최소 단어 이상 선택하여야 합니다.
최대 10 단어까지만 선택 가능합니다.
다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
NTIS 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
DataON 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
Edison 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
Kafe 바로가기국가/구분 | United States(US) Patent 등록 |
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국제특허분류(IPC7판) |
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출원번호 | US-0734178 (2007-04-11) |
등록번호 | US-8160669 (2012-04-17) |
발명자 / 주소 |
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출원인 / 주소 |
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대리인 / 주소 |
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인용정보 | 피인용 횟수 : 62 인용 특허 : 556 |
The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.
1. A system for monitoring a glucose concentration in a host, the system comprising: a continuous glucose sensor configured to produce a signal indicative of a glucose concentration in a host;monitoring system electronics operably connected to the sensor and configured to receive reference data from
1. A system for monitoring a glucose concentration in a host, the system comprising: a continuous glucose sensor configured to produce a signal indicative of a glucose concentration in a host;monitoring system electronics operably connected to the sensor and configured to receive reference data from a single point glucose measuring device, the single point glucose measuring device configured to receive a biological sample from the host and to measure a concentration of glucose in the biological sample, wherein the reference data is indicative of a measured glucose concentration in the biological sample, wherein the monitoring system electronics are configured to provide real-time calibrated glucose concentration values of the host based on the signal, and wherein providing the real-time calibrated glucose concentration values comprises evaluating an acceptability of the reference data in real time using a clinical acceptability grid, and calibrating or confirming the signal responsive to the acceptability evaluation of the reference data. 2. The system of claim 1, wherein the monitoring system electronics comprise a user interface, and wherein the monitoring system electronics are further configured to display real-time glucose concentration information on the user interface based on the real-time calibrated glucose concentration values. 3. The system of claim 1, wherein the system further comprises a receiver and wherein the monitoring system electronics are housed within the receiver. 4. The system of claim 3, wherein the reference glucose measuring device is built into the receiver, the single point glucose measuring device having a port configured to accept the biological sample. 5. The system of claim 3, wherein the reference glucose measuring device is separate from the receiver and wherein the receiver includes a user interface configured to accept manual input from a user indicative of a value of the reference data. 6. The system of claim 1, wherein the clinical acceptability grid is one of a Clarke Error grid and a Consensus grid. 7. The system of claim 1, wherein the clinical acceptability grid provides an indication of a clinical acceptability of a disparity between a reference value of the reference data and a sensor value of the signal. 8. The system of claim 7, wherein the reference value and the sensor value are in units of glucose concentration. 9. The system of claim 1, wherein the monitoring system electronics are configured to calibrate or confirm the signal using the reference data only if the acceptability module determines that the reference data is acceptable. 10. A system comprising one or more processors and computer readable memory, the computer readable memory comprising code that, when executed by the one or more processors, causes the one or more processors to: process a signal received from a continuous glucose measuring device;measure a concentration of glucose in a biological sample received from a host, the measured glucose concentration in the sample comprising reference data; andprovide real-time calibrated glucose concentration values of the host based on the signal,wherein providing the real-time calibrated glucose concentration values comprises evaluating an acceptability of the reference data in real time using a clinical acceptability grid, and calibrating or confirming the signal responsive to the acceptability evaluation of the reference data. 11. The system of claim 10, wherein the system further comprises a receiver and wherein the one or more processors and computer-readable memory are housed within the receiver. 12. The system of claim 11, wherein the reference glucose measuring device is built into the receiver, the single point glucose measuring device having a port configured to accept the biological sample. 13. The system of claim 11, wherein the reference glucose measuring device is separate from the receiver and wherein the receiver includes a user interface configured to accept manual input from a user indicative of a value of the reference data. 14. The system of claim 10, wherein the clinical acceptability grid is one of a Clarke Error grid and a Consensus grid. 15. The system of claim 10, wherein the clinical acceptability grid provides an indication of a clinical acceptability of a disparity between a reference value of the reference data and a sensor value of the signal. 16. The system of claim 15, wherein the reference value and the sensor value are in units of glucose concentration. 17. The system of claim 10, wherein the code causes the one or more processors to calibrate or confirm the signal using the reference data only if the reference data is determined to be acceptable. 18. The system of claim 10, wherein the code additionally causes, when executed by the one or more processors, the one or more processors to display information indicative of the real-time calibrated glucose concentration values on a user interface of the system. 19. A method for monitoring glucose concentration in a host, the method comprising: generating a signal from a continuous glucose measuring device indicative of a glucose concentration in a host;measuring a concentration of glucose in a biological sample in a single point glucose measuring device, the measured glucose concentration in the biological sample comprising reference data;providing, using monitoring system electronics of a monitoring system, real-time calibrated glucose concentration values of the host based on the signal, wherein providing the real-time calibrated glucose concentration values comprises evaluating an acceptability of the reference data in real time using a clinical acceptability grid and calibrating or confirming the signal responsive to the acceptability evaluation of the reference data. 20. The method of claim 19, wherein the monitoring system further comprises a receiver and wherein the monitoring system electronics are housed within the receiver. 21. The method of claim 20, wherein the single point glucose measuring device is built into the receiver, the single point glucose measuring device having a port configured to accept the biological sample. 22. The method of claim 20, wherein the reference glucose measuring device is separate from the receiver and wherein the method further comprises receiving manual input using the receiver indicative of a value of the reference data. 23. The method of claim 19, wherein the clinical acceptability grid is one of a Clarke Error grid and a Consensus grid. 24. The method of claim 19, wherein the clinical acceptability grid provides an indication of a clinical acceptability of a disparity between a reference value of the reference data and a sensor value of the signal. 25. The method of claim 24, wherein the reference value and the sensor value are in units of glucose concentration. 26. The method of claim 19, wherein calibrating or confirming the signal only uses reference data that is determined to be acceptable in the acceptability evaluation.
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