초록 ▼

A medical device, such as a stent, is disclosed having a modified surface. A method of making the modification is also disclosed. The modification includes depositing a substance within the surface of the device and forming a film layer on the surface of the device. The substance can include carbon

A medical device, such as a stent, is disclosed having a modified surface. A method of making the modification is also disclosed. The modification includes depositing a substance within the surface of the device and forming a film layer on the surface of the device. The substance can include carbon and the film layer can be a polymeric layer, such as a plasma polymerized organic film layer.

대표청구항 ▼

1. A stent comprising: a metallic stent body having a stent body surface;a molecular carbon deposit present at a depth of not more than about 2000 Å beneath the stent body surface; anda plasma-polymerized polymer film layer deposited over the stent body surface and in intimate contact with the stent

1. A stent comprising: a metallic stent body having a stent body surface;a molecular carbon deposit present at a depth of not more than about 2000 Å beneath the stent body surface; anda plasma-polymerized polymer film layer deposited over the stent body surface and in intimate contact with the stent body surface, wherein the plasma-polymerized film layer is chemically bonded to the carbon deposit. 2. The stent of claim 1, wherein the plasma-polymerized polymer film layer comprises an acrylate. 3. The stent of claim 1, wherein the plasma-polymerized polymer film layer is formed by exposing the stent to an acrylic acid plasma. 4. The stent of claim 1, wherein the plasma polymerized film layer comprises functional groups selected from the group consisting of carboxylate, amine and sulfate. 5. The stent of claim 1, wherein the surface of the stent is the tissue-contacting surface of the stent body. 6. The stent of claim 1, wherein the metallic stent body comprises stainless steel. 7. The stent of claim 1, further comprising a polymeric layer comprising a therapeutic substance formed on the plasma-polymerized polymer film layer. 8. The stent of claim 1, wherein the metallic stent body comprises a radially expandable tubular body. 9. The stent of claim 1, wherein the metallic stent body comprises an alloy.