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Heat-reduction methods and systems related to microfluidic devices

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • B01L-003/00
출원번호 US-0904432 (2010-10-14)
등록번호 US-8110158 (2012-02-07)
발명자 / 주소
  • Handique, Kalyan
출원인 / 주소
  • HandyLab, Inc.
대리인 / 주소
    Knobbe Martens Olson & Bear LLP
인용정보 피인용 횟수 : 43  인용 특허 : 332

초록

A system and method for preventing or reducing unwanted heat in a microfluidic of the device while generating heat in selected regions of the device. In one example, current is supplied to a heating element through electric leads, wherein the leads are designed so that the current density in the lea

대표청구항

1. An integrated microfluidic processing system comprising a microfluidic device, the device comprising: a microfluidic complex comprising at least one thermally actuated component, wherein at least one thermally actuated component is configured for moving fluid in the microfluidic device;a thermall

이 특허에 인용된 특허 (332)

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  180. Soane David S. (Piedmont CA) Soane Zoya M. (Piedmont CA), Method and device for moving molecules by the application of a plurality of electrical fields.
  181. Soane David S. ; Soane Zoya M., Method and device for moving molecules by the application of a plurality of electrical fields.
  182. Cherukuri Satyam C. (Cranbury NJ) Demers Robert R. (Cranbury NJ) Fan Zhong H. (Middlesex NJ) Levine Aaron W. (Lawrenceville NJ) McBride Sterling E. (Lawrence Township ; Mercer County NJ) Zanzucchi Pe, Method and system for inhibiting cross-contamination in fluids of combinatorial chemistry device.
  183. Cherukuri Satyam Choudary ; Demers Robert Richard ; Fan Zhong Hui Hugh ; Levine Aaron W. ; McBride Sterling Edward ; Zanzucchi Peter John, Method and system for inhibiting cross-contamination in fluids of combinatorial chemistry device.
  184. Bouma Stanley R. (Grayslake IL) Khalil Omar S. (Libertyville IL) Pabich Edward K. (Chicago IL), Method for detection of nucleic acid using total internal reflectance.
  185. Kaartinen Niilo (Vuolahti SF-21620 Kuusisto FIX), Method for producing a heatable and refrigerable element for a system handling small quantities of liquid, and an elemen.
  186. Benvegnu Dominic ; McCormick Randy M., Method for sample injection in microchannel device.
  187. David A. Boulton ; Carolyn I. Solewski, Method for sealing and venting a microplate assembly.
  188. Wilson Richard K. ; Mardis Elaine R. ; Panussis Dimitrios A., Method for transferring micro quantities of liquid samples to discrete locations.
  189. Miller William E. (Los Gatos CA), Method of late programming MOS devices.
  190. Anderson Rolfe C. ; Lipshutz Robert J. ; Rava Richard P. ; Fodor Stephen P. A., Method of manipulating a gas bubble in a microfluidic device.
  191. Mase Syunzo (Ama JPX) Soejima Shigeo (Nagoya JPX), Method of manufacturing an electrochemical device.
  192. McReynolds Richard J., Method of manufacturing microfluidic devices.
  193. Lau Hon-Peng P. (Hockessin DE), Method of performing affinity separation using immobilized flocculating agent on chromatographic support.
  194. Thatcher David R.,GBX ; Hitchcock Anthony,GBX ; Hanak Julian A.J.,GBX ; Varley Diane L.,GBX, Method of plasmid DNA production and purification.
  195. Thaler Barry Jay ; Quinn Robert Leon ; Braun Paul Leonard ; Zanzucchi Peter J. ; Burton Charlotte A. ; McBride Sterling E. ; Demers Robert R., Method of producing micro-electrical conduits.
  196. Vorpahl John, Method of separation employing magnetic particles and second medium.
  197. Zanzucchi Peter John (West Windsor Township ; Mercer County NJ) Cherukuri Satyam Choudary (Cranbury NJ) McBride Sterling Edward (Lawrence Township ; Mercer County NJ) Judd Amrit Kaur (Belmont CA), Method of synthesis of plurality of compounds in parallel using a partitioned solid support.
  198. Parce John Wallace ; Kopf-Sill Anne R., Methods and apparatus for in situ concentration and/or dilution of materials in microfluidic systems.
  199. Parce John Wallace ; Kopf-Sill Anne R., Methods and apparatus for in situ concentration and/or dilution of materials in microfluidic systems.
  200. Wilding Peter (Paoli PA) Kricka Larry J. (Berwyn PA) Zemel Jay N. (Jenkintown PA), Methods and apparatus for the detection of an analyte utilizing mesoscale flow systems.
  201. Wainright Ann K. ; Visser Irene ; Singh Sharat, Methods and compositions for conducting processes in microfluidic devices.
  202. Nikiforov Theo T. ; Jeong Sang, Methods and systems for enhanced fluid transport.
  203. Kopf-Sill Anne R., Methods and systems for monitoring and controlling fluid flow rates in microfluidic systems.
  204. Dubrow Robert S., Methods and systems for performing electrophoretic molecular separations.
  205. Heller Michael J. ; Tu Eugene, Methods for electronic synthesis of polymers.
  206. Heller Michael James ; O'Connell James Patrick ; Juncosa Robert David ; Sosnowski Ronald George ; Jackson Thomas Ratcliffe, Methods for hybridization analysis utilizing electrically controlled hybridization.
  207. Terasaki Paul I. (Los Angeles CA) Aoki Dennis (Los Angeles CA), Microdroplet test apparatus.
  208. Marc A. Unger ; Hou-Pu Chou ; Todd A. Thorsen ; Axel Scherer ; Stephen R. Quake, Microfabricated elastomeric valve and pump systems.
  209. Northrup M. Allen (Berkeley CA) White Richard M. (Berkeley CA), Microfabricated reactor.
  210. Northrup M. Allen (Berkeley CA) White Richard M. (Berkeley CA), Microfabricated reactor.
  211. Northrup M. Allen (Berkeley CA) White Richard M. (Berkeley CA), Microfabricated reactor.
  212. Webster, James Russell, Microfluidic actuator.
  213. Moles Donald R., Microfluidic analyzer module.
  214. Calvin Y. H. Chow ; Morten J. Jensen ; Colin B. Kennedy ; Michael M. Lacy ; Robert E. Nagle, Microfluidic controller and detector system with self-calibration.
  215. Michael Knapp ; John Wallace Parce ; Luc J. Bousse ; Anne R. Kopf-Sill, Microfluidic devices and methods for separation.
  216. Kennedy Colin B., Microfluidic devices and systems.
  217. Dubrow Robert S. ; Kennedy Colin B. ; Nagle Robert, Microfluidic devices and systems incorporating cover layers.
  218. Dubrow Robert S. ; Kennedy Colin B. ; Bousse Luc J., Microfluidic devices incorporating improved channel geometries.
  219. Dubrow Robert S. ; Kennedy Colin B. ; Bousse Luc J., Microfluidic devices incorporating improved channel geometries.
  220. Chow Andrea W. ; Kopf-Sill Anne R. ; Parce J. Wallace ; Sundberg Steven A., Microfluidic devices, systems and methods for performing integrated reactions and separations.
  221. Loewy Zvi ; Kumar Rajan, Microfluidic method for nucleic acid amplification.
  222. John Wallace Parce ; Anne R. Kopf-Sill ; Luc J. Bousse, Microfluidic systems.
  223. Michael Knapp ; John Wallace Parce ; Luc J. Bousse ; Anne R. Kopf-Sill, Microfluidic systems and methods of genotyping.
  224. Kayyem, Jon Faiz, Microfluidic systems in the electrochemical detection of target analytes.
  225. Kopf-Sill Anne R. ; Parce John Wallace, Microfluidic systems incorporating varied channel dimensions.
  226. Kopf-Sill Anne R. ; Parce John Wallace, Microfluidic systems incorporating varied channel dimensions.
  227. Cunanan Chris, Microplate scanning read head.
  228. Parce John Wallace, Micropump.
  229. Burns Mark A. ; Mastrangelo Carlos H. ; Sammarco Timothy S. ; Man Francis P. ; Webster James R. ; Johnson Brian N. ; Foerster Bradley ; Jones Darren, Microscale devices and reactions in microscale devices.
  230. Burns Mark A. ; Mastrangelo Carlos H. ; Sammarco Timothy S. ; Man Francis P. ; Webster James R. ; Johnson Brian N. ; Foerster Bradley ; Jones Darren ; Fields Yakeitha ; Kaiser Adam ; Burke David T., Microscale devices and reactions in microscale devices.
  231. Karger Barry L. ; Foret Frantisek ; Zavracky Paul M. ; McGruer E. Nicol ; Xue Qifeng ; Dunayevskiy Yuriy M., Microscale fluid handling system.
  232. Lang Volker,DEX, Microvalve.
  233. Mathies Richard A. ; Woolley Adam T., Miniature reaction chamber and devices incorporating same.
  234. Brown James F. (Clifton VA), Miniaturized biological assembly.
  235. Anderson Rolfe C. ; Lipshutz Robert J. ; Rava Richard P. ; Fodor Stephen P. A., Miniaturized genetic analysis systems and methods.
  236. Mileaf Daryl S. (Jessup MD) Rodgriguez ; II Noe E. (Severna Park MD), Mixing apparatus & method for an optical agglutination assay device.
  237. Heller Michael J. (Encinitas CA) Tu Eugene (San Diego CA) Butler William F. (Carlsbad CA), Molecular biological diagnostic systems including electrodes.
  238. Shieh Chan-Long (Paradise Valley AZ) Ackley Donald E. (Lambertville NJ) Maracas George N. (Phoenix AZ) Harvey ; III Thomas B. (Scottsdale AZ), Molecular detection apparatus and method using optical waveguide detection.
  239. Soane David S. (Piedmont CA), Mosaic microcolumns, slabs, and separation media for electrophoresis and chromatography.
  240. Handique Kalyan ; Gogoi Bishnu ; Burns Mark A. ; Mastrangelo Carlos H., Moving microdroplets.
  241. Handique, Kalyan; Gogoi, Bishnu; Burns, Mark A., Moving microdroplets.
  242. Tajima Hideji,JPX, Multi-vessel container for testing fluids.
  243. Tajima, Hideji, Multi-vessel container for testing fluids.
  244. Miller Bruce E., Multi-well reagent cartridge for treating a sample.
  245. Craig Stephen R., Multilayer integrated assembly having specialized intermediary substrate.
  246. Briscoe, Cynthia G.; Yu, Huinan; Grodzinski, Piotr; Marrero, Robert; Burdon, Jeremy W.; Huang, Rong-Fong, Multilayered microfluidic DNA analysis system and method.
  247. Ebersole Richard C. (Wilmington DE), Multilayered test device for detecting analytes in liquid test samples.
  248. Christian Clifford N. (Costa Mesa CA), Multiple assay card and system.
  249. Kennedy Colin B., Multiplexed microfluidic devices and systems.
  250. Lee Allan Christel ; Gregory T. A. Kovacs ; William A. McMillan ; M. Allen Northrup ; Kurt E. Petersen ; Farzad Pourahmadi, Non-planar microstructures for manipulation of fluid samples.
  251. Woudenberg,Timothy W.; Albin,Michael; Kowallis,Reid B.; Raysberg,Yefim; Ragusa,Robert P.; Winn Deen,Emily S., Nucleic acid analysis device.
  252. Komai Shigeru,JPX ; Daimon Katsuya,JPX ; Takarada Yutaka,JPX, Nucleic acid extraction apparatus.
  253. Chen Paul H.-D. (Boston MA) Findlay John B. (Rochester NY) Atwood Susan M. (Newark NY) Bergmeyer Lynn (Rochester NY), Nucleic acid material amplification and detection without washing.
  254. Haj-Ahmad Yousef,CAX, Nucleic acid purification and process.
  255. Kumar Rajan, Padlock probe detection.
  256. Southgate Peter David ; Andrevski Zygmunt Marian ; Roach William Ronald ; Zanzucchi Peter John, Parallel reaction cassette and associated devices.
  257. Kano Tokio (Akishima JPX) Tamagawa Akira (Hino JPX), Particle agglutination analyzing plate.
  258. Olander, Morten Aae; Lihme, Allan Otto Fog; Hobley, Timothy John; Simon, Marcos; Theodossiou, Irini; Thomas, Owen Robert Tyrynis, Particulate material for purification of bio-macromolecules.
  259. Zanzucchi Peter J. (Lawrenceville NJ) Cherukuri Satyam C. (Cranbury NJ) McBride Sterling E. (Lawrenceville NJ), Partitioned microelectronic and fluidic device array for clinical diagnostics and chemical synthesis.
  260. Zanzucchi Peter J. (West Windsor Township NJ) Cherukuri Satyam C. (Cranbury NJ) McBride Sterling E. (Lawrence Township NJ) Judd Amrit K. (Belmont CA), Partitioned microelectronic device array.
  261. Zanzucchi Peter John ; Cherukuri Satyam Choudary ; McBride Sterling Edward, Partitioned microelectronic device array.
  262. Zanzucchi Peter John ; Cherukuri Satyam Choudary ; McBride Sterling Edward ; Judd Amrit Kaur, Partitioned microelectronic device array.
  263. Ball Melville D. (Kingston CAX) Coady Laurie A. (Stockholm SEX) Kuenzi Werner H. (Hirzel CHX) Jones Robert G. (Kingston CAX), Peelable laminated structures and process for production thereof.
  264. Wiedenmann Hans-Martin (Stuttgart DEX) Schneider Gerhard (Schwieberdingen DEX) Bayha Kurt (Oberriexingen DEX), Planar polarographic probe for determining the l 상세보기
  • Schneider Gerhard (Vaihingen DEX) Bayha Kurt (Oberriexingen DEX) Renz Hans-Joerg (Leinfelden-Echterdingen DEX), Planar polarographic sensor for determining the lambda value of gas mixtures.
  • Schneider Gerhard (Vaihingen DEX) Westphal Frank (Stegaurach DEX) Schuele Margret (Markgrningen DEX), Planar sensor element having a solid electrolyte substrate.
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  • Willis John P., Point-of-care analyzer module.
  • Arnold ; Jr. Lyle J. (San Diego CA) Nelson Norman C. (San Diego CA) Reynolds Mark A. (La Jolla CA) Waldrop ; III Alexander A. (San Diego CA), Polycationic supports and nucleic acid purification separation and hybridization.
  • Schiff Robert (Caldwell NJ) Lehnus Gary (Blairestown NJ) Wasserman Charles J. (Muskego WI) Garlock Henrietta M. (Oconomowoc WI), Polymer coated solid matrices and use in immunoassays.
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  • Mullis Kary B. (Kensington CA), Process for amplifying nucleic acid sequences.
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  • Rauf Ijaz (Kingston CAX), Process for engineering coherent twin and coincident site lattice grain boundaries in polycrystalline materials.
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  • LaBarbera Angelo M. (Honeoye NY) Salotto Daniel P. (Rochester NY), Processor for nucleic acid detection.
  • Fan Eugene (La Jolla CA) Huang Ching (Chula Vista CA) Wang Dou-Mei (Encinitas CA) Wilson Gregg L. (San Diego CA), Reaction unit for use in analyzing biological fluids.
  • Fan Eugene (La Jolla CA) Huang Ching (Chula Vista CA) Wang Dou-Mei (Encinitas CA) Wilson Gregg L. (San Diego CA), Reaction unit for use in analyzing biological fluids.
  • Hillman Robert S. (Cupertino CA), Reagent cartridge for blood analysis.
  • Miller Bruce E., Reagent cartridge for treating a sample.
  • Taylor Richard F. (W. Boxford) Marenchic Ingrid G. (Walpole) Cook Edward J. (South Hamilton MA), Receptor-based biosensors.
  • Werley Barry L. (Allentown PA) Snyder Richard H. (Macungie PA) McQuillen Joseph E. (Macungie PA) Miller Keith A. (Allentown PA), Safety pressure regulator.
  • Dickey Gilbert C. (23185 Woodville Rd. Genoa OH 43430), Safety release pipe cap.
  • Adamski ; Henry S., Sample cup tray for chemical analysis of biological fluids.
  • Bigler William E. (Elkhart IN) Cherepak Michael S. (Elkhart IN) Collister Kenneth D. (Elkhart IN) Postma Cynthia S. (Elkhart IN), Sample processor.
  • Gianino F. Thomas (Bradford MA), Sample tube holder.
  • Marino Kenneth J., Sample tube holder.
  • Boyd Robert, Sample tube rack.
  • Cohen Beri ; DeYoung Thomas, Sample tube rack.
  • Dumitrescu Nicolae ; Makarchuk Irena, Sample tube rack.
  • Dumitrescu Nicolae ; Makarchuk Irena, Sample tube rack.
  • Dumitrescu Nicolae ; Makarchuk Irena, Sample tube rack.
  • Baker Richard W. (Anoka MN) Funk Roger L. (Cedar MN), Self-calibrating single-use sensing device for clinical chemistry and method of use.
  • Charlton Steven C. (Osceola IN) Rebec Mihailo V. (Bristol IN) Ruetten Catherine (Granger IN), Self-metering fluid analysis device.
  • Charlton Steven C. (Osceola IN) Rebec Mihailo V. (Bristol IN) Ruetten Catherine (Granger IN), Self-metering fluid analysis device.
  • Baker Christopher J. S. (Richmond GB2) Whalley Peter D. (Slough GB2), Sensor arrangements.
  • Hooper Herbert H. (Belmont CA) Pacetti Stephen (Sunnyvale CA) Soane David S. (Piedmont CA) Bae Young C. (Seoul KRX), Separation media for electrophoresis.
  • Northrup M. Allen (Berkeley CA) Mariella ; Jr. Raymond P. (Danville CA) Carrano Anthony V. (Livermore CA) Balch Joseph W. (Livermore CA), Silicon-based sleeve devices for chemical reactions.
  • Whitmore Elaine (Arlington TX), Single use system for preparation of autologous plasma.
  • Legg Stephen P. (Southampton TX GB2) Schrottke Gustav (Austin TX), Soldering method.
  • Van Ness Jeffrey (Bothell WA) Petrie Charles R. (Woodinville WA) Tabone John C. (Bothell WA) Vermeulen Nicolaas M.J. (Woodinville WA) Reed Michael W. (Seattle WA), Solid supports for nucleic acid hybridization assays.
  • Barrett Ronald W. (Sunnyvale CA) Pirrung Michael C. (Durham NC) Stryer Lubert (Stanford CA) Holmes Christopher P. (Sunnyvale CA) Sundberg Steven A. (San Francisco CA), Spatially-addressable immobilization of anti-ligands on surfaces.
  • Perlman Daniel (Arlington MA), Sterile transfer system.
  • Yamanishi Eriko,JPX ; Miyazaki Shoji,JPX ; Fujiwara Masaki,JPX, Strip for blood test.
  • Amigo M. Goretty Alonso, Surface modified electrophoretic chambers.
  • Amigo M. Goretty Alonso ; McCormick Randy M., Surface modified electrophoretic chambers.
  • Berndt Klaus W. (Stewartstown PA), System for detecting bacterial growth in a plurality of culture vials.
  • Papen Roeland F. ; Pelc Richard E. ; Chibucos Nicholas S. ; Meyer Wilhelm,DEX, System for dispensing microvolume quantities of liquids.
  • Daniel Y. M. Chu ; Donald L. Rising ; Jeff Ceremony ; Cliff Baldwin, Temperature control for multi-vessel reaction apparatus.
  • Rando Joseph F. (Los Altos Hills CA) Fishman Ilya M. (Fremont CA), Temperature operated gas valve.
  • Gavin Michael ; Mawhirt James A. ; Allen Donald W., Test apparatus and method for testing cuvette accommodated samples.
  • McMenamy, Jim; Lin, James Feng, Test platform.
  • Lapeus David J. ; Ballash Michael, Test tube sample rack.
  • Lapeus David J. ; Ballash Michael, Test tube sample rack.
  • Thomas Michael D. (Arab AL), Testing tray.
  • Burns Mark A. ; Johnson Brian N. ; Chen Michael,SGX, Thermal microvalves in a fluid flow method.
  • Sassi Alexander P. (Berkeley CA) Lin Shi (Fremont CA) Alonso-Amigo M. Goretty (Santa Clara CA) Hooper Herbert H. (Belmont CA), Thermoreversible hydrogels comprising linear copolymers and their use in electrophoresis.
  • Sassi Alexander P. ; Lin Shi ; Alonso-Amigo M. Goretty ; Hooper Herbert H., Thermoreversible hydrogels comprising linear copolymers and their use in electrophoresis.
  • Lovborg Uffe (Koge DKX), Tube for the immunological adsorption analysis.
  • Hooper Herbert H. ; Sassi Alexander P. ; Soane David S. ; Bae Young,KRX, Un-crosslinked polymeric media for electrophoresis.
  • Guruswamy Vinodhini (Bethesda MD) Elliott Donald A. (Bethesda MD), Universal sensor cartridge for use with a universal analyzer for sensing components in a multicomponent fluid.
  • Kremer Paul (Walferdange LUX), Valve for a gas cylinder.
  • Brody James P., Valveless liquid microswitch.
  • Costello Walter H. (Wenonah NJ), Valveless shut-off and transfer device.
  • Chow Calvin Y. H. ; Parce J. Wallace, Variable control of electroosmotic and/or electrophoretic forces within a fluid-containing structure via electrical forc.
  • Chow Calvin Y. H. ; Parce J. Wallace, Variable control of electroosmotic and/or electrophoretic forces within a fluid-containing structure via electrical forc.
  • Swann Wayne E. (Columbia MD), Vermiculite as a carrier support for immobilized biological materials.
  • Buhler Jurg (Rothenburg CHX) Muller Siegfried (Meierskappel CHX), Vessel holder.
  • Mathis Scott E. ; Weber David P., Vial carrier.
  • Pelley ; III Perry H. ; Taft Robert C., Voltage regulator for regulating an output voltage from a charge pump and method therefor.
  • Culp Gordon W. (Van Nuys CA), Walking expansion actuator.
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    15. Handique, Kalyan; Ganesan, Karthik; Brahmasandra, Sundaresh N., Methods and systems for control of microfluidic devices.
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    19. Williams, Jeffrey; Brahmasandra, Sundaresh, Microfluidic cartridge for processing and detecting nucleic acids.
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