최소 단어 이상 선택하여야 합니다.
최대 10 단어까지만 선택 가능합니다.
다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
NTIS 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
DataON 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
Edison 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
Kafe 바로가기국가/구분 | United States(US) Patent 등록 |
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국제특허분류(IPC7판) |
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출원번호 | US-0872071 (2004-06-17) |
등록번호 | US-8162963 (2012-04-24) |
발명자 / 주소 |
|
출원인 / 주소 |
|
대리인 / 주소 |
|
인용정보 | 피인용 횟수 : 6 인용 특허 : 249 |
Anastomosis devices, tools and methods of performing angled sutureless anastomosis. Devices provided are adapted to be oriented at an acute angle to a host vessel or organ, thereby orienting a graft to be anastomosed to the host by the same angle. The device maintains the angular orientation as it i
Anastomosis devices, tools and methods of performing angled sutureless anastomosis. Devices provided are adapted to be oriented at an acute angle to a host vessel or organ, thereby orienting a graft to be anastomosed to the host by the same angle. The device maintains the angular orientation as it is compressed to join the graft and host.
1. A device for use in making an angled anastomosis between first and second tubular fluid conduits in the body of a patient, said device comprising: a unitary structure having a main body disposed annularly about a longitudinal axis, having a proximal end portion with a proximal end, and a distal e
1. A device for use in making an angled anastomosis between first and second tubular fluid conduits in the body of a patient, said device comprising: a unitary structure having a main body disposed annularly about a longitudinal axis, having a proximal end portion with a proximal end, and a distal end portion with a distal end, and adapted for passing the first tubular conduit through an annulus defined by the main body;an exterior of said main body configured to be inserted through an opening in the second tubular conduit;at least one first member extending radially from said proximal end portion and, in an undeformed configuration, angled toward a proximal direction of said device, relative to said longitudinal axis, and at least one second member extending radially, in said undeformed configuration, from said proximal end portion and angled toward a distal direction of said device, relative to said longitudinal axis, said members extending from said proximal end portion configured to abut against an external wall of the second conduit upon angulation of said main body with respect to a wall of the second tubular conduit;locking members fixed to said distal end portion and slidably received by said proximal end portion, wherein, upon buckling of said distal end portion, free ends of said locking members slide to extend proximally of said proximal end portion;said distal end portion being configured to buckle in response to axial compression of said device, wherein said distal end portion plastically deforms and is incapable of passing through said opening after buckling and exerts a compressive force between the first conduit and the wall of the second conduit upon buckling, while maintaining the angled configuration of the main body with respect to the second conduit. 2. The device of claim 1, said distal end portion further comprising: conduit retainers, wherein, upon passing the first conduit through said main body, a free end of the first conduit is everted over a distal end of the device and retained by said conduit retainers, and wherein said distal end is angled with respect to a normal to the longitudinal axis. 3. The device of claim 2, wherein said conduit retainers comprise graft tines. 4. The device of claim 1, wherein said distal end portion comprises buckling struts configured to ensure buckling in a radially outward direction upon application of a compressive force thereto. 5. The device of claim 1, wherein said at least one first member and at least one second member extending from said proximal end portion comprises a plurality of at least one of said first and second members extending from a proximal end of said device and oriented substantially parallel to the proximal end. 6. The device of claim 1, wherein said proximal end being uniformly angled with respect to a normal to said longitudinal axis, when said device is in an undeformed configuration, and said proximal end also being angled with respect to a normal to said longitudinal axis when in a deformed, deployed configuration. 7. The device of claim 1, wherein said proximally extending free ends of said locking members are adapted to be bent over against said proximal end portion and the external wall of the second conduit to lock the relative position of said proximal and distal end portions. 8. The device of claim 1, wherein said proximal end portion is variably collapsible to accommodate varying wall thicknesses, so as to make said device adaptable for joining the first conduit to various second conduits having varying wall thicknesses. 9. The device of claim 8, wherein distal and proximal ends of said device are uniformly angled with respect to a normal to the longitudinal axis by a predefined angle, and wherein said distal and proximal ends substantially maintain said predefined angle after buckling of the distal end portion and collapsing of the proximal end portion. 10. The device of claim 9, wherein said predefined angle is in the range of about 30 degrees to about 45 degrees. 11. The device of claim 10, wherein said angulation of the main body and said substantial maintenance of the predefined angles of said distal and proximal ends maintains the first tubular conduit at substantially said predefined angle with respect to the second fluid conduit upon completion of the anastomosis. 12. An anastomosis device comprising: a unitary structure having a main body having an outside diameter adapted to pass through and form a close fit with an opening formed in a wall of a conduit to be joined by anastomosis;said main body defining an annulus having an inside diameter, said annulus extending longitudinally through said body along a longitudinal axis thereof;said body having proximal and distal end portions angled at non-zero angles with respect to a normal to the longitudinal axis and with respect to the longitudinal axis, said proximal and distal end portions having a proximal and distal end, respectively, said distal ends being uniformly angled with respect to said normal and said longitudinal axis and said proximal ends being uniformly angled with respect to said normal and said longitudinal axis;an extension portion extending from said proximal end portion, having a length sufficient to span the length of said main body, and configured to be incapable of passing through the opening;locking members fixed to said distal end portion and slidably received by said proximal end portion, wherein, upon buckling of said distal end portion, free ends of said locking members slide to extend proximally of said proximal end portion; andconduit retainers on said distal end portion adapted to retain a free end portion of a conduit having been passed through said annulus and everted over said proximal end portion. 13. The device of claim 12, wherein said main body is generally in the shape of an oblique cylinder. 14. The device of claim 12, wherein said distal end portion is configured to ensure outward buckling in response to axial compression of said device, and wherein said distal end portion is incapable of passing through the opening after buckling and exerts a compressive force toward said extension portion. 15. The device of claim 14, wherein said distal end portion is adapted to further evert the conduit retained by said conduit retainers upon buckling. 16. The device of claim 12, wherein said proximally extending free ends of said locking members are adapted to be bent over against said proximal end portion to lock the relative position of said proximal and distal end portions. 17. The device of claim 12, wherein said proximal end portion is variably collapsible to accommodate varying wall thicknesses that occur among different patients. 18. A device for use in making an angled anastomosis between tubular fluid conduits in the body of a patient, said device comprising: a unitary structure having a main body disposed annularly about a longitudinal axis and having first and second end portions each encircling an annulus that the longitudinal axis passes through and angled with respect to a normal to the longitudinal axis, said first end portion having a first end angled with respect to the normal to the longitudinal axis, with a location on said first end that is furthest from said normal to the longitudinal axis at a location passing through said main body being opposite to a location on said first end that is nearest to said normal to the longitudinal axis at said location passing through said main body;a plurality of members extending radially outwardly from said first end portion;said second end portion having a plurality of spaced struts adapted to buckle in a radially outward direction upon axial compression of said device, wherein said struts are plastically deformed during buckling; anda plurality of elongated members extending from said second end portion toward said first end portion and adapted to apply a compressive force to said second end portion to buckle said spaced struts wherein each said elongated member comprises a free end portion extending away from said second end portion. 19. The device of claim 18, wherein said first end portion further comprises: a second set of spaced struts axially spaced from said plurality of said spaced struts of said second end portion, said second set of spaced struts being collapsible over a variable range of distance to accommodate for varying wall thicknesses of the tubular conduits being joined by anastomosis. 20. The device of claim 19, wherein an end of said second end portion maintains substantially the same angulation with respect to the normal after buckling of said spaced struts as before buckling. 21. The device of claim 19, wherein said first end portion maintains substantially the same angulation with respect to the normal after collapsing of said second set of spaced struts as before collapsing. 22. The device of claim 19, wherein said second set of struts begins collapsing after said struts of said second end portion have buckled. 23. The device of claim 19, wherein said second set of struts have a higher compression strength than said struts of said second end portion. 24. The device of claim 19, wherein said second set of struts are plastically deformed upon collapsing. 25. The device of claim 18, wherein an end of said second end portion maintains substantially the same angulation with respect to the normal after buckling of said spaced struts as before buckling. 26. The device of claim 18, wherein said first end portion maintains substantially the same angulation with respect to the normal after buckling of said spaced struts as before buckling. 27. The device of claim 18, wherein at least one of said plurality of spaced struts comprises a pair of strut portions of unequal length, wherein said at one strut comprising a unequal length strut portions, upon buckling orients at an angle to a normal to a longitudinal axis of said main body. 28. The device of claim 18, wherein said first end portion further comprises a first ring member angled with respect to the normal, wherein said plurality of members extending radially outwardly from said first end portion extend from said first ring member; and wherein said second end portion comprises a second ring member angled with respect to the normal, wherein said plurality of spaced struts extend from said second ring member toward said first ring member. 29. The device of claim 28, wherein said first and second rings are angled with respect to the normal by substantially the same degree of angulation. 30. The device of claim 28, wherein said plurality of spaced struts connect said second ring member with said first ring member. 31. The device of claim 28, further comprising a plurality of tines extending radially outwardly from said second end portion and adapted to mechanically engage an everted end of a first of the tubular fluid conduits. 32. The device of claim 18, wherein said elongated members extend substantially parallel to the longitudinal axis. 33. The device of claim 18, wherein each said elongated member comprises a weakened portion adapted to fail under tension before the remainder of said elongated member. 34. The device of claim 33, wherein said weakened portions are necked portions. 35. The device of claim 18, wherein each said free end portion extends beyond said first end portion. 36. The device of claim 18, wherein each said free end portion comprises an engagement portion adapted for engagement with a deployment device, for application of tension to said elongated member by the deployment device. 37. The device of claim 18, further comprising a plurality of tines extending radially outwardly from said second end portion. 38. The device of claim 37, wherein said plurality of tines extend from said spaced struts. 39. The device of claim 37, wherein said tines are graft tines adapted to pierce a side wall of one of the conduits to be joined by anastomosis. 40. The device of claim 18, wherein said main body defines an annular space which is configured to slide over the outer wall of one of the two conduits to be joined by anastomosis. 41. The device of claim 18, wherein the second end portion struts, upon buckling are adapted to form a compression fit with said members extending radially outwardly from said first end portion to form a seal between an everted end of one of the tubular fluid conduits and an inner wall of a second of the tubular fluid conduits. 42. The device of claim 41, wherein said first and second end portions maintain substantially the same angulation with respect to the normal after buckling of said spaced struts as before buckling. 43. The device of claim 18, wherein said second end portion comprises an end angled with respect to the normal by an angle less than the angulation of said first end portion with respect to the normal. 44. The device of claim 43, wherein said end of said second end portion is adapted to collapse to a configuration which is angled to the normal at substantially the same angle as the angulation of said first end portion to the normal, prior to buckling of said struts. 45. A device for use in making an angled anastomosis between tubular fluid conduits in the body of a patient, said device comprising: a unitary structure having a main body disposed annularly about a longitudinal axis and having first and second end portions each encircling an annulus that the longitudinal axis passes through and angled with respect to a normal to the longitudinal axis, said first end portion having a first end angled with respect to the normal to the longitudinal axis, with a location on said first end that is furthest from said normal to the longitudinal axis at a location passing through said main body being opposite to a location on said first end that is nearest to said normal to the longitudinal axis at said location passing through said main body;a plurality of members extending radially outwardly from said first end portion; andsaid second end portion having a plurality of spaced struts adapted to buckle in a radially outward direction upon axial compression of said device, wherein said struts are plastically deformed during buckling, wherein at least one of said plurality of spaced struts, upon buckling, buckles at a location along a length of said at least one strut that is different from a relative location at which at least another one of said struts buckles along a length of said at least another one of said struts, whereby said at least one strut orients at an angle in a first direction to the normal to the longitudinal axis of said main body, and said at least another one of said plurality of spaced struts, upon buckling, orients at an angle is a second direction, opposite to said first direction, to the normal to the longitudinal axis of said main body. 46. A device for use in making an angled anastomosis between tubular fluid conduits in the body of a patient, said device comprising: a unitary structure having a main body disposed annularly about a longitudinal axis and having first and second end portions each encircling an annulus that the longitudinal axis passes through and angled with respect to a normal to the longitudinal axis, said first end portion having a first end angled with respect to the normal to the longitudinal axis, with a location on said first end that is furthest from said normal to the longitudinal axis at a location passing through said main body being opposite to a location on said first end that is nearest to said normal to the longitudinal axis at said location passing through said main body;a plurality of members extending radially outwardly from said first end portion; andsaid second end portion having a plurality of spaced struts adapted to buckle in a radially outward direction upon axial compression of said device, wherein said struts are plastically deformed during buckling, wherein at least one of said plurality of spaced struts, upon buckling, orients normal to the longitudinal axis of said main body. 47. A device for use in making an angled anastomosis between tubular fluid conduits in the body of a patient, said device comprising: a unitary structure having a main body disposed annularly about a longitudinal axis and having first and second end portions each encircling an annulus that the longitudinal axis passes through and angled with respect to a normal to the longitudinal axis, said first end portion having a first end angled with respect to the normal to the longitudinal axis, with a location on said first end that is furthest from said normal to the longitudinal axis at a location passing through said main body being opposite to a location on said first end that is nearest to said normal to the longitudinal axis at said location passing through said main body;a plurality of members extending radially outwardly from said first end portion; andsaid second end portion having a plurality of spaced struts adapted to buckle in a radially outward direction upon axial compression of said device, wherein said struts are plastically deformed during buckling;wherein said first end portion further comprises:a second set of spaced struts axially spaced from said plurality of said spaced struts of said second end portion, said second set of spaced struts being collapsible over a variable range of distance to accommodate for varying wall thicknesses of the tubular conduits being joined by anastomosis; andwherein said first end portion further comprises a first ring member angled with respect to the normal, wherein said plurality of members extending radially outwardly from said first end portion extend from said first ring member; and wherein said second end portion comprises a second ring member angled with respect to the normal; and further comprising a third ring member intermediate of said first and second ring members and angled with respect to the normal, wherein said plurality of spaced struts extend from said second ring member to said third ring member; and wherein said second set of spaced struts extend from said first ring member to said third ring member. 48. The device of claim 47, wherein said first, second and third rings are all angled with respect to the normal by substantially the same degree of angulation. 49. A device for use in making an angled anastomosis between tubular fluid conduits in the body of a patient, said device comprising: a unitary structure having a main body disposed annularly about a longitudinal axis and having first and second end portions each encircling an annulus that the longitudinal axis passes through and angled with respect to a normal to the longitudinal axis;said first end portion having: a first end angled with respect to the normal to the longitudinal axis, with a location on said first end that is furthest from said normal to the longitudinal axis at a location passing through said main body being opposite to a location on said first end that is nearest to said normal to the longitudinal axis at said location passing through said main body;a plurality of members extending radially outwardly from said first end portion; anda first ring member angled with respect to the normal, wherein said plurality of members extending radially outwardly from said first end portion extend from said first ring member;and said second end portion having: a plurality of spaced struts adapted to buckle in a radially outward direction upon axial compression of said device, wherein said struts are plastically deformed during buckling;a plurality of tines extending radially outwardly from said second end portion and adapted to mechanically engage an everted end of a first of the tubular fluid conduits; anda second ring member angled with respect to the normal, wherein said plurality of spaced struts extend from said second ring member toward said first ring member;a ring portion connected to said second ring member to form a second end of said device with said second ring portion, said second end being angled with respect to the normal by an angle less than the angulation of said first end portion with respect to the normal. 50. The device of claim 49, further comprising struts interconnecting said ring portion and said second ring member, said struts being adapted to collapse before the buckling of said plurality of spaced struts adapted to buckle in a radially outward direction. 51. The device of claim 49, wherein, upon collapse of said struts interconnecting said ring portion and said second ring member, said second end is oriented at substantially the same angle of orientation to the normal as said first end portion. 52. A device for use in making an angled anastomosis between tubular fluid conduits in the body of a patient, said device comprising: a unitary structure having a main body disposed annularly about a longitudinal axis and having first and second end portions each encircling an annulus that the longitudinal axis passes through and angled with respect to a normal to the longitudinal axis, said first end portion having a first end angled with respect to the normal to the longitudinal axis, with a location on said first end that is furthest from said normal to the longitudinal axis at a location passing through said main body being opposite to a location on said first end that is nearest to said normal to the longitudinal axis at said location passing through said main body;a plurality of members extending radially outwardly from said first end portion; andsaid second end portion having a plurality of spaced struts adapted to buckle in a radially outward direction upon axial compression of said device, wherein said struts are plastically deformed during buckling and wherein strut portions of said struts are formed of varying lengths, depending upon the relative position of each said strut in said device. 53. A device for use in making an angled anastomosis between first and second tubular fluid conduits in the body of a patient, said device comprising: a unitary structure having a main body disposed annularly about a longitudinal axis, having a proximal end portion with a proximal end, and a distal end portion with a distal end, and adapted for passing the first tubular conduit through an annulus defined by the main body;an exterior of said main body configured to be inserted through an opening in the second tubular conduit;at least one first member extending radially from said proximal end portion and angled toward a proximal direction of said device, relative to said longitudinal axis, and at least one second member extending radially from said proximal end portion and angled toward a distal direction of said device, relative to said longitudinal axis, said members extending from said proximal end portion configured to abut against an external wall of the second conduit upon angulation of said main body with respect to a wall of the second tubular conduit;said distal end portion being configured to buckle in response to axial compression of said device, wherein said distal end portion plastically deforms and is incapable of passing through said opening after buckling and exerts a compressive force between the first conduit and the wall of the second conduit upon buckling, while maintaining the angled configuration of the main body with respect to the second conduit; andlocking members fixed to said distal end portion and slidably received by said proximal end portion, wherein, upon buckling of said distal end portion, free ends of said locking members slide to extend proximally of said proximal end portion. 54. An anastomosis device comprising: a unitary structure having a main body having an outside diameter adapted to pass through and form a close fit with an opening formed in a wall of a conduit to be joined by anastomosis;said main body defining an annulus having an inside diameter, said annulus extending longitudinally through said body along a longitudinal axis thereof;said body having proximal and distal end portions angled at non-zero angles with respect to a normal to the longitudinal axis, said proximal and distal end portions having a proximal and distal end, respectively, said distal ends being uniformly angled with respect to said normal and said proximal ends being uniformly angled with respect to said normal;an extension portion extending from said proximal end portion, having a length sufficient to span the length of said main body, and configured to be incapable of passing through the opening;conduit retainers on said distal end portion adapted to retain a free end portion of a conduit having been passed through said annulus and everted over said proximal end portion; andlocking members fixed to said distal end portion and slidably received by said proximal end portion, wherein, upon buckling of said distal end portion, free ends of said locking members slide to extend proximally of said proximal end portion. 55. A device for use in making an angled anastomosis between tubular fluid conduits in the body of a patient, said device comprising: a unitary structure having a main body disposed annularly about a longitudinal axis and having first and second end portions each encircling an annulus that the longitudinal axis passes through and angled with respect to a normal to the longitudinal axis, said first end portion having a first end angled with respect to the normal to the longitudinal axis, with a location on said first end that is furthest from said normal to the longitudinal axis at a location passing through said main body being opposite to a location on said first end that is nearest to said normal to the longitudinal axis at said location passing through said main body;a plurality of members extending radially outwardly from said first end portion;a plurality of spaced locking tines integral with second end portion and slidably connecting with said first end portion; andsaid second end portion having a plurality of spaced struts adapted to buckle in a radially outward direction upon axial compression of said device, wherein said struts are plastically deformed during buckling. 56. The device of claim 55, wherein upon compression of said device, said locking tines slide with respect to said first end portion and extend beyond said first end portion, said locking tines being adapted to be bent over to lock the relative positions of said first and second end portions. 57. The device of claim 55, wherein said first end portion further comprises a plurality of eyelets axially aligned with said locking tines, through which said locking tines are slidably connected to said first end portion.
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