IPC분류정보
국가/구분 |
United States(US) Patent
등록
|
국제특허분류(IPC7판) |
|
출원번호 |
US-0499142
(2009-07-08)
|
등록번호 |
US-8173722
(2012-05-08)
|
우선권정보 |
DE-10 2008 033 378 (2008-07-10); DE-10 2009 007 253 (2009-01-27) |
발명자
/ 주소 |
- Baiker, Anja
- Haertel, Claudia
- Odermatt, Erich
- Siedle, Gabriel
- Sterk, Thomas
- Wegmann, Juergen
|
출원인 / 주소 |
|
대리인 / 주소 |
|
인용정보 |
피인용 횟수 :
7 인용 특허 :
6 |
초록
▼
An adhesive composition for use in surgical therapy includes at least the following components a) and b): a) a liquid mixture including cyanoactrylate monomers and at least one plasticizer, where the proportion of the at least one plasticizer in component a) is greater than 10% by weight based on th
An adhesive composition for use in surgical therapy includes at least the following components a) and b): a) a liquid mixture including cyanoactrylate monomers and at least one plasticizer, where the proportion of the at least one plasticizer in component a) is greater than 10% by weight based on the total weight of component a), and b) an aqueous liquid including at least one compound from the group of borate salt, basic amino acid, gelatin and gelatin derivative.
대표청구항
▼
1. An adhesive composition comprising components a) and b): a) a liquid mixture including cyanoacrylate monomers and at least one plasticizer, where the proportion of the at least one plasticizer in component a) is greater than 10% by weight based on the total weight of component a), andb) an aqueou
1. An adhesive composition comprising components a) and b): a) a liquid mixture including cyanoacrylate monomers and at least one plasticizer, where the proportion of the at least one plasticizer in component a) is greater than 10% by weight based on the total weight of component a), andb) an aqueous liquid including basic amino acid. 2. The adhesive composition as claimed in claim 1, wherein components a) and b) are spatially separated from one another. 3. The adhesive composition as claimed in claim 1, wherein components a) and b) are each present in one compartment of an application device. 4. The adhesive composition as claimed in claim 1, which is set by mixing components a) and b) to give a gel, a paste or a flexible membrane. 5. The adhesive composition as claimed in claim 1, wherein the at least one plasticizer is a plasticizer soluble in cyanoacrylate monomers. 6. The adhesive composition as claimed in claim 1, wherein component a) is in the form of a solution. 7. The adhesive composition as claimed in claim 1, wherein the at least one plasticizer is a plasticizer inert toward cyanoacrylate monomers. 8. The adhesive composition as claimed in claim 1, wherein the proportion of the at least one plasticizer in component a) is greater than about 20% by weight, based on the total weight of component a). 9. The adhesive composition as claimed in claim 1, having, after mixing components a) and b), a pot life or gel time t of 0≦t≦300 s. 10. The adhesive composition as claimed in claim 1, wherein components a) and b) are present in a mixing ratio of between 1:10 and 10:1 by volume. 11. The adhesive composition as claimed in claim 1, wherein the cyanoacrylate monomers are selected from the group consisting of alkyl cyanoacrylate monomers, alkoxyalkyl cyanoacrylate monomers, alkyl ester cyanoacrylate monomers and mixtures thereof. 12. The adhesive composition as claimed in claim 1, wherein the cyanoacrylate monomers are selected from the group consisting of n-butyl cyanoacrylate monomers, i-butyl cyanoacrylate monomers, n-hexyl cyanoacrylate monomers, n-octyl cyanoacrylate monomers, ethoxyethyl cyanoacrylate monomers, methoxypropyl cyanoacrylate monomers, methoxybutyl cyanoacrylate monomers, butyllactoyl cyanoacrylate monomers and mixtures thereof. 13. The adhesive composition as claimed in claim 1, wherein the at least one plasticizer is selected from the group consisting of citric esters, glycerol esters, sebacic esters, fatty acid esters, cellulose esters, polyethylene glycol ethers and mixtures thereof. 14. The adhesive composition as claimed in claim 1, wherein the proportion of the at least one compound in component b) is between about 0.01 and about 25% by weight, based on the total weight of component b). 15. The adhesive composition as claimed in claim 1, wherein the basic amino acid is selected from the group consisting of histidine, lysine, arginine, derivatives thereof and mixtures thereof. 16. The adhesive composition as claimed in claim 1, wherein component b) is in the form of an aqueous solution. 17. The adhesive composition as claimed in claim 1, wherein component b) further comprises at least one plasticizer. 18. The adhesive composition as claimed in claim 1, which is a medical adhesive composition that bonds human and/or animal hard and/or soft tissues. 19. An adhesive union prepared or preparable from an adhesive composition as claimed in claim 1. 20. A kit comprising two containers, wherein one container comprises component a) and the other container comprises component b) of the adhesive composition as claimed in claim 1. 21. The kit as claimed in claim 20, wherein the two containers are in each case a chamber of a two-chamber syringe. 22. The kit as claimed in claim 20, comprising a unit for mixing components a) and b), comprising a static or dynamic mixer or a spray head, which can be fitted onto a two-chamber syringe. 23. An application device comprising an adhesive composition as claimed in claim 1. 24. A method of sealing liquid and/or air leaks or closing cavities and/or vessels in a human and/or animal body comprising applying an adhesive composition comprising a) liquid mixture comprising cyanoacrylate monomers and at least one plasticizer, with a plasticizer content in component a) of greater than 10% by weight based on the total weight of component a), and b) an aqueous liquid comprising a basic amino acid. 25. An antimicrobial closure of superficial and/or internal wounds comprising an adhesive composition comprising a) liquid mixture comprising cyanoacrylate monomers and at least one plasticizer, with a plasticizer content in component a) of greater than 10% by weight based on the total weight of component a), and b) an aqueous liquid comprising a basic amino acid.
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