A method of increasing the hydrophilicity of a polymer surface, such as a contact lens surface, includes exposing the polymer substrate to a first plasma under conditions selected to generate free radicals on the surface of the polymer substrate. The method also includes reacting an organic compound
A method of increasing the hydrophilicity of a polymer surface, such as a contact lens surface, includes exposing the polymer substrate to a first plasma under conditions selected to generate free radicals on the surface of the polymer substrate. The method also includes reacting an organic compound with the free radicals on the surface of the polymer substrate to thereby form an organic coating. The method further includes exposing the organic coating to a second plasma under conditions selected to oxidize the organic coating to thereby form a hydrophilic layer at the substrate surface. The hydrophilic layer can have a contact angle with respect to water that is less than about 50°.
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1. A method of increasing the hydrophilicity of a polymer surface, comprising: exposing a polymer substrate to a first plasma under conditions selected to generate free radicals on a surface of the polymer substrate;reacting an organic compound with the free radicals on the surface of the polymer su
1. A method of increasing the hydrophilicity of a polymer surface, comprising: exposing a polymer substrate to a first plasma under conditions selected to generate free radicals on a surface of the polymer substrate;reacting an organic compound with the free radicals on the surface of the polymer substrate to thereby form an organic coating, wherein the organic compound is methanol; andexposing the organic coating to a second plasma under conditions selected to oxidize the organic coating to thereby form a hydrophilic layer at the substrate surface. 2. The method of claim 1, wherein the polymer substrate is a contact lens or portion thereof. 3. The method of claim 1, wherein the first plasma is selected from an oxygen plasma, nitrogen plasma, ozone plasma, and hydrogen peroxide plasma. 4. The method of claim 1, wherein the polymer substrate is exposed to the first plasma for an exposure time in the range of from about 10 seconds to about 2 minutes. 5. The method of claim 1, wherein reacting an organic compound with the free radicals on the surface of the polymer substrate comprises contacting the organic compound with the polymer substrate in the presence of an alternating electric field. 6. The method of claim 1, wherein the second plasma is an oxygen plasma, an ozone plasma, or a hydrogen peroxide plasma. 7. The method of claim 6, wherein the organic coating is exposed to the second plasma for an exposure time in the range of from about 7 seconds to about 28 seconds. 8. The method of claim 1, wherein the contact angle of water with respect to the hydrophilic layer is less than that of the surface of the polymer substrate prior to exposure to the first plasma. 9. The method of claim 8, wherein the contact angle of water with respect to the hydrophilic layer is reduced by at least half as compared to the polymer substrate prior to exposure to the first plasma. 10. The method of claim 1, further comprising cleaning the polymer substrate with a basic solution prior to exposure to the first plasma. 11. The method of claim 1, further comprising subjecting the polymer substrate to a vacuum under conditions selected to substantially remove water at the surface of the substrate prior to exposure to the first plasma. 12. The method of claim 1, wherein the method is performed with the polymer substrate mounted in a substantially horizontal orientation. 13. A method of reducing the hydrophobicity of a contact lens surface, comprising: providing a contact lens;exposing the contact lens to a first plasma under conditions selected to generate free radicals on a surface of the contact lens;contacting an organic compound with the free radicals on the surface of the contact lens under conditions selected to form a hydrophilic surface on the contact lens, the hydrophilic surface having a contact angle with respect to water that is less than about 50°. 14. The method of claim 13, wherein the organic compound is linear, branched or cyclic and wherein the organic compound is selected from the group consisting of a C1-C20 alcohol, a C1-C20 ether, a C1-C20 aldehyde, a C1-C20 ketone, a C1-C20 ester, a C1-C20 alkane, a C2-C20 alkenyl, a C6-C20 aryl, a C1-C20 organosilicon compound, C1-C20 organosilane compound, a C1-C20 organophosphorous compound, a C1-C20 organotitanium compound a C1-C20 organotin compound, a C1-C20 organogermanium compound, and a C1-C20 organoboron compound. 15. The method of claim 13, wherein the organic compound has the formula R—O—R′, where R and R′ are each independently selected from H, linear C1-C10 alkyl, branched C1-C10 alkyl, cyclic C3-C10 alkyl, linear C2-C10 alkenyl, branched C2-C10 alkenyl, and cyclic C3-C10 alkenyl, with the proviso that R and R′ may not both be selected to be H; or R and R′ may be joined together to form a C4-C5 cyclic ether. 16. The method of claim 13, wherein the organic compound is a ketone of the formula R—(C═O)—R′ or an ester of the formula R—(C═O)—OR′, where R and R′ are independently selected from H, linear C1-C10 alkyl, branched C1-C10 alkyl, cyclic C3-C10 alkyl, linear C2-C10 alkenyl, branched C2-C10 alkenyl, and cyclic C3-C10 alkenyl; or R and R′ may be joined together to form a cyclic C3-C6 ketone or C3-C6 lactone. 17. The method of claim 13, wherein the organic compound is selected from the group consisting of a C1-C20 organosilicon compound, a C1-C20 organosilane compound, a C1-C20 organophosphorous compound, a C1-C20 organotitanium compound, a C1-C20 organotin compound, a C1-C20 organogermanium compound, and a C1-C20 organoboron compound. 18. The method of claim 13, wherein the organic compound is methanol. 19. The method of claim 13, wherein the first plasma is an oxygen plasma, a nitrogen plasma, an ozone plasma, or a hydrogen peroxide plasma. 20. The method of claim 13, wherein the contact lens is exposed to the first plasma for an exposure time in the range of from about 10 seconds to about 2 minutes. 21. The method of claim 13, wherein the conditions selected to form a hydrophilic surface on the contact lens comprise reacting the organic compound with the free radicals on the surface of the contact lens to form an organic coating. 22. The method of claim 13, wherein contacting the organic compound with the free radicals on the surface of the contact lens comprises contacting the organic compound with the contact lens in the presence of an alternating electric field. 23. The method of claim 21, further comprising oxidizing the organic coating by exposure to a second plasma. 24. The method of claim 23, wherein the plasma is one of an oxygen plasma, an ozone plasma, and a hydrogen peroxide plasma. 25. The method of claim 23, wherein the contact lens is exposed to the second plasma for between about 7 sec to about 28 sec. 26. The method of claim 23, wherein the power applied to the second plasma is in the range of about 200 Watts to about 450 Watts. 27. The method of claim 13, wherein the method is performed with the contact lens mounted in a substantially horizontal orientation.
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이 특허에 인용된 특허 (61)
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