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A clip device (1612) for hemostasis includes a clip having a plurality of arms (1640, 1650) each having a proximal end and a distal end, wherein each of the arms are spaced apart from each other when the clip is in an open position and adjacent to each other when the clip is in a closed position. At

A clip device (1612) for hemostasis includes a clip having a plurality of arms (1640, 1650) each having a proximal end and a distal end, wherein each of the arms are spaced apart from each other when the clip is in an open position and adjacent to each other when the clip is in a closed position. At least one lumen (1643, 1653) is disposed within a first of the plurality of arms and spans from the proximal end to the distal end of the first arm. At least one outlet bore is formed in the distal end of the first arm. In use, the distal ends of the plurality of arms are adapted to engage tissue in the closed position, and a sclerosing agent is adapted to be delivered to tissue via the lumen and an outlet bore formed in the first arm. Such technique facilitates treatment of the underlying bleeding using a combination of mechanical and sclerotherapy approaches.

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1. A clip device for use in endoscopic medical procedures comprising: a clip having a plurality of arms each having a proximal end and a distal end, wherein the proximal end of each of the arms is joined to a first retainer and extends distally therefrom, wherein each of the arms are spaced apart fr

1. A clip device for use in endoscopic medical procedures comprising: a clip having a plurality of arms each having a proximal end and a distal end, wherein the proximal end of each of the arms is joined to a first retainer and extends distally therefrom, wherein each of the arms are spaced apart from each other when the clip is in an open position and adjacent to each other when the clip is in a closed position;at least one lumen disposed within at least a first of the plurality of arms, wherein the lumen spans from the proximal end to the distal end of the first arm; andat least one outlet bore formed in the distal end of the first arm,wherein the distal ends of the plurality of arms are adapted to engage tissue in the closed position, and wherein a sclerosing agent is adapted to be delivered to the tissue via the lumen and the outlet bore in the first arm wherein the first retainer comprises a lumen formed therein, the lumen of the first retainer being in fluid communication with the lumen disposed within the first of the plurality of arms, and further comprising a second retainer adapted to be coupled to the first retainer, wherein the first retainer is configured to be coupled to the second retainer prior to deployment of the clip, and wherein the first retainer is configured to be disengaged from the second retainer after the clip is deployed. 2. The clip device of claim 1 wherein each of the plurality of arms comprises at least one lumen formed therein that spans from the proximal end to the distal end of each respective arm. 3. The clip device of claim 1 wherein the distal ends of the plurality of arms are bent radially inward to facilitate grasping of the tissue. 4. The clip device of claim 1 wherein the distal ends of each of the plurality of arms are beveled to form a sharpened tip. 5. The clip device of claim 1 wherein the second retainer comprises at least one lumen formed therein, wherein the lumen of the second retainer is adapted to be placed in fluid communication with the lumen of the first retainer when the second retainer is coupled to the first retainer. 6. The clip device of claim 1 wherein the second retainer comprises proximal and distal regions, wherein an outer diameter of the distal region is smaller than an outer diameter of the proximal region, and wherein the distal region is adapted to be disposed within the lumen of the first retainer. 7. The clip device of claim 1 further comprising: internal threading disposed in the lumen of the first retainer; andexternal threading disposed on the distal region of the second retainer and configured to engage the internal threading, wherein rotation of the second retainer causes the external threading to disengage from the internal threading. 8. A clip device for use in endoscopic medical procedures comprising: a clip having a plurality of arms each having a proximal end and a distal end, wherein the proximal end of each of the arms is joined to a first retainer and extends distally therefrom;a lumen disposed within at least a first of the plurality of arms, wherein the lumen spans from the proximal end to the distal end of the first arm; anda second retainer adapted to be coupled to the first retainer prior to deployment of the clip, wherein the second retainer is configured to be disengaged from the first retainer after the clip is deployed,wherein the first retainer and the second retainer each comprise a lumen formed therein, the lumens of the first and second retainers being in fluid communication with the lumen disposed within the first arm for delivering a sclerosing agent to a tissue site after the first arm engages the tissue site. 9. The clip device of claim 8 wherein each of the arms are formed of a resilient material and shaped so that the distal ends tend to be spaced apart from each other when the clip is in an open position and adjacent to each other when the clip is in a closed position. 10. The clip device of claim 8 wherein each of the plurality of arms comprises a lumen formed therein that spans from the proximal end to the distal end of each respective arm. 11. The clip device of claim 8 wherein the distal ends of the plurality of arms are bent radially inward to facilitate grasping of the tissue site. 12. The clip device of claim 8 wherein the distal ends of each of the plurality of arms are beveled to form a sharpened tip. 13. The clip device of claim 8 wherein the second retainer comprises proximal and distal regions, wherein an outer diameter of the distal region is smaller than an outer diameter of the proximal region, wherein the distal region is adapted to be disposed within the lumen of the first retainer. 14. The clip device of claim 13 further comprising: internal threading disposed in the lumen of the first retainer; andexternal threading disposed on the distal region of the second retainer and configured to engage the internal threading, wherein rotation of the second retainer causes the external threading to disengage from the internal threading.