34)

  1. Bader Hubert (Mainz DEX) Rppel Diether (Frankfurt am Main DEX) Walch Axel (Frankfurt am Main DEX) Magerstdt Michael (Liederbach DEX), Biologically degradable polyamide for depot preparations having controlled release of the active compound.
  2. Tsang Wen-Ghih (Lexington MA), Capsule loading technique.
  3. Foris ; Peter L. ; Brown ; Robert W. ; Phillips ; Jr. ; Paul S., Capsule manufacture.
  4. Foris Peter L. (Appleton WI) Brown Robert W. (Appleton WI) Phillips ; Jr. Paul S. (Appleton WI), Capsule manufacture.
  5. Chassot Laurent,CHX, Composite pigment.
  6. Epchtein Jacques S. (Avenida Alexandre Petta ; 953 Vila Resende 13400 Piracicaba ; Sao Paulo BRX), Continuous process for the fermentation of must to produce wine or ethanol.
  7. Sparks Randall T. (Gainesville GA) Geoghegan Edward J. (Athlone IEX), Controlled release powder and process for its preparation.
  8. Caruso, Frank; Trau, Dieter; Möhwald, Helmuth; Renneberg, Reinhard, Encapsulation of crystals via multilayer coatings.
  9. Tsang Wen-Ghih (Lexington MA) Shyr Ann W. (Newton Center MA), Encapsulation of materials.
  10. Frank Caruso DE; Rachel Anne Caruso DE; Edwin Donath DE; Helmuth Mohwald DE; Gleb Sukhorukov RU, Fabrication of multilayer-coated particles and hollow shells via electrostatic self-assembly of nanocomposite multilayers on decomposable colloidal templates.
  11. Cohen Smadar (Petach-Tickva MA ILX) Andrianov Alexander K. (Belmont MA) Wheatley Margaret (Media PA) Allcock Harry R. (State College PA) Langer Robert S. (Newton MA), Gas-filled polymeric microbubbles for ultrasound imaging.
  12. Wheatley Margaret A. ; Narayan Padma J., Hollow polymer microcapsules and method of producing the same.
  13. Cohen Smadar (12 Tfuzoth Israel Petach-Tickya ILX 49581) Bano Carmen (Juardia Civil 23 ; esc. 5 46020 Valencia PA ESX) Visscher Karyn B. (800-14 Stratford Dr. State College PA 16801) Chow Marie B. (5, Ionically cross-linked polymeric microcapsules.
  14. Whalen-Shaw Michael (7041 Zane Trail Rd. Circleville OH 43113), Layered composite pigments and method of making same.
  15. Jarvis ; Jr. Allan P. (Newburyport MA) Lim Franklin (Richmond VA), Method of culturing anchorage dependent cells.
  16. Curtis Ralston (Mountain View CA) Jain Rakesh (Gilroy CA) Creech David C. (Yuma AZ) Fitch William L. (Palo Alto CA), Microcapsules.
  17. Ferguson Gregory S. ; Kleinfeld Elaine R., Multilayered nanostructures comprising alternating organic and inorganic ionic layers.
  18. Kresse Mayk (Berlin DEX) Lawaczeck Rudiger (Berlin DEX) Pfefferer Detlef (Berlin DEX), Nanocrystalline magnetic iron oxide particles-method for preparation and use in medical diagnostics and therapy.
  19. Kenneth A. Larson ; William R. Campbell ; Douglas I. Hepler, Phospholipid-coated microcrystals for the sustained release of pharmacologically active compounds and methods of their manufacture and use.
  20. Haynes Duncan H. (4051 Barbarossa Ave. Miami FL 33133), Phospholipid-coated microcrystals: injectable formulations of water-insoluble drugs.
  21. Laguitton, Bruno, Polyanion/polycation multilayer film for DNA immobilization.
  22. Neu, Bjorn; Baumler, Hans; Donath, Edwin; Moya, Sergio; Sukhobukov, Gleb; Mohwald, Helmuth; Caruso, Frank, Polyelectrolyte coverings on biological templates.
  23. Dupuis Dominique,FRX ; LaBarre Dominique,FRX ; Mur Gilles,FRX, Polymer/CaCO.sub.3 composite core/sheath particulates and hollow CaCO.sub.3.
  24. Mulqueen Patrick J.,GBX ; Lubetkin Steven D.,GBX ; Smith Geoffrey W.,GBX ; Paterson Eric S., Preparation of aqueous emulsions.
  25. De Luca Patrick P. (Lexington KY) Rypacek Frantisek (Leckova CZX), Preparation of biodegradable microspheres useful as carriers for macromolecules.
  26. Follmann Heinrich (Minden DEX) Hoffmann Dietrich (Roedersheim-Gronau DEX) Sliwka Wolfgang (Weinheim DEX), Preparation of spherical, hard mono- or oligodisperse particles of melamine resin.
  27. Lim Franklin (Richmond VA), Preparation of substances with encapsulated cells.
  28. Somasundaran Ponisseril ; Chen Tsung-Yuan, Process for preparing nanocomposite particles.
  29. Liberti Paul A. (Hungingdon Valley PA) Piccoli Steven P. (Morrisville PA), Process of making resuspendable coated magnetic particles.
  30. Donath,Edwin; Sukhorukov,Gleb B.; Lerche,Karl Heinz; Voigt,Andreas; B채umler,Hans; Caruso,Frank; M철hwald,Helmuth, Production of nanocapsules and microcapsules by layer-wise polyelectrolyte self-assembly.
  31. Beug Hartmut (Vienna ATX) Birnstiel Max L. (Vienna ATX) Cotten Matthew (Vienna ATX) Wagner Ernst (Langenzersdorf ATX), Protein-polycation conjugates.
  32. Linton Howard R. (Wilmington DE), Silica particulate composition.
  33. Samain Daniel,FRX ; Delrieu Pascal,FRX ; Gibilaro Joelle,FRX ; Dirson Roselyne,FRX ; Cervilla Monique,FRX ; De Miguel Ignacio,FRX ; Ding Li,FRX ; Nguyen Frederique,FRX ; Soulet Nadine,FRX ; Soler Cor, Synthetic particulate vectors and preparation process.
  34. Bayerl Thomas,DEX ; Decher Gero,DEX ; Braunschweig Thomas,DEX, Template induced patterning of surfaces and their reversible stabilization using phase transitions of the patterned material.

이 특허를 인용한 특허 (6)

  1. Powell, Thomas J., Anti-malaria compositions and methods.
  2. Powell, Thomas J.; Boyd, James Gorham, Antigenic compositions and methods.
  3. Powell, Thomas J.; Boyd, James Gorham, Antigenic compositions and methods.
  4. Powell, Thomas J.; Boyd, James Gorham, Antigenic compositions and methods.
  5. Speaker, Tycho Joseph; Speaker, Sidra Lenore; Speaker, Talia Kalei, Microcapsules comprising a water-immiscible core and a wall comprising the salt of a lewis acid and a lewis base.
  6. Speaker, Tycho Joseph; Speaker, Sidra Lenore; Speaker, Talia Kalei, Products containing charged polymer complex microcapsules and method of use.
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