초록 ▼

Needle-free hypodermic jet injection devices having an actuation system to effect an injection from a drug delivery system. The actuation system includes an injection force assembly adapted to transmit a driving force to the drug delivery system. The actuation system further includes a trigger assem

Needle-free hypodermic jet injection devices having an actuation system to effect an injection from a drug delivery system. The actuation system includes an injection force assembly adapted to transmit a driving force to the drug delivery system. The actuation system further includes a trigger assembly adapted to alter the actuation system between a plurality of configurations including a fired configuration in which the injection force assembly transmits a driving force to the drug delivery system. In some embodiments, the device has a recoil restriction system including a restriction member adapted to couple the recoil restriction system to the trigger assembly and a recoil member coupled to the injection force assembly and movable relative to the restriction member. The restriction member limits movement of the recoil member once the recoil member moves a predetermined distance relative to the restriction member.

대표청구항 ▼

1. A needle-free injection device comprising: a drug delivery system including a nozzle having a drug chamber and an outlet orifice, the drug delivery system adapted to expel a volume of liquid from the drug chamber through the outlet orifice;an actuation system including: an injection force assembl

1. A needle-free injection device comprising: a drug delivery system including a nozzle having a drug chamber and an outlet orifice, the drug delivery system adapted to expel a volume of liquid from the drug chamber through the outlet orifice;an actuation system including: an injection force assembly comprising a source of pressurized gas adapted to transmit a driving force to the drug delivery system, and a spring-driven hammer member adapted to engage the source of pressurized gas with the drug delivery system by urging the source of pressurized gas towards a pierce pin to release the pressurized gas;a trigger assembly adapted to operatively couple the actuation system with the drug delivery system, the trigger assembly including a retaining member adapted to limit activation of the injection force assembly; anda recoil restriction system adapted to limit movement of the injection force assembly and including a recoil member having a first end coupled to the hammer member and a second end adapted to engage with the retaining member. 2. The device of claim 1, wherein the recoil restriction system further includes a restriction member adapted to limit movement of the recoil member and comprising a beveled edge formed around an aperture in the retaining member through which the recoil member passes. 3. The device of claim 2, wherein the recoil member includes flanges adapted to engage with the beveled edge. 4. The device of claim 1, wherein the retaining member includes detents adapted to releasably couple with the hammer member. 5. The device of claim 1, wherein the trigger assembly further includes first and second housings adapted to move selectively relative to one another to alter the actuation system between a stored configuration in which the drug chamber is not in fluid communication with the outlet orifice, and a primed configuration in which the drug chamber is in fluid communication with the outlet orifice. 6. The device of claim 5, wherein the trigger assembly further includes a trigger sleeve adapted to limit movement of the first and second housings from the primed configuration to the stored configuration. 7. The device of claim 6, wherein the trigger sleeve includes protrusions adapted to limit relative movement between the first and second housings in a predetermined direction. 8. A needle-free injection device comprising: a drug delivery system including a nozzle having a drug chamber and an outlet orifice, the drug delivery system adapted to expel a volume of liquid from the drug chamber through the outlet orifice;an actuation system including: an injection force assembly adapted to transmit a driving force tothe drug delivery system; anda trigger assembly adapted to alter the actuation system between a plurality of configurations including a fired configuration in which the injection force assembly transmits a driving force to the drug delivery system, wherein the trigger assembly includes selectively engageable first and second interior housings adapted to couple the actuation system with the drug delivery system, and a trigger sleeve adapted to limit relative movement between the first and second housings; anda body configured to house the drug delivery system and the actuation system, the body including: an outer housing configured to receive the drug delivery system, anda back cover configured to rotatably couple with the outer housing, wherein rotation of the back cover and the trigger sleeve is coupled and axial movement between the back cover and the outer housing is restricted. 9. The device of claim 8, wherein the trigger sleeve includes protrusions extending into the body and configured to limit movement of the trigger sleeve relative to the body and channels configured to couple movement of the trigger sleeve with one of the first and second housings. 10. The device of claim 8, wherein the plurality of configurations further includes a stored configuration in which the drug chamber is not in fluid communication with the outlet orifice and a primed configuration in which the drug chamber is in fluid communication with the outlet orifice, and the trigger assembly includes a retaining member adapted to limit transmission of a driving force when the actuation system is in the stored and primed configurations. 11. The device of claim 10, wherein the retaining member includes detents adapted to releasably couple with the injection force assembly. 12. The device of claim 8, wherein the trigger assembly includes a trigger spring biased to restrict alteration of the actuation system to the fired configuration in response to an axial force less than a predetermined magnitude. 13. The device of claim 8, wherein the device further comprises a recoil restriction system including a recoil member coupled to the injection force assembly, the recoil restriction system adapted to limit movement of the injection force assembly when the actuation system is in the fired configuration.