초록 ▼

The present invention relates generally to medical devices and methods for sealing and closing passages formed through tissue. More specifically, the present invention relates to devices for sealing or closing an opening formed through biological tissue comprising a distal or outside margin or surfa

The present invention relates generally to medical devices and methods for sealing and closing passages formed through tissue. More specifically, the present invention relates to devices for sealing or closing an opening formed through biological tissue comprising a distal or outside margin or surface, and a proximal or inside margin or surface (i.e., a wall thickness), and to apparatuses and methods for delivering such devices, to control (or prevent or stop) bleeding (or the flow of other biological fluid or tissue). The openings comprise percutaneously formed punctures, incisions, or other openings formed through biological tissue, such as in blood vessels, organs, and the like.

대표청구항 ▼

1. A closure device for sealing an opening formed through biological tissue, said closure device comprising: (a) a plug comprising a proximal end and a distal end;(b) a rigid wire extending from a position distal to said plug's distal end through said plug and comprising a plastically deformed bend

1. A closure device for sealing an opening formed through biological tissue, said closure device comprising: (a) a plug comprising a proximal end and a distal end;(b) a rigid wire extending from a position distal to said plug's distal end through said plug and comprising a plastically deformed bend that is positioned in secure engagement with said proximal end of said plug; and(c) a footplate attached to said wire, and positioned distally to said distal end of said plug. 2. The closure device of claim 1, wherein at least one of said plug, said wire, and said footplate is at least partially formed of a biocorrodible metal. 3. The closure device of claim 2, wherein said biocorrodible metal comprises magnesium. 4. The closure device of claim 2, wherein said biocorrodible metal comprises a magnesium alloy. 5. The closure device of claim 4, wherein said magnesium alloy is AZ31. 6. The closure device of claim 1, wherein said plug includes a passageway through which the wire extends. 7. The closure device of claim 6, wherein said plug is movable along said wire. 8. The closure device of claim 1, wherein said plug comprises a first portion having a first dimension and a second portion having a second dimension that is greater than the first dimension. 9. The closure device of claim 8, wherein said footplate is positioned distally to the first portion of said plug and said deformable portion is positioned proximally to the second portion of said plug. 10. The closure device of claim 8, wherein said plug is substantially conically-shaped. 11. The closure device of claim 10, wherein said plug comprises a distal surface at said distal end and a proximal surface at said proximal end, wherein an area of said plug's distal surface is smaller than an area of said plug's proximal surface. 12. The closure device of claim 11, said wire further comprising a longitudinal axis, and said plastically deformed bend is bent at about a 30 to 90 degree angle from said longitudinal axis. 13. The closure device of claim 1, wherein said footplate is a substantially looped distal portion of the wire. 14. The closure device of claim 1, wherein said footplate comprises an elongated plate portion attached to a distal end of said wire, and an aperture formed therethrough. 15. The closure device of claim 1, wherein said footplate comprises a longitudinally shaped plate portion, and is hingedly attached to a distal end of said wire. 16. The closure device of claim 1, wherein said wire comprises a tensile element selected from the group consisting of a monofilament and a multifilament. 17. The closure device of claim 1, wherein said footplate and said plug are biodegradable. 18. The closure device of claim 17, wherein said footplate biodegrades at a rate greater than that of said plug, such that the footplate completely biodegrades prior to the complete biodegradation of said plug.