IPC분류정보
국가/구분 |
United States(US) Patent
등록
|
국제특허분류(IPC7판) |
|
출원번호 |
US-0373347
(2007-07-11)
|
등록번호 |
US-8151599
(2012-04-10)
|
우선권정보 |
DE-10 2006 032 435 (2006-07-13) |
국제출원번호 |
PCT/EP2007/006138
(2007-07-11)
|
§371/§102 date |
20090112
(20090112)
|
국제공개번호 |
WO2008/006558
(2008-01-17)
|
발명자
/ 주소 |
|
출원인 / 주소 |
|
대리인 / 주소 |
|
인용정보 |
피인용 횟수 :
2 인용 특허 :
16 |
초록
▼
The invention relates to a transport container (1) comprising a superinsulation in the form of an evacuated insulating container (2) comprising a vacuum maintaining material (55). The transport container is provided with a cooling container (16) comprising a heat-conducting metal wool filling (57) a
The invention relates to a transport container (1) comprising a superinsulation in the form of an evacuated insulating container (2) comprising a vacuum maintaining material (55). The transport container is provided with a cooling container (16) comprising a heat-conducting metal wool filling (57) and an organic coolant which undergoes a solid/liquid phase change in the temperature range of between −30° C. and −850° C. and has a heat of fusion of at least 50 J/ml. A slim cylindrical sample chamber (24) is used to receive deep-frozen tissue samples (26), said chamber being surrounded by the cooling container (16) and merging into a long neck opening (25) forming a single component therewith, said opening being largely filled by the insulating shaft (30) of a screwable plug (28) and sealed from the sample chamber (24). The air in the ring gap (32) created can be evacuated by means of an evacuating system (48). The plug (28) is provided with a stopper (38) protruding into the sample chamber (24) and a data logger (41) for recording the temperature in the sample chamber (24). Following the freezing of the coolant, the transport container (1) enables distribution times and intermediate storage of up to 14 days without any risk of damage to the tissue samples (26) received therein.
대표청구항
▼
1. A transport container for maintaining a temperature of frozen goods (26), comprising a) an insulation container (2), whichb) is accessible via an insulating cover part (45) andc) has superinsulation with a thermal conductivity λ≦0.002 W/(mK);d) a cooling container (16) comprising a coolant chambe
1. A transport container for maintaining a temperature of frozen goods (26), comprising a) an insulation container (2), whichb) is accessible via an insulating cover part (45) andc) has superinsulation with a thermal conductivity λ≦0.002 W/(mK);d) a cooling container (16) comprising a coolant chamber (21) arranged in the insulation container (2), which coolant chambere) surrounds a sample chamber (24) for the frozen goods (26) except for an access opening (25) on a fastener side,f) is permanently hermetically sealed andg) comprises a coolant whichh) emits cold by solid/liquid phase transition,i) undergoes phase transition in a temperature range between −15° and −100° C. andj) has a heat of fusion of at least 50 J/ml, whereink) the cooling container (16) comprises a coolant chamber (21) is fixedly integrated in the insulation container (2);l) the insulation container (2) extends beyond the sample chamber (24) by a length which exceeds its transverse dimensions by at least a factor of three by forming a neck-shaped opening (25);m) on an outer end of the neck opening (25), provision is made for an insulation ring (15) whichn) insulates an inner wall (3) and an outer wall (4) of the insulation container (2) from each other, ando) elastically mounts the inner wall (3) with the connected cooling container (16) with respect to the outer wall (4),p) a plug (28) being assigned to a cover part (45) and whichq) extends into the neck-shaped opening (25) with an insulation shaft (30),r) fills the neck-shaped opening (25) substantially over its entire length, ands) is sealed from the inner wall (3) of the insulation container (2) on a protruding end by means of a neck seal (33);t) a container seal (9) is arranged between the insulation container (2) and the cover part (45), andu) an evacuation apparatus (48) is provided for evacuating a cover interior (47), including an annular gap (32) surrounding the insulation shaft (30). 2. The transport container as claimed in claim 1, wherein the coolant is an organic pure substance with a phase transition temperature between −30° and −85° C. 3. The transport container as claimed in claim 1, wherein the insulation container (2) is designed in a hollow-cylindrical fashion with an outer base (6) adjoining the outer wall (4), and the inner wall (3), which simultaneously forms an inner peripheral wall (20) of the cooling container (16) and defines the sample chamber (24), merges at an inner end into a chamber base (11) which is arranged in a gap distance to an inner base (5) of the insulation container (2) which forms a cooling container base. 4. The transport container as claimed in claim 1, wherein the insulation container (2) is provided with an evacuation apparatus (51) for purposes of vacuum insulation, and is filled with a vacuum-supporting material (55). 5. The transport container as claimed in claim 4, wherein the insulation container (2) is filled with powdered pyrogenic silicic acid as a vacuum-supporting material (55). 6. The transport container as claimed in claim 4, wherein a getter (56) is installed in the insulation container (2). 7. The transport container as claimed in claim 1, wherein the plug (28) comprising the insulation shaft (30) is a separate component. 8. The transport container as claimed in claim 7, wherein the plug (28) is designed as a screw plug which interacts with a female thread (13) at an outer end of the neck opening (25). 9. The transport container as claimed in claim 7, wherein the plug (28) comprises a head (29) which is widened compared to the insulation shaft (30) and which is held in a recess in the cover part (45). 10. The transport container as claimed in claim 9, wherein a head (29) of the plug (28) contains a data logger (41) and a battery (42) assigned to the latter, with the data logger (41) being connected to a temperature sensor (44) in a region of a free end of the insulation shaft (30) via a signal line (43) guided through the insulation shaft (30). 11. The transport container as claimed in claim 1, wherein the insulation shaft (30) comprises at least one annular groove (36) with an O-ring (35) for sealing it with respect to the inner wall (3) of the insulation container (2) and for subdividing the annular gap (32) between the inner wall (3) and the insulation shaft (30). 12. The transport container as claimed in claim 1, wherein on its protruding end which delimits the sample chamber (24), the plug (28) has a replaceable pad (38) for absorbing sample chamber liquids. 13. The transport container as claimed in claim 1, wherein in addition to the coolant, the coolant chamber (21) of the cooling container (16) also comprises a thermally conducting metal wool filling (57) for improved cold-loading prior to receiving the frozen goods (26). 14. The transport container as claimed in claim 1, wherein the coolant is an organic substance. 15. The transport container as claimed in claim 1, wherein the insulation container (2) and the cooling container (16) are composed of stainless steel. 16. The transport container as claimed in claim 1 wherein it is assigned surrounding packaging (58), comprising an insulating outer container (59) and an insulating outer cover (60), which surrounds a reception chamber (66) whose dimensions correspond to those of the transport container (1). 17. The transport container as claimed in claim 16, wherein the outer container (59) comprises a coolant (67) with a liquid/solid phase transition in a temperature range between 0° and −15° C. 18. The transport container as claimed in claim 1, wherein it is assigned a cold-loading apparatus which comprises a thermally highly conducting solid cooling finger (80, 88, 90), comprising copper in particular, whose length corresponds to a sum of lengths of the sample chamber (24) and neck opening (25), and whose transverse dimensions are matched to the sample chamber (24) and neck opening (25), with one end of a cooling finger (80, 88, 90) being connected to a cold transfer device (78, 87, 89). 19. The transport container as claimed in claim 18, wherein the cold transfer device (78) is a vessel (79, 81, 82) provided with outer insulation (85) for holding a low temperature coolant (84), such as liquid nitrogen or dry ice. 20. The transport container as claimed in claim 19, wherein the cooling finger (80) extends upwardly and centrally from a base (79) of the vessel (79, 81, 82) which has an outer annular chamber (83) for the coolant (84) and an inner chamber for holding the insulation container (2) which in turn is pushed onto the cooling finger (80) with a downward-pointing neck opening (25). 21. The transport container as claimed in claim 18, wherein the cold transfer device (89) is provided with lamellae (91) for increased heat transfer during cold-loading in a deep-freezer. 22. The transport container as claimed in claim 18, wherein the cooling finger is pressed against a sample chamber base (11) and dynamically tracked, so that an end side fixedly rests against the latter. 23. The transport container as claimed in claim 1, wherein it is assigned a filling-funnel (76) for direct cold-loading with a low temperature cooling medium (75), with the filling-funnel (76) being able to be screwed into a female thread (13) at an outer end of the neck opening (25).
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