System and method for conducting hemodialysis and hemofiltration
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
B01D-061/30
B01D-061/32
B01D-061/28
출원번호
US-0324924
(2008-11-28)
등록번호
US-8114288
(2012-02-14)
발명자
/ 주소
Robinson, Thomas Patrick
Clemens, Charles E.
Mishelevich, David Jacob
Braig, James Roswell
Fulkerson, Barry Neil
Ghidoli, Daniele
Joseph, Russell Thomas
출원인 / 주소
Fresenlus Medical Care Holdings, Inc.
대리인 / 주소
Novel IP
인용정보
피인용 횟수 :
23인용 특허 :
130
초록▼
An extracorporeal blood processing system comprises a plastic molded compact manifold that supports a plurality of molded blood and dialysate fluidic pathways along with a plurality of relevant sensors, valves and pumps. A disposable dialyzer is connected to the molded manifold to complete the blood
An extracorporeal blood processing system comprises a plastic molded compact manifold that supports a plurality of molded blood and dialysate fluidic pathways along with a plurality of relevant sensors, valves and pumps. A disposable dialyzer is connected to the molded manifold to complete the blood circuit of the system. The compact manifold is also disposable in one embodiment and can be detachably installed in the dialysis machine. Two-way valves in the manifold are used to direct the dialysate flow to the dialyzer in hemodialysis mode of operation and to bypass the dialyzer to direct the flow of infusion grade dialysate directly to the patient in hemofiltration mode of operation.
대표청구항▼
1. A manifold for a blood purification system, the manifold comprising: a first fluid conducting segment wherein said first fluid conducting segment comprises a rigid plastic substrate, wherein said first fluid conducting segment comprises a first portion of a first flow path, and wherein said first
1. A manifold for a blood purification system, the manifold comprising: a first fluid conducting segment wherein said first fluid conducting segment comprises a rigid plastic substrate, wherein said first fluid conducting segment comprises a first portion of a first flow path, and wherein said first fluid conducting segment comprises a first port located at an edge of the first fluid conducting segment;a second fluid conducting segment parallel to said first fluid conducting segment wherein said second fluid conducting segment comprises a rigid plastic substrate, wherein said second fluid conducting segment comprises a second portion of the first flow path, wherein said second fluid conducting segment comprises a second port located at an edge of the second fluid conducting segment, and wherein said first and second ports are positioned opposite each other;a connecting fluid conducting segment that is perpendicular to, and separates, the first and second fluid conducting segments; anda flexible tube having a first end and a second end, wherein said first end of the tube is attached to said first port, wherein said second end of the tube is attached to said second port, wherein said tube serves to connect said first portion of the first flow path to said second portion of the first flow path, and wherein the connecting fluid conducting segment is a parallel to said flexible tube. 2. The manifold of claim 1, wherein said manifold is disposable. 3. The manifold of claim 1, wherein each of said first fluid conducting segment, second fluid conducting segment, and connecting fluid conducting segments comprise external edges that define a boundary bounding a space. 4. The manifold of claim 1 further comprising at least one valve component fixedly attached to at least one of said first fluid conducting segment, second fluid conducting segment, or connecting fluid conducting segments for directing fluid flow through the first flow path, a second flow path, or a third flow path. 5. The manifold of claim 1 further comprising at least one sensor component fixedly attached to at least one of said first fluid conducting segment, second fluid conducting segment, or connecting fluid conducting segments for measuring a fluid characteristic in at least one of the first flow path, a second flow path, or a third flow path. 6. The manifold of claim 5, wherein said fluid characteristic is at least one of temperature or pressure. 7. The manifold of claim 4, wherein activation of said valve component directs fluid flow through one of two separate fluid paths. 8. The manifold of claim 7, wherein said activation of the valve component is dependent upon a mode of operation of the blood purification system. 9. The manifold of claim 8, wherein said mode of operation is selected from the class comprising hemodialysis and hemofiltration. 10. A dialysis machine comprising a manifold as claimed in claim 1, further comprising: a door with a pressure plate positioned on an interior face of the door;a housing with a panel wherein said housing and panel define a recessed region configured to receive said interior face of said door; andan alignment mechanism fixedly attached to said panel, wherein said alignment mechanism detachably receives the manifold on said panel and positions said manifold against said pressure plate when the door is placed in said recessed region. 11. The dialysis machine of claim 10 wherein said alignment mechanism is at least one of contoured guides, pins, or latch. 12. The manifold of claim 1 wherein the first fluid conducting segment comprises a first portion of a second flow path and a third port located at an edge of the first fluid conducting segment. 13. The manifold of claim 12 wherein the second fluid conducting segment comprises a second portion of a second flow path and a fourth port located at an edge of the second fluid conducting segment, wherein said third and fourth ports are parallel to the connecting fluid conducting segment and are positioned opposite each other. 14. The manifold of claim 13 further comprising a second flexible tube having a first end and a second end, wherein said first end of the second tube is attached to said third port, wherein said second end of the second tube is attached to said fourth port, and wherein said second tube serves to connect said first portion of the second flow path to said second portion of the second flow path. 15. The manifold of claim 14 wherein the first fluid conducting segment comprises a first portion of a third flow path and a fifth port located at an edge of the first fluid conducting segment. 16. The manifold of claim 15 wherein the second fluid conducting segment comprises a second portion of a third flow path and a sixth port located at an edge of the second fluid conducting segment, wherein said fifth and sixth ports are parallel to the connecting fluid conducting segment and are positioned opposite each other. 17. The manifold of claim 16 further comprising a third flexible tube having a first end and a second end, wherein said first end of the third tube is attached to said fifth port, wherein said second end of the third tube is attached to said sixth port, and wherein said third tube serves to connect said first portion of the third flow path to said second portion of the third flow path. 18. The manifold of claim 17 wherein the first fluid conducting segment comprises a first portion of a fourth flow path and a seventh port located at an edge of the first fluid conducting segment. 19. The manifold of claim 18 wherein the second fluid conducting segment comprises a second portion of a fourth flow path and a eighth port located at an edge of the second fluid conducting segment, wherein said seventh and eighth ports are parallel to the connecting fluid conducting segment and are positioned opposite each other. 20. The manifold of claim 19 further comprising a fourth flexible tube having a first end and a second end, wherein said first end of the fourth tube is attached to said seventh port, wherein said second end of the fourth tube is attached to said eighth port, and wherein said fourth tube serves to connect said first portion of the fourth flow path to said second portion of the fourth flow path. 21. The manifold of claim 20 wherein each of said first, second, third, and fourth flow paths are isolated from each other.
연구과제 타임라인
LOADING...
LOADING...
LOADING...
LOADING...
LOADING...
이 특허에 인용된 특허 (130)
Fumiyama Hideo, Active blood filter and method for active blood filtration.
Heilmann Klaus (St. Wendel DEX) Mathieu Bernd (Spiesen-Elversberg DEX) Rink Michael (St. Ingbert-Hassel DEX) Weber Wolfram (Spiesen-Elversberg DEX), Apparatus for sterilizing a medical unit.
Ishihara Toshikazu (Yatagawa Park House C ; 10-7 ; Daiko-cho Aichi JPX) Kitano Tomoyuki (Yatagawa Park House C ; 10-7 ; Daiko-cho Aichi JPX) Maeda Kenji (Yatagawa Park House C ; 10-7 ; Daiko-cho Higa, Blood purification apparatus.
Burbank, Jeffrey H.; Brugger, James M.; Treu, Dennis M.; Finch, Jr., C. David, Blood treatment systems and methods that maintain sterile extracorporeal processing conditions.
Ash Stephen R. (Lafayette IN) Janle-Swain Elsa M. (West Lafayette IN), Capillary filtration and collection device for long-term monitoring of blood constituents.
Ash Stephen R. (Lafayette IN) Janle-Swain Elsa M. (West Lafayette IN), Capillary filtration and collection method for long-term monitoring of blood constituents.
Koerdt, Franz-Wilhelm; Kaiser, Peter; Hulsmann, Hans Georg, Device and method for carrying out a contactless measurement of the conductivity of a liquid situated in a flow channel.
Wamsiedler Ralf (Oberursel DEX) Wojke Ralf (Frankfurt DEX) Pieper Walter (Florstadt DEX) Christmann-Braun Horst (Kelkheim DEX), Diaphragm gage for measuring the pressure of a fluid.
Burbank, Jeffrey H.; Brugger, James M; Treu, Dennis M., Extracorporeal circuits for performing hemofiltration employing pressure sensing without an air interface.
Treu Dennis M. ; Burbank Jeffrey H. ; Brugger James M., Flow-through peritoneal dialysis systems and methods with on-line dialysis solution regeneration.
Burbank, Jeffrey H.; Brugger, James M.; Treu, Dennis M., Fluid processing systems and methods using extracorporeal fluid flow panels oriented within a cartridge.
Burbank, Jeffrey H.; Brugger, James M.; Treu, Dennis M., Fluid processing systems and methods using extracorporeal fluid flow panels oriented within a cartridge.
Yuli Kitaevich ; Nat Hemasilpin ; J. Gabriel Marchevsky ; John J. Bissler ; George Benzing, III ; Paul T. McEnery, Hemofiltration system and method based on monitored patient parameters.
Sekikawa Nobuyoshi (Asaka) Katsuyama Harumi (Asaka) Kondo Asaji (Asaka JPX), Integral multilayer analytical element for analysis of ammonia-forming substrate.
Ash Stephen R. (Lafayette IN) Janle Elsa M. (West Lafayette IN), Interstitial filtration and collection device and method for long-term monitoring of physiological constituents of the b.
Munis, James Robert; Lozada, Leonardo Jose; Zura, Andrew Michael, Method and apparatus for controlling blood volume and hydration and for indicating resuscitation status of a patient using peripheral venous pressure as a hemodynamic parameter.
Ash Stephen R. (Lafayette IN) Echard Terrance G. (West Lafayette IN), Method and apparatus for determining a rate of flow of blood for an extracorporeal blood therapy instrument.
Khuri Raja N. (122 Longmeadow Rd. Greenville NC 27858) Nakhoul Nazih L. (Greenville NC), Method for determining adequacy of dialysis based on urea concentration.
Brugger, James M.; Burbank, Jeffrey H.; Treu, Dennis M., Method for performing renal replacement therapy including producing sterile replacement fluid in a renal replacement therapy unit.
Deniega Jose C. (Lake Forest CA) Matsumoto Tsuyoshi (Tokyo JPX), Organizer frame for holding an array of flexible tubing in alignment with one or more peristaltic pump rotors.
Polaschegg Hans-Dietrich (Oberursel DEX), Process for determining the operability of the structural components in the dialysis section of a dialyzer of a hemodial.
Sherman John D. ; Bem David S. ; Lewis Gregory J., Process for removing toxins from bodily fluids using zirconium or titanium microporous compositions.
Handt Alan E. (705 Pineview Zionsville IN 46077) Ash Stephen R. (2500 N. 400 East Lafayette IN 47905), Short-tubing set gravity powered peritoneal cycler.
Sullivan,Thomas A.; Carr,David J.; Ash,Stephen R., Sorbent reactor for extracorporeal blood treatment systems, peritoneal dialysis systems, and other body fluid treatment systems.
Keeling Norman G. (McMurray PA) Ash Stephen R. (Lafayette IN) Truitt Robert B. (Lafayette IN) Guzman Joseph A. (Atlanta GA), Specialized perfusion protocol for whole-body hyperthermia.
Burbank, Jeffrey H.; Brugger, James M.; Treu, Dennis M.; Finch, Jr., C. David; Fulkerson, Barry N.; White, Steven A., Systems and methods for performing blood processing and/or fluid exchange procedures.
Robinson, Thomas Patrick; Clemens, Charles E.; Mishelevich, David Jacob; Braig, James Roswell; Fulkerson, Barry Neil; Ghidoli, Daniele; Joseph, Russell Thomas, Disposable apparatus and kit for conducting dialysis.
Robinson, Thomas Patrick; Clemens, Charles E.; Mishelevich, David Jacob; Braig, James Roswell; Fulkerson, Barry Neil; Ghidoli, Daniele; Joseph, Russell Thomas, Disposable apparatus and kit for conducting dialysis.
Robinson, Thomas Patrick; Clemens, Charles E.; Mishelevich, David Jacob; Braig, James Roswell; Fulkerson, Barry Neil; Ghidoli, Daniele; Joseph, Russell Thomas, Disposable apparatus and kit for conducting dialysis.
Fulkerson, Barry Neil; Fazio, Joe; Huang, Alec; Kelly, Brian Thomas; Nolan, Tam; Smith, Mark, Load suspension and weighing system for a dialysis machine reservoir.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.