A system for mixing or reconstituting a drug contained in a first container with a diluent or fluid contained in a second container. The second container has a port docking assembly for engaging the first container. The first container is rotatable and axially slidable within the port docking assemb
A system for mixing or reconstituting a drug contained in a first container with a diluent or fluid contained in a second container. The second container has a port docking assembly for engaging the first container. The first container is rotatable and axially slidable within the port docking assembly. The port docking assembly has an actuator to urge a stopper fluidly sealing the first container into the interior of the first container. The port docking assembly further includes a movable plug constructed to fluidly seal the second container in a first, docked position and to provide access to the interior of the second container in a second, activated position, whereby fluid communication between the first and second containers is provided when the first and second containers are in the second, activated position.
대표청구항▼
1. A port assembly for a container storing a fluid to be mixed with a medicament in a vial, said port assembly comprising: a port housing defining a first opening at a proximal end thereof, said first opening providing access to a cavity defined within said port housing, said port housing defining a
1. A port assembly for a container storing a fluid to be mixed with a medicament in a vial, said port assembly comprising: a port housing defining a first opening at a proximal end thereof, said first opening providing access to a cavity defined within said port housing, said port housing defining a second opening spaced from said first opening, said second opening also providing access to said cavity defined within said port housing, and an axially movable plug sealing said second opening;a retainer positioned in said cavity to retain a vial in a docked position; andan actuator axially fixed within said cavity of said port housing between said first and said second openings, said actuator comprising a plurality of sidewall members extending axially toward said first opening of said port housing, one or more openings being defined between said sidewall members, and a central cavity defined by said sidewall members, said actuator adapted to force a stopper associated with the vial into the vial during activation. 2. A port assembly in accordance with claim 1, wherein said plug has a plurality of legs extending axially toward said first opening, said legs adapted to engage the vial during activation to disengage said plug from said second opening of said port housing. 3. A port assembly in accordance with claim 1, wherein said port housing has a protrusion extending from an interior wall thereof to engage an activation collar associated with the vial and to prevent relative rotation between the activation collar associated with the vial and said port assembly. 4. A port assembly in accordance with claim 1, wherein said retainer further comprises a flange defining an opening, said port assembly further comprising a peelable cover sealing said opening defined by said retainer flange. 5. A port assembly in accordance with claim 4, wherein said port assembly further comprises an overcap removably sealing said opening defined by said retainer flange, said overcap positioned external to said peelable cover. 6. A port assembly in accordance with claim 1, wherein said port assembly is bonded to a flexible container constructed of a polymeric material, wherein said port assembly provides fluid communication between an exterior and an interior of said flexible container. 7. A port assembly in accordance with claim 6, wherein said flexible container is constructed of a non-PVC material. 8. The port assembly of claim 1, wherein said axially moveable plug is configured to move axially relative to said actuator during activation, thereby opening said second opening of said port housing. 9. The port assembly of claim 1, wherein said retainer comprises a plurality of retainer tabs. 10. The port assembly of claim 9, wherein at least one of said retainer tabs is a first length and at least one other said retainer tabs is a second length. 11. A port assembly for a container storing a fluid to be mixed with a medicament in a vial, said port assembly comprising: a port housing comprising a first opening that provides access to a cavity defined within said port housing, a retainer positioned in said cavity to retain the vial, and a second opening axially spaced from said first opening that also provides access to said cavity defined within said port housing, andan actuator axially fixed within said cavity of said port housing between said first and said second openings, said actuator comprising a plurality of sidewall members extending axially towards said first opening of said port housing, wherein said actuator is adapted to force a stopper associated with the vial into the vial during activation. 12. The port assembly of claim 11, further comprising an axially moveable plug sealing said second opening. 13. The port assembly of claim 12, wherein said axially moveable plug is configured to move axially relative to said actuator during activation, thereby opening said second opening of said port housing. 14. The port assembly of claim 12, wherein said plug has a plurality of legs extending axially toward said first opening, said legs adapted to engage the vial during activation to disengage said plug from said second opening of said port housing. 15. The port assembly of claim 11, wherein said retainer comprises a plurality of retainer tabs. 16. The port assembly of claim 15, wherein at least one of said retainer tabs is a first length and at least one other said retainer tabs is a second length.
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