A variable hydraulic resistor for use with implantable pumps is disclosed. The variable hydraulic resistor according to the present invention is particularly useful in varying the flow rate of a medication fluid from an otherwise constant flow implantable pump. An implantable pump is also disclosed,
A variable hydraulic resistor for use with implantable pumps is disclosed. The variable hydraulic resistor according to the present invention is particularly useful in varying the flow rate of a medication fluid from an otherwise constant flow implantable pump. An implantable pump is also disclosed, which does not require a complicated clinching system or the like, and which may include an undulating membrane and chamber design to reduce the height of the pump.
대표청구항▼
1. An implantable device for dispensing an active substance to a patient comprising: a housing defining: a chamber;an outlet for delivering said active substance to a target site within said patient, said outlet in fluid communication with the chamber;a capillary in fluid communication between said
1. An implantable device for dispensing an active substance to a patient comprising: a housing defining: a chamber;an outlet for delivering said active substance to a target site within said patient, said outlet in fluid communication with the chamber;a capillary in fluid communication between said chamber and said outlet;a polymer filament located in the capillary for dynamically varying a flow rate of said active substance between said chamber and said outlet, said filament having a first state with a first length and a first cross sectional dimension and a second state with a second length and a second cross sectional dimension, the first length being less than the second length and the first cross sectional dimension being greater than the second cross sectional dimension, wherein the second cross sectional dimension of the filament allows for a greater flow rate than the first cross sectional dimension; andmeans for elongating the filament from the first state to the second state. 2. The implantable device according to claim 1, wherein the chamber includes an active substance chamber in fluid communication with said outlet and a propellant chamber, the active substance and propellant chambers being separated by a flexible membrane. 3. The implantable device according to claim 2, wherein the propellant chamber contains a propellant capable of expanding isobarically, the propellant cooperating with the flexible membrane to reduce a volume of the active substance chamber upon expansion of the propellant. 4. The implantable device according to claim 2, further comprising an opening in said housing in fluid communication with the active substance chamber, and a first septum sealing the opening. 5. The implantable device according to claim 4, further comprising an annular opening in said housing communicating with said outlet, and a second septum sealing the annular opening. 6. The implantable device according to claim 1, wherein the filament is located centrally within said capillary. 7. The implantable device according to claim 1, wherein the filament is located eccentrically within said capillary. 8. The implantable device according to claim 7, wherein the filament has a uniform cross section along its length. 9. The implantable device according to claim 8, wherein the filament has a substantially circular cross section. 10. The implantable device according to claim 7, wherein the filament has a non-uniform cross section along its length. 11. The implantable device according to claim 1, wherein said means for elongating the filament includes at least two magnetic elements. 12. The implantable device according to claim 1, wherein said means for elongating the filament includes an axle. 13. The implantable device according to claim 1, further comprising means for controlling said means for elongating the filament. 14. The implantable device according to claim 13, wherein the means for controlling are wireless. 15. An implantable device for dispensing an active substance to a patient comprising: a housing defining: a chamber;an outlet for delivering said active substance to a target site within said patient, said outlet in fluid communication with the chamber;a capillary in fluid communication between said chamber and said outlet, said capillary having an inner surface;a flow control element received within said capillary, said element having a first state with a first length and an outer surface opposing said inner surface of said capillary defining therebetween a first passageway for a flow of said active substance therethrough, said element having a second state with a second length and said outer surface and said inner surface defining therebetween a second passageway for the flow of said active substance therethrough, the first length being less than the second length and the first passageway being less in size than the second passageway; andmeans for elongating the flow control element from the first state to the second state. 16. The implantable device according to claim 15, wherein movement of said outer surface of said element alters the shape of said passageway. 17. The implantable device according to claim 15, wherein said flow control element is an elongated polymer filament having a cross sectional dimension, the filament capable of being elongated to reduce the cross sectional dimension. 18. The implantable device according to claim 17, wherein the filament is located centrally within said capillary. 19. The implantable device according to claim 17, wherein the filament is located eccentrically within said capillary. 20. The implantable device according to claim 17, wherein the filament has a uniform cross section along its length. 21. The implantable device according to claim 20, wherein the filament has a substantially circular cross section. 22. The implantable device according to claim 17, wherein the filament has a non-uniform cross section along its length. 23. The implantable device according to claim 15, wherein said means for elongating the filament includes at least two magnetic elements. 24. The implantable device according to claim 15, wherein said means for elongating the filament includes an axle. 25. The implantable device according to claim 15, further comprising means for controlling the movement of said flow control element. 26. The implantable device according to claim 25, wherein the means for controlling are wireless. 27. A method of varying a flow rate of an active substance being dispensed to a patient comprising: providing an implantable device including a capillary having an inner surface, a flow control element received within said capillary, said flow control element having an outer surface opposing said inner surface of said capillary defining therebetween a passageway for flow of said active substance therethrough to a target site within a patient, and means for elongating said flow control element from a first state to a second state;implanting said implantable device in said patient; andelongating said flow control element from the first state to the second state to alter a cross sectional dimension of the passageway to alter the flow of said active substance therethrough. 28. The method according to claim 27, wherein elongating said flow control element from the first state to the second state increases the cross sectional dimension of said passageway. 29. The method according to claim 27, wherein elongating said flow control element from the first state to the second state alters the shape of said passageway.
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