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A human shoe sole or insole, sockliner or orthotic for insertion into a human shoe having a foot supporting upper surface including a first region for supporting the first, second, third, fourth and optionally fifth metatarsal heads of the foot, and a second region surrounding the first region for s

A human shoe sole or insole, sockliner or orthotic for insertion into a human shoe having a foot supporting upper surface including a first region for supporting the first, second, third, fourth and optionally fifth metatarsal heads of the foot, and a second region surrounding the first region for supporting the remainder of the foot, at least in part. The first region provides less resistance to downward motion than the second region, and includes a hollow or depressed area relative to the remainder of the first region having a medial border portion and a lateral border portion, wherein the depression has its lowest point skewed to the medial side of center, whereby to promote eversion of the first metatarsal head as the wearer moves from midstance through propulsive phase.

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1. A human shoe sole having a foot supporting upper surface including a first region for supporting the first, second, third, fourth and optionally fifth metatarsal heads of the foot, and a second region surrounding the first region for supporting the remainder of the foot, at least in part, wherein

1. A human shoe sole having a foot supporting upper surface including a first region for supporting the first, second, third, fourth and optionally fifth metatarsal heads of the foot, and a second region surrounding the first region for supporting the remainder of the foot, at least in part, wherein the first region provides less resistance to downward motion than the second region, wherein the first region includes a hollow or depressed area relative to the remainder of the first region having a medial border portion and a lateral border portion, wherein the depression has its lowest point skewed to the medial side of center, whereby to promote eversion of the first metatarsal head as the wearer moves from midstance through propulsive phase. 2. The human shoe sole of claim 1, wherein the first region has a lower durometer than the second region. 3. The shoe sole according to claim 2, wherein the first region has a Short A hardness of 30-35. 4. The shoe sole according to claim 1, wherein the first region is formed of a plug of material surrounded by the second region. 5. The shoe sole according to claim 1, wherein the depressed area comprises an opening formed in the sole and extending from the upper surface thereof. 6. The shoe sole according to claim 1, wherein the depression comprises a hollow formed below the upper surface of the sole. 7. The shoe sole according to claim 1, wherein the depression has a normal depth of 2-3 mm measured from a top edge of a side wall to the lowest point of the depression. 8. The shoe sole according to claim 1, wherein the depression is substantially circular in plan. 9. The shoe sole according to claim 1, wherein the depression is oval or egg-shaped in plan. 10. The shoe sole according to claim 1, wherein the depression is elongated and slightly wider at its toeward end. 11. An insole for insertion into a human shoe having a foot supporting upper surface including a first region for supporting the first, second, third, fourth and optionally fifth metatarsal heads of the foot, and a second region surrounding the first region for supporting the remainder of the foot, at least in part, wherein the first region provides less resistance to downward motion than the second region, wherein the first region includes a hollow or depressed area relative to the remainder of the first region having a medial border portion and a lateral border portion, wherein the depression has its lowest point skewed to the medial side of center, whereby to promote eversion of the first metatarsal head as the wearer moves from midstance through propulsive phase. 12. The insole of claim 11, wherein the first region has a lower durometer than the second region. 13. The insole according to claim 12, wherein the first region has a Shore A hardness of 30-35. 14. The insole according to claim 11, wherein the first region is formed of a plug of material surrounded by the second region. 15. The insole according to claim 11, wherein the depressed area comprises an opening formed in the sole and extending from the upper surface thereof. 16. The insole according to claim 11, wherein the depression comprises a hollow formed below the upper surface of the insole. 17. The insole according to claim 11, wherein depression has a normal depth of 2-3 mm measured from a top edge of a side wall to the lowest point of the depression. 18. The insole according to claim 11, wherein the depression is substantially circular in plan. 19. The insole according to claim 11, wherein the depression is oval or egg-shaped in plan. 20. The insole according to claim 19, wherein the depression is elongated and slightly wider at its toeward end. 21. A sockliner for insertion into a human shoe having a foot supporting upper surface including a first region for supporting the first, second, third, fourth and optionally fifth metatarsal heads of the foot, and a second region surrounding the first region for supporting the remainder of the foot, at least in part, wherein the first region provides less resistance to downward motion than the second region, wherein the first region includes a hollow or depressed area relative to the remainder of the first region having a medial border portion and a lateral border portion, wherein the depression has its lowest point skewed to the medial side of center, whereby to promote eversion of the first metatarsal head as the wearer moves from midstance through propulsive phase. 22. The sockliner of claim 21, wherein the first region has a lower durometer than the second region. 23. The sockliner according to claim 22, wherein the first region has a Shore A hardness of 30-35. 24. The sockliner according to claim 21, wherein the first region is formed of a plug of material surrounded by the second region. 25. The sockliner according to claim 21, wherein the depressed area comprises an opening formed in the sole and extending from the upper surface thereof. 26. The sockliner according to claim 21, wherein the depression comprises a hollow formed below the upper surface of the sockliner. 27. The sockliner according to claim 21, wherein the normal depth of 2-3 mm measured from a top edge of a side wall to the lowest point of the depression. 28. The sockliner according to claim 21, wherein the depression is substantially circular in plan. 29. The sockliner according to claim 21 wherein the depression is oval or egg-shaped in plan. 30. The sockliner according to claim 29, wherein the depression is elongated and slightly wider at its toeward end. 31. An orthotic for insertion into a human shoe sole having a foot supporting upper surface including a first region for supporting the first, second, third, fourth and optionally fifth metatarsal heads of the foot, and a second region surrounding the first region for supporting the remainder of the foot, at least in part, wherein the first region provides less resistance to downward motion than the second region, wherein the first region includes a hollow or depressed area relative to the remainder of the first region having a medial border portion and a lateral border portion, wherein the depression has its lowest point skewed to the medial side of center, whereby to promote eversion of the first metatarsal head as the wearer moves from midstance to propulsive phase. 32. The orthotic of claim 31, wherein the first region has a lower durometer than the second region. 33. The orthotic according to claim 32, wherein the first region has a Shore A hardness of 30-35. 34. The orthotic according to claim 31, wherein the first region is formed of a plug of material surrounded by the second portion. 35. The orthotic according to claim 31 wherein the depressed area comprises an opening formed in the sole and extending from the upper surface thereof. 36. The orthotic according to claim 31, wherein the depression comprises a hollow formed below the upper surface of the insole. 37. The orthotic according to claim 31, wherein the depression has normal depth of 2-3 mm measured from a top edge of a side wall to the lowest point of the depression. 38. The orthotic according to claim 31 wherein the depression is substantially circular in plan. 39. The orthotic according to claim 31, wherein the depression is oval or egg-shaped in plan. 40. The orthotic according to claim 39, wherein the depression is elongated and slightly wider at its toeward end. 41. The orthotic of claim 31, wherein the orthotic is a custom orthotic. 42. The orthotic of claim 31, wherein the orthotic is a prefabricated orthotic.