IPC분류정보
국가/구분 |
United States(US) Patent
등록
|
국제특허분류(IPC7판) |
|
출원번호 |
US-0021559
(2011-02-04)
|
등록번호 |
US-8105264
(2012-01-31)
|
발명자
/ 주소 |
- Noda, Wayne A.
- Jones, Mike L.
- Evans, Scott M.
- Walker, Blair D.
- Worchen, William J.
- Gobin, Yves Pierre
|
출원인 / 주소 |
|
대리인 / 주소 |
|
인용정보 |
피인용 횟수 :
18 인용 특허 :
13 |
초록
▼
A catheter is adapted to exchange heat with a body fluid, such as blood, flowing in a body conduit, such as a blood vessel. The catheter includes a shaft with a heat exchange region disposed at its distal end. This region may include hollow fibers which are adapted to receive a remotely cooled heat
A catheter is adapted to exchange heat with a body fluid, such as blood, flowing in a body conduit, such as a blood vessel. The catheter includes a shaft with a heat exchange region disposed at its distal end. This region may include hollow fibers which are adapted to receive a remotely cooled heat exchange fluid preferably flowing in a direction counter to that of the body fluid. The hollow fibers enhance the surface area of contact, as well as the mixing of both the heat exchange fluid and the body fluid. The catheter can be positioned to produce hypothermia in a selective area of the body or alternatively positioned to systemically cool the entire body system.
대표청구항
▼
1. Heat exchange catheter comprising: catheter body; andat least one heat exchange element distally associated with the catheter body and having either or both of: exterior structure that disrupts laminar flow of blood therealong, and interior structure that disrupts laminar flow of heat exchange fl
1. Heat exchange catheter comprising: catheter body; andat least one heat exchange element distally associated with the catheter body and having either or both of: exterior structure that disrupts laminar flow of blood therealong, and interior structure that disrupts laminar flow of heat exchange fluid therealong, heat exchange fluid flowing through the heat exchange element but not into a patient in which the catheter is disposed to exchange heat with a patient's body;wherein at least one heat exchange element is externally fluted in a spiral configuration along at least a segment thereof, wherein body fluid laterally outward of the heat exchange element cannot flow between the heat exchange element and a long axis defined by the spiral configuration of the heat exchange element. 2. The catheter of claim 1, comprising plural heat exchange elements axially arranged with respect to each other. 3. The catheter of claim 1, wherein the catheter is provided with distal metal structure. 4. The catheter of claim 1, comprising an anti-thrombogenic coating on at least a portion of the catheter. 5. The catheter of claim 1, wherein the heat exchange element externally fluted in a spiral configuration has exterior structure that disrupts laminar flow of blood therealong. 6. The catheter of claim 1, wherein at least one heat exchange element has interior structure that disrupts laminar flow of heat exchange fluid therealong. 7. The catheter of claim 5, wherein the heat exchange element externally fluted in a spiral configuration has interior structure that disrupts laminar flow of heat exchange fluid therealong. 8. Apparatus comprising: a catheter body having at least one heat exchange fluid lumen; andat least one heat exchange element communicating with the lumen such that heat exchange fluid is through the heat exchange element to exchange heat with blood of a patient when the heat exchange element is positioned in bloodstream of the patient, the heat exchange fluid not entering the bloodstream, wherein the heat exchange element(s) are configured to enhance heat exchange by being configured with at least one irregular surface next to which blood and/or heat exchange fluid flows;wherein a single heat exchange element is formed with plural spiral flutes. 9. The apparatus of claim 8, wherein the irregular surface is spiral-shaped. 10. The apparatus of claim 8, wherein the irregular surface is established by structure defining peaks and valleys to upset laminar flow of fluid. 11. The apparatus of claim 8, wherein the irregular surface is established by ridges. 12. The apparatus of claim 8, wherein tips of flutes on the heat exchange element define walls having a thickness greater than a thickness of other portions of the catheter. 13. The apparatus of claim 8, wherein first and second heat exchange elements are separated from each other by a flex region. 14. The apparatus of claim 8, wherein the body has a stiffness at a first location of the body that is different from a stiffness at a second location of the body. 15. The apparatus of claim 14, wherein the first location has a first diameter and the second location has a second diameter different from the first location. 16. The apparatus of claim 8, wherein body fluid laterally outward of the heat exchange element cannot flow between the heat exchange element and a long axis defined by the spiral flutes. 17. The apparatus of claim 8, comprising plural heat exchange elements axially arranged along the body such that the catheter can bend and flex when placed in a curved vasculature and is not as rigid, stiff and inflexible by comparison to a single heat exchange element catheter. 18. The apparatus of claim 8, comprising an anti-thrombogenic coating on at least a portion of the catheter. 19. The apparatus of claim 17, wherein the heat exchange elements extend axially along a surface of the body. 20. The apparatus of claim 8, comprising a hydrophilic or hydrophobic coating on at least a portion of the catheter. 21. The apparatus of claim 8, wherein a pressure gradient is established from a first end of the heat exchange element to a second end thereof. 22. Apparatus comprising: a catheter body having at least one heat exchange fluid lumen; andat least one heat exchange element communicating with the lumen such that heat exchange fluid is through the heat exchange element to exchange heat with blood of a patient when the heat exchange element is positioned in bloodstream of the patient, the heat exchange fluid not entering the bloodstream, wherein the heat exchange element(s) defines structure to upset laminar flow of fluid therealong;wherein at least one heat exchange element is externally fluted in a helical configuration along at least a segment thereof, wherein body fluid laterally outward of the heat exchange cannot pass to a long axis defined by the spiral configuration of the heat exchange element. 23. The apparatus of claim 22, wherein the structure includes at least one irregular surface next to which blood and/or heat exchange fluid flows. 24. The apparatus of claim 23, wherein the irregular surface is spiral-shaped. 25. The apparatus of claim 22, wherein the structure is established by peaks and valleys. 26. The apparatus of claim 22, wherein the structure is established by ridges. 27. The apparatus of claim 22, wherein a single heat exchange element is externally fluted in a spiral configuration along at least a segment thereof. 28. The apparatus of claim 22, wherein tips of flutes on the heat exchange element define walls having a thickness greater than a thickness of other portions of the catheter. 29. The apparatus of claim 22, comprising first and second heat exchange elements separated from each other by a flex region. 30. The apparatus of claim 22, wherein the body has a stiffness at a first location of the body that is different from a stiffness at a second location of the body. 31. The apparatus of claim 30, wherein the first location has a first diameter and the second location has a second diameter different from the first location. 32. The apparatus of claim 22, comprising plural heat exchange elements axially arranged along the body such that the catheter can bend and flex when placed in a curved vasculature and is not as rigid, stiff and inflexible by comparison to a single heat exchange element catheter. 33. The apparatus of claim 22, comprising an anti-thrombogenic coating on at least a portion of the catheter. 34. The apparatus of claim 22, comprising a hydrophilic or hydrophobic coating on at least a portion of the catheter. 35. The apparatus of claim 22, wherein a pressure gradient is established from a first end of the heat exchange element to a second end thereof.
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