Auto-titration bi-level pressure support system and method of using same
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A61M-015/00
A61M-016/00
A61F-005/56
출원번호
US-0924259
(2007-10-25)
등록번호
US-8136521
(2012-03-20)
발명자
/ 주소
Matthews, Greg
Duff, Winslow K
Martin, Daniel
Shankar, Uday S
Ressler, Heather
출원인 / 주소
RIC Investments, LLC
대리인 / 주소
Haas, Michael W.
인용정보
피인용 횟수 :
13인용 특허 :
37
초록▼
A bi-level pressure support system and method of treating disordered breathing that optimizes the pressure delivered to the patient during inspiration and expiration to treat the disordered breathing while minimizing the delivered pressure for patient comfort. The pressure generating system generate
A bi-level pressure support system and method of treating disordered breathing that optimizes the pressure delivered to the patient during inspiration and expiration to treat the disordered breathing while minimizing the delivered pressure for patient comfort. The pressure generating system generates a flow of breathing gas at an inspiratory positive airway pressure (IPAP) during inspiration and at an expiratory positive airway pressure (EPAP) during expirations. A controller monitor at least one of the following conditions: (1) snoring, (2) apneas, (3) hypopneas, or (4) a big leak in the pressure support system and adjusts the IPAP and the EPAP based on the occurrence of any one of these conditions.
대표청구항▼
1. An auto-titration pressure support system comprising: a pressure generating system adapted to generate a flow of breathing gas at a selectable pressure level;a patient circuit having a first end adapted to be coupled to the pressure generating system and a second end adapted to be coupled to an a
1. An auto-titration pressure support system comprising: a pressure generating system adapted to generate a flow of breathing gas at a selectable pressure level;a patient circuit having a first end adapted to be coupled to the pressure generating system and a second end adapted to be coupled to an airway of a patient;a monitoring system associated with the patient circuit or the pressure generating system and adapted to measure a parameter indicative of a flow of gas in such a patient's airway and to output a flow signal indicative thereof; anda controller coupled to the monitoring system and the pressure generating system, for controlling the pressure generating system based on the output of the monitoring system, wherein for each of a plurality of different monitored breath parameters the controller determines a plurality of values for the monitored breath parameter over a period of time and performs a long-term trend analysis and a short-term trend analysis on the plurality of values for the monitored breath parameter, wherein a result of the long-term trend analysis and the short-term trend analysis for each monitored breath parameter are used by the controller to determine a trend analysis vote associated with each monitored breath parameter, wherein the trend analysis votes for each of the monitored breath parameters are accumulated to determine a final vote value, and wherein the controller causes the pressure generating system to adjust the pressure level of the flow of breathing gas based on the final vote value. 2. The system of claim 1, wherein for each monitored breath parameter each value is an average determined over a number of different respiratory cycles. 3. An auto-titration pressure support system comprising: a pressure generating system adapted to generate a flow of breathing gas at a selectable pressure level;a patient circuit having a first end adapted to be coupled to the pressure generating system and a second end adapted to be coupled to an airway of a patient;a monitoring system associated with the patient circuit or the pressure generating system and adapted to measure a parameter indicative of a flow of gas in such a patient's airway and to output a flow signal indicative thereof; anda controller coupled to the monitoring system and the pressure generating system, for controlling the pressure generating system based on the output of the monitoring system, wherein the controller performs a trend analysis on the output of the monitoring system, wherein the controller determines one value for a monitored breath parameter for each respiratory cycle and averages a plurality of the values for the monitored breathing parameter to determine a single point value, wherein the controller uses a plurality of the single points values in performing the trend analysis, and wherein the controller determines a best-fit line for the plurality of the single point values and calculates a percent change of the best-fit line, a difference value for the best-fit line, or both. 4. An auto-titration pressure support system comprising: a pressure generating system adapted to generate a flow of breathing gas at a selectable pressure level;a patient circuit having a first end adapted to be coupled to the pressure generating system and a second end adapted to be coupled to an airway of a patient;a monitoring system associated with the patient circuit or the pressure generating system and adapted to measure a parameter indicative of a flow of gas in such a patient's airway and to output a flow signal indicative thereof; anda controller coupled to the monitoring system and the pressure generating system, for controlling the pressure generating system based on the output of the monitoring system, wherein the controller performs a trend analysis on the output of the monitoring system, wherein the controller determines one value for a monitored breath parameter for each respiratory cycle and averages a plurality of the values for the monitored breathing parameter to determine a single point value, wherein the controller uses a plurality of the single points values in performing the trend analysis, and wherein the controller performs a long-term trend analysis by determining a trend error window for a best-fit line for the plurality of the single point values and comparing the trend error window to at least one threshold. 5. An auto-titration pressure support system comprising: a pressure generating system adapted to generate a flow of breathing gas at a selectable pressure level;a patient circuit having a first end adapted to be coupled to the pressure generating system and a second end adapted to be coupled to an airway of a patient;a monitoring system associated with the patient circuit or the pressure generating system and adapted to measure a parameter indicative of a flow of gas in such a patient's airway and to output a flow signal indicative thereof; anda controller coupled to the monitoring system and the pressure generating system, for controlling the pressure generating system based on the output of the monitoring system, wherein the controller performs a trend analysis on the output of the monitoring system, wherein the controller determines one value for a monitored breath parameter for each respiratory cycle and averages a plurality of the values for the monitored breathing parameter to determine a single point value, wherein the controller uses a plurality of the single points values in performing the trend analysis, and wherein the controller performs a short-term trend analysis by (1) comparing a newly generated single point value to a prediction interval, wherein the prediction interval is determined by the controller based at least in part on a standard deviation of single point values used in determining a best-fit line for the plurality of single point values and (2) comparing a newly generated single point value to a start of trend data point, which is a single point value on the best-fit line at a start of data used in determining the best-fit line. 6. An auto-titration pressure support system comprising: a pressure generating system adapted to generate a flow of breathing gas at a selectable pressure level;a patient circuit having a first end adapted to be coupled to the pressure generating system and a second end adapted to be coupled to an airway of a patient;a monitoring system associated with the patient circuit or the pressure generating system and adapted to measure a parameter indicative of a flow of gas in such a patient's airway and to output a flow signal indicative thereof; anda controller coupled to the monitoring system and the pressure generating system, for controlling the pressure generating system based on the output of the monitoring system, wherein the controller determines a plurality of values of a weighted peak flow of the patient over a period of time from the flow signal, and wherein the controller analyzes a variability of the weighted peak flow and controls the pressure generating system based on a result of the variability analysis. 7. The system of claim 6, wherein the controller analyzes the variability of the weighted peak flow based on a standard deviation of the plurality of values of the weighted peak flow, the standard deviation being based on a best fit line trend line for the plurality of values of the weighted peak flow. 8. The system of claim 7, wherein the controller analyzes the variability of the weighted peak flow based on the standard deviation and an adjusted mean flow of the patient. 9. An auto-titration pressure support system comprising: a pressure generating system adapted to generate a flow of breathing gas at a selectable pressure level;a patient circuit having a first end adapted to be coupled to the pressure generating system and a second end adapted to be coupled to an airway of a patient;a monitoring system associated with the patient circuit or the pressure generating system and adapted to measure a parameter indicative of a pressure at a patient's airway and a flow of gas in such a patient's airway and to output a pressure signal and a flow signal indicative thereof; anda controller coupled to the monitoring system and the pressure generating system, for controlling the pressure generating system based on the output of the monitoring system, wherein the controller monitors leakage of gas from the patient circuit based on the flow signal, the pressure signal, or both and reduces a pressure provided to a patient by the pressure generating system for a predetermined period of time responsive to a determination that a rate of the leakage of gas exceeds a predetermined threshold, and wherein the controller continues to deliver a therapeutic pressure support treatment to the patient by causing the pressure generating system to continue to deliver the flow of breathing gas at a reduced level that is a level sufficient to provide a therapeutic treatment to such a patient. 10. An auto-titration pressure support system comprising: a pressure generating system adapted to generate a flow of breathing gas at a selectable pressure level;a patient circuit having a first end adapted to be coupled to the pressure generating system and a second end adapted to be coupled to an airway of a patient;a monitoring system associated with the patient circuit or the pressure generating system and adapted to measure a parameter indicative of a flow of gas in such a patient's airway and to output a flow signal indicative thereof; anda controller coupled to the monitoring system and the pressure generating system, for controlling the pressure generating system based on the output of the monitoring system, wherein the controller determines a skewness of a patient's inspiratory waveforms from the output of the flow sensor and controls the pressure generating system according to the skewness determination. 11. An auto-titration pressure support system comprising: a pressure generating system adapted to generate a flow of breathing gas at a selectable pressure level;a patient circuit having a first end adapted to be coupled to the pressure generating system and a second end adapted to be coupled to an airway of a patient;a monitoring system associated with the patient circuit or the pressure generating system and adapted to measure a parameter indicative of a flow of gas in such a patient's airway and to output a flow signal indicative thereof; anda controller coupled to the monitoring system and the pressure generating system, for controlling the pressure generating system based on the output of the monitoring system, wherein the controller is programmed determine whether the patient is experiencing a central apnea/hypopnea or an obstructive/restrictive apnea/hypopnea by monitoring one or more of the following: (1) at least one shape parameter associated with the flow of gas during an apnea/hypopnea period, and (2) a characteristic of the flow of gas at the end of the apnea/hypopnea period indicative of an increase in respiratory effort. 12. The system of claim 11, wherein the shape parameters monitored by the controller during an apnea/hypopnea period include a flatness of an inspiratory portion of a flow waveform, a roundness of the inspiratory portion of the flow waveform, a skewness of the inspiratory portion of the flow waveform.
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이 특허에 인용된 특허 (37)
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Matthews, Greg; Duff, Winslow K; Martin, Daniel; Shankar, Uday S; Ressler, Heather, Auto-titration bi-level pressure support system and method of using same.
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