최소 단어 이상 선택하여야 합니다.
최대 10 단어까지만 선택 가능합니다.
다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
NTIS 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
DataON 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
Edison 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
Kafe 바로가기국가/구분 | United States(US) Patent 등록 |
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국제특허분류(IPC7판) |
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출원번호 | US-0929945 (2007-10-30) |
등록번호 | US-8117734 (2012-02-21) |
발명자 / 주소 |
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출원인 / 주소 |
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대리인 / 주소 |
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인용정보 | 피인용 횟수 : 0 인용 특허 : 320 |
A process for the manufacture of small sensors with reproducible surfaces, including electrochemical sensors. One process includes forming channels in the surface of a substrate and disposing a conductive material in the channels to form an electrode. The conductive material can also be formed on th
A process for the manufacture of small sensors with reproducible surfaces, including electrochemical sensors. One process includes forming channels in the surface of a substrate and disposing a conductive material in the channels to form an electrode. The conductive material can also be formed on the substrate by other impact and non-impact methods. In a preferred embodiment, the method includes cutting the substrate to form a sensor having a connector portion and a transcutaneous portion, the two portions having edges that define one continuous straight line.
1. A method of manufacturing a sensor for the in vitro determination of the presence and/or level of glucose in a sample, the method comprising: disposing a conductive material on a substrate to provide one or more traces, at least one trace having a width of about 25 microns to 250 microns; andform
1. A method of manufacturing a sensor for the in vitro determination of the presence and/or level of glucose in a sample, the method comprising: disposing a conductive material on a substrate to provide one or more traces, at least one trace having a width of about 25 microns to 250 microns; andforming a sample chamber in the substrate so that the sensor can determine the presence and/or level of glucose in a volume of sample of about 1 microliter or less in the sample chamber. 2. The method of claim 1 wherein the volume of sample includes blood. 3. The method of claim 1 wherein the conductive material includes one or more of gold, palladium, carbon or conducting polymer. 4. The method of claim 1 wherein the one or more traces are formed using laser. 5. The method of claim 1 including two or more conductive traces. 6. The method of claim 5 wherein the two or more conductive traces are separated by a distance of approximately 150 microns or less. 7. The method of claim 1 wherein the one or more conductive traces includes one or more of a working electrode, a counter electrode or a reference electrode. 8. The method of claim 7 wherein at least a portion of the working electrode is in fluid contact with the volume of sample in the sample chamber. 9. The method of claim 8 wherein the at least the portion of the working electrode is in the sample chamber. 10. The method of claim 1 including a sensing layer in contact with the one or more conductive traces. 11. The method of claim 10 wherein the one or more conductive traces in contact with the sensing layer includes a working electrode. 12. A method of manufacturing a sensor for the in vitro determination of the presence and/or level of glucose in a sample, the method comprising: providing a substrate;disposing a conductive material on the substrate to provide one or more traces, at least one trace having a width of about 25 microns to 250 microns; andforming a sample chamber in the substrate to a volume of sample of about 1 microliter or less, the one or more traces configured to be in fluid contact with the volume of sample received in the formed sample chamber to determine the level of glucose in the volume of sample. 13. The method of claim 12 wherein the conductive material is disposed on the substrate using laser. 14. The method of claim 12 wherein the conductive material includes carbon ink. 15. The method of claim 12 wherein a density of the one or more conductive traces on the substrate is approximately 150 to 700 microns/trace. 16. The method of claim 12 wherein the one or more conductive traces includes one or more of a working electrode, a counter electrode or a reference electrode. 17. The method of claim 12 wherein the volume of sample is a blood sample. 18. The method of claim 12 further comprising: providing a sensing layer in contact with the one or more conductive traces. 19. A method of manufacturing an in vitro sensor for the determination of the presence and/or level of glucose in a sample, the method comprising: providing a substrate;disposing a conductive material on the substrate to provide one or more traces, at least one trace having a width of about 25 microns to 250 microns; andforming a sample chamber in the substrate to define the in vitro sensor, wherein the presence and/or the level of glucose is determined with a volume of sample of about 1 microliter or less withdrawn from a subject and received in the formed sample chamber in the substrate of the in vitro sensor. 20. The method of claim 19 wherein the volume of sample includes a blood sample withdrawn from the subject. 21. The method of claim 19 wherein the disposing the conductive material includes disposing one or more of gold, palladium, carbon or conducting polymer on the substrate. 22. The method of claim 19 wherein the one or more traces are provided on the substrate using a laser. 23. The method of claim 19 including two or more conductive traces. 24. The method of claim 23 wherein the two or more conductive traces are separated by a distance of approximately 150 microns or less. 25. The method of claim 19 wherein the one or more conductive traces includes one or more of a working electrode, a counter electrode or a reference electrode. 26. The method of claim 25 wherein at least a portion of the working electrode is in fluid contact with the volume of sample in the sample chamber. 27. The method of claim 26 wherein the at least the portion of the working electrode is in the sample chamber. 28. The method of claim 19 further comprising: providing a sensing layer in contact with the one or more conductive traces. 29. The method of claim 28 wherein the one or more conductive traces in contact with the sensing layer includes a working electrode. 30. The method of claim 19 further comprising disposing a sorbent material within the sample chamber.
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