Nutritional supplement for use under physiologically stressful conditions
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A61K-033/26
A61K-033/34
A61K-033/32
A61K-033/06
A61K-033/04
A61K-031/28
A61K-031/04
A61K-031/295
A61K-031/30
A01N-059/16
A01N-059/20
A01N-059/06
A01N-059/02
A01N-055/02
A01N-043/08
출원번호
US-0698174
(2010-02-02)
등록번호
US-8202546
(2012-06-19)
발명자
/ 주소
Squashic, Steven A.
Hudy, Kevin M.
Purdy, David C.
출원인 / 주소
Vertical Pharmaceuticals, Inc.
대리인 / 주소
Maldjian Law Group LLC
인용정보
피인용 횟수 :
0인용 특허 :
194
초록▼
In one embodiment of the present invention, a pharmaceutically-acceptable single-dosage formulation consists essentially of about 300 mg of vitamin C; about 1200 IUs of vitamin D3; about 125 IUs of vitamin E; about 25 mg of vitamin B1; about 3.4 mg of vitamin B2; about 35 mg of niacin; about 35 mg o
In one embodiment of the present invention, a pharmaceutically-acceptable single-dosage formulation consists essentially of about 300 mg of vitamin C; about 1200 IUs of vitamin D3; about 125 IUs of vitamin E; about 25 mg of vitamin B1; about 3.4 mg of vitamin B2; about 35 mg of niacin; about 35 mg of vitamin B6; about 1.25 mg of folate; about 70 mcg of vitamin B12; about 5 mg of pantothenic acid; about 300 mcg of biotin; about 50 mg of calcium; about 35 mg of magnesium; about 35 mg of zinc; about 1 mg of copper; about 125 mcg of selenium; about 150 mcg of chromium; about 25 mg of alpha lipoic acid; about 35 mg of co-enzyme Q-10; about 2 mg of lutein; about 500 mcg of lycopene; about 5 mg of pepper extract; and at least one or more excipients.
대표청구항▼
1. A pharmaceutically-acceptable single-dosage formulation, consisting essentially of: between about 150 mg to about 450 mg of vitamin C;between about 600 IUs to about 1800 IUs of vitamin D3;between about 75 IUs to about 150 IUs of vitamin E;between about 15 mg to about 35 mg of vitamin B1;between a
1. A pharmaceutically-acceptable single-dosage formulation, consisting essentially of: between about 150 mg to about 450 mg of vitamin C;between about 600 IUs to about 1800 IUs of vitamin D3;between about 75 IUs to about 150 IUs of vitamin E;between about 15 mg to about 35 mg of vitamin B1;between about 1.7 mg to about 5.1 mg of vitamin B2;between about 20 mg to about 50 mg of niacin;between about 20 mg to about 50 mg of vitamin B6;between about 0.5 mg to about 2.5 mg of folate;between about 35 mcg to about 105 mcg of vitamin B12;between about 2.5 mg to about 7.5 mg of pantothenic acid;between about 150 mcg to about 450 mcg of biotin;between about 50 mg to about 100 mg of calcium;between about 15 mg to about 55 mg of magnesium;between about 15 mg to about 55 mg of zinc;between about 0.5 to about 1.5 mg of copper;between about 75 mcg to about 175 mcg of selenium;between about 75 mcg to about 225 mcg of chromium;between about 10 mg to about 40 mg of alpha lipoic acid;between about 20 mg to about 50 mg of co-enzyme Q-10;between about 1 mg to about 3 mg of lutein;between about 250 mcg to about 750 mcg of lycopene;between about 2.5 mg to about 7.5 mg of pepper extract; andat least one or more excipients. 2. The pharmaceutically-acceptable single-dosage formulation of claim 1, wherein the formulation consists essentially of: about 300 mg of vitamin C;about 1200 IUs of vitamin D3;about 125 IUs of vitamin E;about 25 mg of vitamin B1;about 3.4 mg of vitamin B2;about 35 mg of niacin;about 35 mg of vitamin B6;about 1.25 mg of folate;about 70 mcg of vitamin B12;about 5 mg of pantothenic acid;about 300 mcg of biotin;about 75 mg of calcium;about 35 mg of magnesium;about 35 mg of zinc;about 1 mg of copper;about 125 mcg of selenium;about 150 mcg of chromium;about 25 mg of alpha lipoic acid;about 35 mg of co-enzyme Q-10;about 2 mg of lutein;about 500 mcg of lycopene;about 5 mg of pepper extract; andat least one or more excipients. 3. The formulation of claim 1, wherein the single-dosage formulation is administered in a form selected from the group consisting of a pill, a tablet, a caplet, a capsule, a chewable tablet, a quick dissolve tablet, an effervescent tablet, a hard gelatin capsule, and a soft gelatin capsule. 4. The formulation of claim 3, wherein the single-dosage formulation is administered in a form with an enteric coating. 5. The formulation of claim 1, wherein the single-dosage formulation is administered in the form of a liquid suspension. 6. The formulation of claim 1, wherein the single-dosage formulation is administered in the form of a food product. 7. The formulation of claim 1, wherein the excipients consist essentially of at least one of dicalcium phosphate, microcrystalline cellulose, stearic acid, croscarmellose sodium, magnesium trisillicate, magnesium stearate or hydroxypropyl methylcellulose. 8. The formulation of claim 1, wherein the at least one or more excipients consist of: between about 100 mg to about 300 mg of dicalcium phosphate;between about 25 mg to about 75 mg of microcrystalline cellulose;between about 10 mg to about 30 mg of stearic acid;between about 10 mg to about 30 mg of croscarmellose sodium;between about 5 mg to about 15 mg of magnesium trisillicate;between about 5 mg to about 15 mg of magnesium stearate; andbetween about 5 mg to about 15 mg of hydroxypropyl methylcellulose. 9. The formulation of claim 8, wherein the at least one or more excipients consist of: about 200 mg of dicalcium phosphate;about 50 mg of microcrystalline cellulose;about 20 mg of stearic acid;about 20 mg of croscarmellose sodium;about 10 mg of magnesium trisillicate;about 10 mg of magnesium stearate; andabout 10 mg of hydroxypropyl methylcellulose. 10. A pharmaceutically-acceptable single-dosage formulation, consisting of: between about 150 mg to about 450 mg of ascorbic acid;between about 600 IUs to about 1800 IUs of cholecalciferol;between about 75 IUs to about 150 IUs of d-alpha tocopherol succinate;between about 15 mg to about 35 mg of thiamine mononitrate;between about 1.7 mg to about 5.1 mg of riboflavin;between about 20 mg to about 50 mg of niacinamide;between about 20 mg to about 50 mg of pyridoxine hcl;between about 0.5 mg to about 2.5 mg of folic acid;between about 35 mcg to about 105 mcg of cyanocobalamin;between about 2.5 mg to about 7.5 mg of d-calcium pantothenate;between about 150 mcg to about 450 mcg of d-biotin;between about 50 mg to about 100 mg of dicalcium malate;between about 15 mg to about 55 mg of dimagnesium malate;between about 15 mg to about 55 mg of zinc bisglycinate chelate;between about 0.5 to about 1.5 mg of copper amino acid chelate;between about 75 mcg to about 175 mcg of selenium amino acid chelate;between about 75 mcg to about 225 mcg of chromium amino acid chelate;between about 10 mg to about 40 mg of alpha lipoic acid;between about 20 mg to about 50 mg of co-enzyme Q-10;between about 1 mg to about 3 mg of lutein;between about 250 mcg to about 750 mcg of lycopene;between about 2.5 mg to about 7.5 mg of pepper extract; andat least one or more excipients. 11. The pharmaceutically-acceptable single-dosage formulation of claim 10, wherein the formulation consists of: about 300 mg of ascorbic acidabout 1200 IUs of cholecalciferol;about 125 IUs of d-alpha tocopherol succinate;about 35 mg of thiamine mononitrate;about 5.1 mg of riboflavin;about 50 mg of niacinamide;about 50 mg of pyridoxine hcl;about 2.5 mg of folic acid;about 105 mcg of cyanocobalamin;about 7.5 mg of d-calcium pantothenate;about 450 mcg of d-biotin;about 75 mg of dicalcium malate;about 55 mg of dimagnesium malate;about 55 mg of zinc bisglycinate chelate;about 1.5 mg of copper amino acid chelate;about 175 mcg of selenium amino acid chelate;about 225 mcg of chromium amino acid chelate;about 40 mg of alpha lipoic acid;about 50 mg of co-enzyme Q-10;about 3 mg of lutein;about 750 mcg of lycopene;about 7.5 mg of pepper extract; andat least one or more excipients. 12. The formulation of claim 10, wherein the single-dosage formulation is administered in a form selected from the group consisting of a pill, a tablet, a caplet, a capsule, a chewable tablet, a quick dissolve tablet, an effervescent tablet, a hard gelatin capsule, and a soft gelatin capsule. 13. The formulation of claim 12, wherein the single-dosage formulation is administered in a form with an enteric coating. 14. The formulation of claim 10, wherein the single-dosage formulation is administered in the form of a liquid suspension. 15. The formulation of claim 10, wherein the single-dosage formulation is administered in the form of a food product. 16. The formulation of claim 10, wherein the excipients consist of at least one of dicalcium phosphate, microcrystalline cellulose, stearic acid, croscarmellose sodium, magnesium trisillicate, magnesium stearate or hydroxypropyl methylcellulose. 17. The formulation of claim 10, wherein the at least one or more excipients consist of: between about 100 mg to about 300 mg of dicalcium phosphate;between about 25 mg to about 75 mg of microcrystalline cellulose;between about 10 mg to about 30 mg of stearic acid;between about 10 mg to about 30 mg of croscarmellose sodium;between about 5 mg to about 15 mg of magnesium trisillicate;between about 5 mg to about 15 mg of magnesium stearate; andbetween about 5 mg to about 15 mg of hydroxypropyl methylcellulose. 18. The formulation of claim 17, wherein the at least one or more excipients consist of: about 200 mg of dicalcium phosphate;about 50 mg of microcrystalline cellulose;about 20 mg of stearic acid;about 20 mg of croscarmellose sodium;about 10 mg of magnesium trisillicate;about 10 mg of magnesium stearate; andabout 10 mg of hydroxypropyl methylcellulose. 19. A pharmaceutically-acceptable single-dosage formulation, consisting of: between about 150 mg to about 450 mg of ascorbic acid;between about 600 IUs to about 1800 IUs of cholecalciferol;between about 75 IUs to about 150 IUs of d-alpha tocopherol succinate;between about 15 mg to about 35 mg of thiamine mononitrate;between about 1.7 mg to about 5.1 mg of riboflavin;between about 20 mg to about 50 mg of niacinamide;between about 20 mg to about 50 mg of pyridoxine hcl;between about 0.5 mg to about 2.5 mg of folic acid;between about 35 mcg to about 105 mcg of cyanocobalamin;between about 2.5 mg to about 7.5 mg of d-calcium pantothenate;between about 150 mcg to about 450 mcg of d-biotin;between about 50 mg to about 100 mg of dicalcium malate;between about 15 mg to about 55 mg of dimagnesium malate;between about 15 mg to about 55 mg of zinc bisglycinate chelate;between about 0.5 to about 1.5 mg of copper amino acid chelate;between about 75 mcg to about 175 mcg of selenium amino acid chelate;between about 75 mcg to about 225 mcg of chromium amino acid chelate;between about 10 mg to about 40 mg of alpha lipoic acid;between about 20 mg to about 50 mg of co-enzyme Q-10;between about 1 mg to about 3 mg of lutein;between about 250 mcg to about 750 mcg of lycopene;between about 2.5 mg to about 7.5 mg of pepper extract;between about 100 mg to about 300 mg of dicalcium phosphate;between about 25 mg to about 75 mg of microcrystalline cellulose;between about 10 mg to about 30 mg of stearic acid;between about 10 mg to about 30 mg of croscarmellose sodium;between about 5 mg to about 15 mg of magnesium trisillicate;between about 5 mg to about 15 mg of magnesium stearate; andbetween about 5 mg to about 15 mg of hydroxypropyl methylcellulose;wherein the single-dosage formulation is administered in a form selected from a group consisting of a pill, a tablet, a caplet, a capsule, a chewable tablet, a quick dissolve tablet, an effervescent tablet, a hard gelatin capsule, a soft gelatin capsule, a liquid suspension or a food product. 20. The pharmaceutically-acceptable single-dosage formulation of claim 19, wherein the formulation consists of: about 300 mg of ascorbic acidabout 1200 IUs of cholecalciferol;about 125 IUs of d-alpha tocopherol succinate;about 35 mg of thiamine mononitrate;about 5.1 mg of riboflavin;about 50 mg of niacinamide;about 50 mg of pyridoxine hcl;about 2.5 mg of folic acid;about 105 mcg of cyanocobalamin;about 7.5 mg of d-calcium pantothenate;about 450 mcg of d-biotin;about 75 mg of dicalcium malate;about 55 mg of dimagnesium malate;about 55 mg of zinc bisglycinate chelate;about 1.5 mg of copper amino acid chelate;about 175 mcg of selenium amino acid chelate;about 225 mcg of chromium amino acid chelate;about 40 mg of alpha lipoic acid;about 50 mg of co-enzyme Q-10;about 3 mg of lutein;about 750 mcg of lycopene;about 7.5 mg of pepper extract;about 200 mg of dicalcium phosphate;about 50 mg of microcrystalline cellulose;about 20 mg of stearic acid;about 20 mg of croscarmellose sodium;about 10 mg of magnesium trisillicate;about 10 mg of magnesium stearate; andabout 10 mg of hydroxypropyl methylcellulose.
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