최소 단어 이상 선택하여야 합니다.
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다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
NTIS 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
DataON 바로가기다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
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Kafe 바로가기국가/구분 | United States(US) Patent 등록 |
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국제특허분류(IPC7판) |
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출원번호 | US-0136537 (2008-06-10) |
등록번호 | US-8236046 (2012-08-07) |
발명자 / 주소 |
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출원인 / 주소 |
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대리인 / 주소 |
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인용정보 | 피인용 횟수 : 13 인용 특허 : 572 |
An endoprosthesis can include a body including an underlying portion and a surface portion overlying the underlying portion. The underlying portion can include a bioerodible metal in the form of a matrix and corrosion enhancing deposits within the matrix. The surface portion including the bioerodibl
An endoprosthesis can include a body including an underlying portion and a surface portion overlying the underlying portion. The underlying portion can include a bioerodible metal in the form of a matrix and corrosion enhancing deposits within the matrix. The surface portion including the bioerodible metal of the matrix. The surface portion having a first erosion rate when exposed to a physiological environment and the underlying portion having a second erosion rate when exposed to a physiological environment that is greater than the first erosion rate.
1. An endoprosthesis comprising a tubular member defined by a plurality of struts, at least one strut of the tubular member having a central longitudinal axis and including: (a) a central portion of the at least one strut that extends along the central longitudinal axis, the central portion lacking
1. An endoprosthesis comprising a tubular member defined by a plurality of struts, at least one strut of the tubular member having a central longitudinal axis and including: (a) a central portion of the at least one strut that extends along the central longitudinal axis, the central portion lacking corrosion enhancing deposits;(b) an underlying portion comprising a first bioerodible metal including a matrix and corrosion enhancing deposits within the matrix, the underlying portion extending radially outward from the central portion relative to the central longitudinal axis; the underlying portion having a thickness of at least 1 micrometer;(c) a surface portion having a thickness of between 0.1 micrometers and 3micrometers overlying and extending radially outward from the underlying portion relative to the central longitudinal axis, the surface portion comprising a second bioerodible metal having the composition of the matrix and being substantially free of corrosion enhancing deposits;the surface portion having a first erosion rate and the underlying portion having a second erosion rate that is greater than the first erosion rate when the surface portion and the underlying portion are exposed to physiological environments. 2. The endoprosthesis of claim 1, wherein the corrosion enhancing deposits of the underlying portion comprise nano-bubbles of noble gases. 3. The endoprosthesis of claim 2, wherein the nano-bubbles comprise helium, argon, neon, krypton, or a combination thereof. 4. The endoprosthesis of claim 2, wherein the nano-bubbles have an average diameter of between 1 nm and 600 nm. 5. The endoprosthesis of claim 1, wherein the corrosion enhancing deposits of the underlying portion comprise silver. 6. The endoprosthesis of claim 1, wherein the corrosion enhancing deposits of the underlying portion comprise manganese. 7. The endoprosthesis of claim 1, wherein the corrosion enhancing deposits in the underlying portion are more noble than the first bioerodible metal and form a galvanic couple with the first bioerodible metal when the corrosion enhancing deposits in the underlying portion are exposed to physiological environments and the corrosion enhancing deposits in the underlying portion act as an anode. 8. The endoprosthesis of claim 1, wherein the corrosion enhancing deposits in the underlying portion are less noble than the first bioerodible metal and form a galvanic couple with the first bioerodible metal when the corrosion enhancing deposits in the underlying portion are exposed to physiological environments and the corrosion enhancing deposits in the underlying portion act as an cathode. 9. The endoprosthesis of claim 1, wherein the surface portion consists essentially of the second bioerodible metal. 10. The endoprosthesis of claim 1, wherein the surface portion has a substantially smooth upper surface. 11. The endoprosthesis of claim 1, wherein the first and second bioerodible metals comprises iron or an alloy thereof. 12. The endoprosthesis of claim 1, wherein the endoprosthesis is a stent. 13. The endoprosthesis of claim 1, wherein the underlying portion has a thickness of between 2 and 3 micrometers.
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